Categories
Treatments

Molluscum Contagiosum: Symptoms, Causes, & More

Molluscum contagiosum is a common viral skin infection that presents as small, dome-shaped papules. It can affect children, adults, and individuals with specific risk factors. Though often harmless, its appearance may cause discomfort or cosmetic concern.

This article explains how molluscum contagiosum develops, its symptoms, transmission routes, and recognised treatment options for safe and effective management.

What Is Molluscum Contagiosum

Molluscum contagiosum is caused by the molluscum contagiosum virus, a member of the Poxviridae family. It produces smooth, raised, flesh-coloured lesions with a central dimple known as mollusca.

These lesions typically measure between 2 and 5 mm in diameter and are most common in children aged 1 to 10, though adults can also be affected. The infection usually clears within 6 to 12 months but may persist longer in individuals with weakened immune systems such as those living with HIV [1,2,3].

Molluscum contagiosum spreads easily in communal settings like swimming pools and playgrounds, and through close skin contact during activities or intimacy [2,4,6].

How Molluscum Contagiosum Spreads

Molluscum contagiosum spreads through direct skin contact with infected lesions or by touching contaminated objects such as towels, clothing, or toys [1]. Scratching can also spread the virus to other areas of the body, known as autoinoculation [3].

Among adults, sexual contact is a common route of transmission, leading to lesions in the genital or lower abdominal area [4]. Preventive care such as covering lesions, avoiding shared items, and maintaining hygiene significantly reduces transmission risk.

Recognising Molluscum Contagiosum Symptoms

Typical Lesion Appearance

The hallmark sign is a cluster of small, raised, flesh-coloured papules with a smooth surface and central indentation [1]. These are typically painless but may become itchy or inflamed if irritated.

Secondary Skin Changes

In some cases, eczema or mild redness develops around lesions, signalling the body’s immune response [3]. Avoiding scratching is important to prevent bacterial infection or scarring during healing.

Commonly Affected Areas

Age GroupTypical Locations
ChildrenFace, neck, arms, and hands
AdultsGenital area, lower abdomen, inner thighs

Table 1: Common lesion sites and age-related patterns

Diagnosing Molluscum Contagiosum

Healthcare professionals diagnose molluscum contagiosum primarily through clinical examination [1]. The condition’s distinct appearance usually eliminates the need for further tests.

If uncertainty arises, a biopsy may confirm the diagnosis by identifying Henderson-Patterson bodies, which are microscopic inclusions specific to this virus [3]. Accurate diagnosis ensures appropriate care and reassurance.

Treatment For Molluscum Contagiosum

Although the condition often clears naturally, treatment may be recommended to shorten duration, ease symptoms, or prevent spread. A healthcare professional can advise on suitable options.

Treatment MethodDescriptionBenefitsConsiderations
Topical TreatmentsApplication of solutions such as potassium hydroxide or salicylic acid [3]Non-invasive and can accelerate clearanceMay cause redness or irritation
Physical RemovalCryotherapy or curettage to remove lesions [1]Immediate lesion reductionTemporary discomfort or mild scarring possible
Oral MedicationsImmunomodulatory therapy in select severe cases [5,6]May reduce lesion count in immunocompromised patientsUsed only under supervision

Table 2: Evidence-based treatment options for molluscum contagiosum

Preventing Molluscum Contagiosum

Good hygiene and protective habits help prevent transmission and reinfection.

Preventive MeasureDescription
Avoid Sharing Personal ItemsDo not share towels, clothing, or personal care objects
Cover LesionsUse waterproof dressings or clothing, especially during swimming [2]
Practice Safe ContactMaintain hygiene during intimacy or sports [4]
Wash Hands RegularlyReduces autoinoculation and spread to others [1]

Table 3: Preventive measures to limit transmission and reinfection

When To Seek Medical Advice

Molluscum contagiosum is self-limiting, but medical review is advised if:

  • Lesions appear in the genital area [4]
  • You have a weakened immune system [3]
  • Lesions become painful, inflamed, or infected [1]
  • The condition persists beyond 18 months [2]

Professional assessment ensures correct diagnosis and supports safe management.

Monderma’s Role In Skin Health

For individuals managing conditions such as acne, rosacea, or pigmentation, Monderma’s personalised skincare offers prescription-strength treatments designed by UK-registered prescribers. Each formulation is developed following an online clinical consultation to ensure suitability, safety, and results.

Molluscum contagiosum is viral and should be managed through medical care. Monderma’s treatments are designed to complement overall skin health but are not used to treat viral infections.

Conclusion

Molluscum contagiosum is a mild viral skin infection that often resolves naturally but may require treatment to prevent spread or discomfort. Understanding its symptoms, causes, and treatment options empowers individuals to manage their skin confidently and safely.

Practising good hygiene and seeking professional advice support faster recovery and protect others from infection. Explore Monderma’s free consultation to receive expert guidance on maintaining healthy, resilient skin.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. NHS. Molluscum contagiosum. NHS Website. Published February 18, 2020.
  2. CDC. Molluscum Contagiosum. CDC Website.
  3. CDC. Clinical Overview of Molluscum Contagiosum. Published April 15, 2025.
  4. CDC. Preventing Molluscum Contagiosum in Schools, Daycares, and Pools. Accessed July 2025.
  5. NHS Lothian. Molluscum Contagiosum – RefHelp.
  6. Meza-Romero R., Navarrete-Dechent C., Downey C. Molluscum contagiosum: an update and review of new perspectives in etiology, diagnosis, and treatment. Clin Cosmet Investig Dermatol. 2019;12:373–381.
Categories
Miscellaneous

The Risks Of Tanning Beds Explained

Tanning beds remain a popular method for achieving a bronzed appearance without relying on outdoor sunlight. However, these devices expose the skin to concentrated ultraviolet (UV) radiation, increasing the risk of premature ageing and skin cancer.

This article explains how tanning beds work, their associated health risks, and the safer, UV-free alternatives available for achieving a natural glow.

How Tanning Beds Function

Tanning beds use fluorescent lamps that emit ultraviolet light, primarily UVA, to stimulate melanin production and create the appearance of tanned skin [1]. These lamps expose nearly the entire body to radiation several times stronger than midday sunlight, delivering uniform but highly damaging UV exposure [6].

High-intensity UV radiation disrupts DNA repair, accelerates photoageing, and increases melanoma risk, even with short or infrequent sessions [2].

Understanding UV Light

Ultraviolet light falls between visible light and X-rays in wavelength and is divided into three main types:

UVA
Penetrates deeply into the dermis, producing a tan while damaging collagen and DNA. It is the dominant emission from tanning beds [1,6].

UVB
Acts mainly on the surface of the skin, causing sunburn and contributing to vitamin D synthesis. It is present in small amounts in tanning beds [4].

UVC
Completely absorbed by the ozone layer and absent from natural sunlight and tanning equipment.

The predominance of UVA exposure in tanning salons creates long-term damage without visible burning, falsely suggesting safety [6].

Health Risks Of Tanning Beds

Tanning bed use is strongly associated with premature ageing, skin cancer, and eye damage. The International Agency for Research on Cancer classifies tanning beds as Group 1 carcinogens, the same category as tobacco and asbestos [1,6].

Skin Cancers

Using tanning beds before age 35 increases melanoma risk by 75% [1,2]. Researchers estimate that approximately 6% of melanoma cases in the UK result from tanning bed exposure [2].

Even a few sessions can overwhelm DNA repair, leading to abnormal cell growth. Basal and squamous cell carcinomas, though less severe than melanoma, are also linked to regular use [2].

Premature Ageing

UVA light accelerates the breakdown of collagen and elastin in the skin. This results in wrinkles, loss of firmness, and uneven pigmentation appearing years earlier than expected [1,6].

Pseudoporphyria

Excessive UV exposure may trigger pseudoporphyria, a condition marked by skin fragility, blistering, and scarring [3]. These effects can persist after stopping tanning bed use, highlighting the long-term risks.

Eye Damage

Without protective eyewear, intense UV radiation can cause cataracts, retinal damage, and macular degeneration. Over time, this leads to impaired vision and eye discomfort [1,6].

Immune Suppression

Frequent UV exposure weakens the skin’s immune defence, making it more susceptible to infections and inflammatory conditions [1].

RiskSummary
Skin cancers75% increased melanoma risk with early use [1,2,5]
Premature ageingCollagen breakdown causes wrinkles and age spots [1,6]
PseudoporphyriaUV-induced blistering and scarring [3]
Eye damageCataracts and retinal harm from UV exposure [1,6]
Immune suppressionReduced defence against infection [1]

Table 1: Key risks associated with tanning bed use

Vitamin D & Tanning Beds

Claims that tanning beds boost vitamin D are misleading. Tanning lamps emit minimal UVB, the wavelength required for vitamin D production [4,5].

The NHS recommends obtaining vitamin D from foods such as oily fish, fortified dairy, or supplements, which are safe and effective [4,5].
The potential for melanoma far outweighs any supposed vitamin D benefit.

Addressing Skin Damage From Tanning Beds

Tanning bed use can lead to hyperpigmentation, dryness, and early signs of ageing. Managing these effects involves protective care and professional evaluation.

Key recovery steps:

  • Cool the skin: Use cold compresses or cool showers for relief.
  • Moisturise: Apply fragrance-free or aloe-based creams to hydrate.
  • Hydrate internally: Maintain adequate water intake for recovery.
  • Avoid further UV exposure: Protect the skin and discontinue tanning.

Clinical treatments such as light therapy, prescribed under medical supervision, differ entirely from UV tanning and may aid skin repair in specific cases [4].

Safer Tanning Alternatives

Modern alternatives achieve a golden tone without UV exposure:

Spray Tan Booths
These use dihydroxyacetone (DHA), a sugar-derived compound that reacts with the skin’s surface to create a temporary tan. The process is UV-free and fully customisable.

Self-Tanning Lotions
DHA-based lotions and mousses develop colour gradually, allowing control over depth and tone without radiation exposure.

Controlled Sunlight Exposure
For those preferring natural tanning, brief outdoor exposure (10–15 minutes) with broad-spectrum SPF 30+ sunscreen minimises harm while maintaining protection.

MethodDescriptionDurationUV Exposure
Spray tanDHA reacts with outer skin layer7–10 daysNone
Self-tanning lotionGradual colour development at home5–7 daysNone
Limited sunlightBrief daily exposure with SPF protectionVariableMinimal

Table 2: Comparison of UV-free tanning options

Monderma: Personalised Skincare Solutions

Monderma provides prescription-strength skincare designed by UK-registered prescribers and dispensed through a GPhC-regulated pharmacy. Treatments may help manage conditions such as hyperpigmentation, acne, or photoageing that develop following UV exposure.

Ingredients such as tretinoin and niacinamide support smoother texture and improved tone under professional guidance. Individuals with significant sun or tanning damage should seek medical advice before starting treatment.

Conclusion

Tanning beds expose the skin to intense UVA radiation that increases melanoma risk, accelerates visible ageing, and causes long-term cellular damage. Their use contributes to a measurable proportion of skin cancer cases in the UK [1,2,3]. Safer, UV-free options such as spray tanning and self-tanning lotions provide the desired glow without risk. Prioritising sun protection, avoiding tanning salons, and following evidence-based skincare can preserve long-term skin health.

To support skin recovery or prevent future UV damage, you can explore Monderma’s tailored consultation service. Share this article to raise awareness about safer alternatives to tanning.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. International Agency for Research on Cancer. IARC Strengthens Its Findings on Several Carcinogenic Personal Habits and Household Exposures. IARC Press Release No. 196, 2009.
  2. Boniol M., Autier P., Boyle P., Gandini S. Cutaneous Melanoma Attributable to Sunbed Use: Systematic Review and Meta-Analysis. BMJ, 2012; 345:e4757.
  3. Murphy G.M. Sunbed-Induced Pseudoporphyria. British Journal of Dermatology, 1989.
  4. NHS. Vitamin D. NHS UK, 2024.
  5. NICE. Vitamin D: Supplement Use in Specific Population Groups. 2017.
  6. Cancer Research UK. How Do Sunbeds Cause Skin Cancer? 2023.
Categories
Ingredients

Alpha Arbutin: A Gentle Skin Brightening Treatment

Alpha arbutin is a naturally derived skincare ingredient recognised for its ability to improve uneven skin tone and reduce the appearance of dark spots. Its gentle action makes it suitable for most skin types, including sensitive skin, offering a safer approach to achieving a brighter complexion.

This article explains how alpha arbutin works, its benefits compared with other brightening ingredients, and how it can form part of a professional skincare plan.

Understanding Alpha Arbutin

Alpha arbutin is a natural glycoside found in plants such as bearberry, cranberry, and blueberry. It combines glucose with a hydroquinone molecule but differs from hydroquinone in its gentler, non-irritating action.

It works by inhibiting tyrosinase, the enzyme responsible for melanin production. By reducing tyrosinase activity, alpha arbutin helps prevent the overproduction of pigment that causes dark spots and uneven tone.

Research in Biological & Pharmaceutical Bulletin found that alpha arbutin at concentrations between 0.1 and 1.0 mM reduced tyrosinase activity in human melanocytes without toxicity, outperforming kojic acid and vitamin C at equivalent doses [2].

How Alpha Arbutin Works

Melanin determines skin colour and is produced by melanocytes through a process controlled by tyrosinase. When this enzyme is overly active due to sun exposure, hormonal changes, or inflammation, hyperpigmentation develops.

Alpha arbutin selectively slows down tyrosinase, which helps reduce excessive pigment formation. Studies in Archives of Pharmacal Research confirmed that alpha arbutin lowered melanin production in laboratory models of stimulated pigmentation [4].

Benefits Of Alpha Arbutin

BenefitDescription
Reduces hyperpigmentationHelps fade dark spots and marks caused by sun exposure, acne, or hormonal imbalance when used consistently over several weeks [5].
Evens skin toneEncourages a balanced, radiant complexion.
Gentle for all skin typesWell tolerated and suitable even for sensitive skin.
Minimal side effectsRarely causes irritation or photosensitivity when used as directed.

Table 1: Benefits of alpha arbutin for skin tone and pigmentation balance

Alpha arbutin provides a well-rounded brightening approach that targets uneven tone while maintaining comfort and barrier health.

Comparing Alpha Arbutin To Other Skin Brighteners

Alpha Arbutin & Hydroquinone

Hydroquinone is a potent prescription skin lightening agent but may cause irritation or pigment rebound with long-term use. Alpha arbutin, a glycosylated derivative of hydroquinone, gently inhibits tyrosinase without cytotoxic effects, making it suitable for prolonged use [6].

Alpha Arbutin & Kojic Acid

Kojic acid is a fungal metabolite often used in brightening formulations but can trigger redness or irritation. Alpha arbutin generally offers better tolerance and has demonstrated greater effectiveness at lower concentrations in controlled studies [2].

Choosing The Right Alpha Arbutin Product

When selecting products, focus on concentration, formulation, and quality:

FactorRecommendation
Concentration1–2% alpha arbutin offers an effective balance of efficacy and safety [3].
FormulationLightweight serums allow better skin absorption.
Brand qualityChoose brands with pharmacist or clinician oversight for assured safety.

Table 2: Key product considerations when choosing alpha arbutin skincare

Daily use of sunscreen alongside alpha arbutin enhances results and prevents further pigmentation.

Monderma’s Custom Approach To Skin Brightening

Monderma offers personalised prescription skincare created by UK-registered prescribers and dispensed by a GPhC-registered pharmacy. Treatments are developed to address conditions such as hyperpigmentation, acne scarring, and uneven skin tone.

IngredientStrength RangeRole In Brightening
Alpha Arbutin1–2%Gently reduces melanin formation
Hydroquinone2–4%Prescription-only, inhibits pigment production
Azelaic Acid3–20%Balances tone and reduces inflammation
Tretinoin0.01–0.1%Promotes renewal for smoother, even texture
Niacinamide2–4%Supports barrier and reduces pigment transfer

Table 3: Active ingredients used in prescription brightening treatments

Each formula is assessed individually to ensure suitability for skin type, medical history, and treatment goals.

No independent clinical trials have been published on Monderma’s formulations.

Conclusion

Alpha arbutin offers a clinically supported, gentle way to brighten the skin and address pigmentation concerns. By inhibiting tyrosinase and limiting melanin overproduction, it can help create a more radiant, even complexion with regular use. Incorporating alpha arbutin with sun protection and consistent care supports visible improvement over time.

You can complete a free online consultation reviewed by a GPhC-registered prescriber to explore whether a prescription-strength formula could complement your skincare goals.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. Boo, Y.C. Arbutin as a skin depigmenting agent with antimelanogenic and antioxidant properties. Antioxidants (Basel), 2021; 10(7):1129.
  2. Sugimoto, K., et al. Inhibitory effects of alpha-arbutin on melanin synthesis in cultured human melanoma cells and a three-dimensional human skin model. Biological & Pharmaceutical Bulletin, 2004; 27(4):510–514.
  3. Sarkar, R., Arora, P., Garg, K.V. Cosmeceuticals for hyperpigmentation: what is available? Journal of Cutaneous and Aesthetic Surgery, 2013; 6(1):4–11.
  4. Lim, Y.J., et al. Inhibitory effects of arbutin on melanin biosynthesis of alpha-melanocyte stimulating hormone-induced hyperpigmentation in cultured guinea pig skin tissues. Archives of Pharmacal Research, 2009; 32(3):367–373.
  5. Schwartz, C., Jan, A., Zito, P.M. Hydroquinone. StatPearls, 2024.
Categories
Treatments

What Is Albinism? Genetic Condition Explained Clearly

Albinism is a rare inherited condition characterised by reduced or absent melanin in the skin, hair, and eyes. This pigment deficiency influences appearance, sun sensitivity, and vision.

This article explains what causes albinism, its main subtypes, and how those affected can protect their skin and wellbeing.

The Role Of Melanin

Melanin is a natural pigment made by melanocytes in the skin, hair, and eyes. It protects against ultraviolet (UV) radiation by absorbing and dispersing harmful rays that can cause sunburn or cell damage [1,7].

Genetic mutations that impair melanin synthesis lead to albinism. Without melanin, the skin is lighter, the eyes are more sensitive to sunlight, and the risk of UV-related health issues rises [1,7].

Melanin is also vital for visual development. Its absence can cause structural and functional eye changes, such as reduced acuity and light sensitivity [2,6,8].

Understanding melanin’s protective and developmental roles highlights why people with albinism require both sun protection and specialised eye care [1,7].

Types & Causes Of Albinism

Albinism occurs due to mutations in genes controlling melanin production. The two main forms are oculocutaneous albinism (OCA) and ocular albinism (OA) [1,2,8].

OCA affects skin, hair, and eyes, while OA primarily involves the eyes. OCA usually follows an autosomal recessive pattern, meaning both parents must carry the gene. OA is often linked to the X chromosome and more common in males [2,8].

Carriers usually have no symptoms but can pass the gene to their children. Genetic counselling can help families understand inheritance risks and available testing options [2,8].

Signs, Symptoms & Subtypes

Common Features

OCA presents with a range of visible and visual symptoms [2,8]:

  • Pale skin: Burns easily and does not tan, requiring careful sun protection [1,5,7]
  • Light hair: Colour ranges from white to light brown depending on residual melanin [1,2,8]
  • Visual impairments: Nystagmus, photophobia, and reduced vision are common [6,7,8]

These features can impact confidence, daily function, and independence, especially when vision support is limited [6,8].

OCA Subtypes

Each OCA subtype corresponds to specific gene mutations and melanin levels.

  • OCA1A: Complete absence of melanin
  • OCA1B: Partial melanin development over time [2,8]

Recognising subtypes supports accurate diagnosis and management planning.

SymptomDescription
Pale skinVery light skin that burns easily and does not tan [1,5,7]
Light hairRanges from white to light brown due to reduced melanin [1,2,8]
Visual impairmentsIncludes nystagmus, photophobia, and reduced acuity [6,7,8]

Table 1: Common symptoms and characteristics of OCA

Ocular Albinism (OA)

OA affects the eyes with minimal change to skin or hair colour. Symptoms often include [6]:

  • Nystagmus or involuntary eye movements
  • Photophobia or light sensitivity
  • Translucent irises that appear pink or red

Treatment focuses on improving visual comfort through corrective lenses, tinted glasses, or assistive devices [6].

Albinism Across Populations

Albinism affects individuals of all ethnic backgrounds. However, lighter pigmentation may cause social challenges and misunderstanding in some communities [3,5].

Education and awareness help correct myths and reduce stigma. Advocacy groups and public health initiatives play key roles in improving inclusion and protection [5].

Sun Protection & Sensitivity

Because melanin is reduced or absent, people with albinism are more prone to sunburn and UV damage [1,3,7]. Proper protection prevents photoaging and reduces cancer risk.

MeasureDescription
Broad-spectrum sunscreenSPF 30 or higher, reapplied regularly outdoors [1,3,7]
Protective clothingUse long sleeves, hats, and UV-filter sunglasses [1,3,7]
Seek shadeAvoid midday sun and limit prolonged exposure [1,3,7]

Table 2: Essential protective measures for albinism

Sun-safety education for children with albinism helps instil lifelong protective habits [1,3,7]. Schools, parents, and healthcare providers can support early awareness and ensure accessibility to suitable skincare and eye care [3,5].

Social Impact & Support

Living with albinism may involve emotional strain and social discrimination. Stigma can affect mental health and quality of life [5].

Empathy, education, and supportive communities foster acceptance. Counselling and peer networks can provide reassurance and strengthen self-esteem [5].

Albinism In Animals

Albinism also appears in animals, including reptiles, birds, and mammals. For example, albino pythons have distinctive pale skin and red eyes. Research into animal albinism enhances understanding of pigment biology and human genetics [5].

Promoting Awareness & Advocacy

Awareness efforts help build inclusive attitudes and improve health outcomes.

Key approaches include:

  • Education: Distributing factual information about albinism [5]
  • Advocacy: Supporting research and equality initiatives [5]
  • Community engagement: Hosting awareness events and media campaigns [5]

These actions promote empathy, challenge stereotypes, and protect human rights.

Skin Care For Albinism

Although skincare cannot change genetic pigment loss, it supports comfort and protection. Gentle, fragrance-free products, broad-spectrum sunscreen, and consistent moisturising maintain skin barrier strength [1].

Monderma provides prescription skincare for general information purposes only. These formulations are not indicated for genetic pigment disorders such as albinism but can support overall skin health under professional guidance.

Conclusion

Albinism is a lifelong genetic condition affecting pigmentation, vision, and social experience. Through education, advocacy, and strong sun protection, individuals with albinism can protect their health and wellbeing while promoting inclusion and awareness.

You can explore Monderma’s free online consultation to discover tailored skincare options for sensitive skin. Sharing this article helps raise awareness and understanding of albinism.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. NHS. Albinism. NHS Conditions, 2023.
  2. Grønskov K., Ek J., Brondum-Nielsen K. Oculocutaneous Albinism. Orphanet Journal of Rare Diseases, 2007; 2:43.
  3. Lund P.M., Taylor J.S. Lack of Adequate Sun Protection for Children with Oculocutaneous Albinism in South Africa. BMC Public Health, 2008; 8:225.
  4. British Association of Dermatologists. Squamous Cell Carcinoma. 2022.
  5. Marçon C.R., Maia M. Albinism: Epidemiology, Genetics, Cutaneous Characterisation, Psychosocial Factors. Anais Brasileiros de Dermatologia, 2019; 94(5):503-520.
  6. Kruijt C.C., de Wit G.C., Bergen A.A., Florijn R.J., Schalij-Delfos N.E., van Genderen M.M. The Phenotypic Spectrum of Albinism. Ophthalmology, 2018; 125(12):1953-1960.
  7. Brenner M., Hearing V.J. The Protective Role of Melanin Against UV Damage in Human Skin. Photochemistry and Photobiology, 2008; 84(3):539-549.
  8. MedlinePlus. Oculocutaneous Albinism. Genetics Home Reference, 2021.
Categories
Miscellaneous

How Sleep Boosts Your Night Skincare Routine

Sleep is one of the most effective natural tools for skin renewal. During rest, the body enters a restorative phase where cellular repair peaks, circulation improves, and collagen synthesis strengthens the skin barrier. Understanding this process helps achieve visibly smoother, firmer, and more radiant skin over time.

This article explains how sleep enhances skin repair, which skincare steps work best overnight, and how personalised treatment can maximise your results.

Why Sleep Is Essential For Skin Health

Quality sleep allows the skin to recover from daily stress and environmental exposure. As circulation increases, oxygen and nutrients reach the skin more efficiently, stimulating regeneration. Collagen production also rises, supporting firmness and reducing fine lines [1,2].

Insufficient sleep can weaken the skin barrier, increase inflammation, and accelerate visible ageing [3,4]. Consistent rest remains one of the most effective ways to maintain healthy, resilient skin.

How Sleep Affects Hormones & Skin

During sleep, hormonal balance is restored. Cortisol levels fall, which reduces inflammation and helps preserve barrier function. High cortisol can lead to dryness, dullness, and early signs of ageing. Achieving seven to nine hours of rest nightly helps maintain optimal hormone levels [8].

Experts often describe sleep as the body’s natural reset, giving skin the time and resources needed to repair and strengthen.

The Role Of Collagen In Skin Repair

Collagen is a structural protein that keeps the skin firm and smooth. Research shows collagen synthesis increases at night, improving elasticity and softening fine lines [2,3]. When sleep is restricted to about four hours per night, collagen production falls and the skin can lose bounce and clarity [9].

Restoring proper sleep patterns allows collagen to rebuild, creating a visibly refreshed complexion.

Skincare Products To Enhance Sleep Benefits

A well structured night routine supports the body’s natural repair rhythm. Products rich in hydrating and restorative ingredients help the skin recover more effectively while you rest.

Collagen Face Masks & Creams

Collagen masks infuse moisture and may support elasticity, particularly those formulated with hydrolysed or nano collagen. Eye masks can hydrate delicate areas.

Although collagen creams provide surface hydration, the molecules are usually too large to penetrate deeply. For stronger results, prescription ingredients that stimulate collagen within the skin can be more effective.

Hydrating Serums & Moisturisers

A hydrating serum helps lock in moisture and supports the skin barrier. Applying it before a night cream aids overnight renewal. Consistent hydration reduces transepidermal water loss and supports smoother texture [12].

Sleep Masks & Accessories

Silk sleep masks create a dark, comfortable environment that supports deeper rest and reduces friction on the skin. Lip masks prevent dryness, while a supportive pillow can aid circulation. Better sleep quality enhances nutrient delivery and recovery [1].

Night Skincare Routine For Optimal Results

A calm, consistent evening routine enhances the benefits of rest. Begin with a gentle cleansing balm to remove impurities. Apply an active serum, such as one containing collagen or niacinamide, then seal with a nourishing night cream. Use a targeted face mask weekly for additional renewal.

What To Expect From Better Sleep & Skincare

With seven to nine hours of consistent sleep, collagen formation peaks, fine lines soften, and overall tone can improve within weeks [3].

AspectBenefit Of SleepOutcome Without Sleep
Collagen ProductionBoosts assembly and elasticityReduced firmness and more wrinkles
Blood FlowImproves complexion and repairDull and uneven tone
Hormonal BalanceRegulates cortisol and protects barrierIncreased inflammation

Table 1: Sleep supports key skin functions that maintain radiance and firmness

Monderma’s Personalised Custom Formula

Monderma’s prescription strength skincare is designed by UK registered clinicians and dispensed by a GPhC regulated pharmacy. Each formulation supports the skin’s nightly repair phase through clinically recognised actives.

IngredientStrengthDescriptionHow It Supports Overnight Repair
Adapalene0.1 to 0.3%Vitamin A retinoidIncreases cell turnover for faster renewal overnight
Azelaic Acid3 to 20%Naturally derived dicarboxylic acidCalms inflammation and supports barrier recovery during rest [10]
Hydroquinone2 to 4%Prescription only pigment inhibitorReduces melanin formation for clearer tone under supervision [11]
Niacinamide2 to 4%Vitamin B3 derivativeEnhances hydration and reinforces the barrier overnight [12]
Tretinoin0.01 to 0.1%Prescription retinoidSupports collagen synthesis and renewal during sleep [13]

Table 2: Clinical actives timed with sleep can enhance natural overnight repair

Additional Tips For Healthy Skin

Nutrition and lifestyle habits strengthen the effects of sleep on skin health. A diet rich in antioxidants helps defend against oxidative stress, while adequate hydration supports cell renewal. Relaxation techniques such as gentle yoga or breathing exercises promote deeper rest, further supporting barrier recovery.

Conclusion

Sleep is a powerful ally for skin renewal, supporting collagen, hydration, and hormonal balance. Combined with a tailored night routine and professional skincare guidance, it can deliver visible improvements in clarity, texture, and tone.

Start a free online consultation reviewed by one of our GPhC-registered prescribers to explore a prescription-strength formula that complements your skin’s overnight repair.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. Healthline, 6 Ways to Maximize Your Beauty Sleep for #WokeUpLikeThis Skin, 2018.
  2. Nature Cell Biology, Circadian Control of the Secretory Pathway Maintains Collagen Homeostasis, 2020.
  3. Jang, S., et al. A Study of Skin Characteristics with Long Term Sleep Restriction in Korean Women, 2019.
  4. Vujevich Dermatology, Beauty Sleep: How Sleep Affects Skin, 2019.
  5. Healthline, Do Not Sleep on the Importance of Beauty Rest, 2022.
  6. Sleep Foundation, Beauty Sleep: Why Rest and Relaxation Impact Appearance, 2023.
  7. Monderma, Personalised Custom Formula, 2025.
  8. Kahan, V., et al. Can Poor Sleep Affect Skin Integrity? PubMed, 2010.
  9. Holding, B.C., et al. The Effect of Sleep Deprivation on Facial Appearance, 2019.
  10. Banner Health, The Different Skin Benefits of Azelaic Acid, 2022.
  11. Healthline, Everything You Need to Know About Hydroquinone, 2018.
  12. La Roche-Posay, What Does Niacinamide Do: Unveiling Its Skin Benefits, 2024.
  13. Academic All Derm, Tretinoin Cream: The Ultimate Guide, 2023.
Categories
Ingredients

Tretinoin Results: Timeline, Expected Effects & Use

Tretinoin is a clinically proven topical treatment that improves acne, skin texture, and visible signs of ageing. As a form of vitamin A, it accelerates cell turnover, helping to reveal clearer, smoother skin with consistent use.

This article explains how tretinoin works, what results to expect over time, and how to maximise its benefits safely.

Understanding Tretinoin & How It Works

Tretinoin is available as a cream, gel, or lotion and is applied in a pea-sized amount once daily. It is most often prescribed for acne but also helps reduce fine lines, sun damage, and uneven tone [1,2,3].

As a derivative of vitamin A, tretinoin promotes faster skin cell renewal and prevents clogged pores. Research shows that it increases epidermal proliferation and collagen synthesis, leading to healthier, smoother skin [2,3].

Starting Tretinoin: What To Expect

Mild irritation is common when beginning tretinoin treatment. Temporary redness, peeling, and dryness may occur as the skin adjusts [4]. This is known as the “retinisation” period.

Some individuals also experience an initial acne flare, sometimes called a purge phase, as pores begin to clear [8]. The NHS notes that these effects typically settle as skin tolerance builds [4].

To ease adjustment:

  • Apply every other night for the first two weeks
  • Use a moisturiser after application
  • Avoid harsh exfoliants or alcohol-based products

Tretinoin Results Timeline

Visible results develop gradually with consistent use. Most improvements appear between 8 and 12 weeks, with full results after several months of regular application.

Time PeriodPhaseWhat To Expect
Weeks 1–4Adjustment PhaseRedness, peeling, or mild purging as skin adapts [4,8].
Weeks 4–8Visible Changes BeginTexture begins to smooth, breakouts start to reduce [5,7].
Weeks 8–12Noticeable ResultsFewer acne lesions and lighter dark spots [3,6].
After 12 WeeksLong-Term BenefitsClearer skin, even tone, and improved firmness [6,9].

Table 1: General tretinoin results timeline and expected improvements

Patience is essential. Studies show that acne lesions may decrease by up to 40% after 12 weeks of tretinoin use [11], with ongoing improvement for pigmentation and fine lines beyond three months.

Tretinoin Effects & Benefits

Tretinoin provides multiple clinically supported benefits for acne and photoaged skin.

Reduces Acne & Prevents Breakouts

Tretinoin helps keep pores clear, reducing both inflammatory and non-inflammatory acne. It also prevents new blockages from forming. NICE recommends topical retinoids, including tretinoin, as a first-line therapy for mild to moderate acne [10].

Improves Texture & Tone

By stimulating cell turnover, tretinoin smooths rough texture and fades dark marks caused by post-inflammatory pigmentation [6,9]. Consistent use helps create a brighter, more even complexion.

Minimises Fine Lines & Early Ageing

Tretinoin stimulates collagen production, softening fine lines and reducing visible signs of photoageing [6]. Long-term use can improve firmness and elasticity, though deep wrinkles may require additional treatments.

BenefitMechanismEvidence
Acne reductionUnclogs pores and reduces inflammationNICE, 2021 [10]
Smoother textureAccelerates epidermal renewalWeiss et al., 1988 [3]
Fades pigmentationPromotes exfoliation and turnoverBulengo-Ransby et al., 1993 [9]
Reduces fine linesBoosts collagen synthesisSitohang et al., 2022 [6]

Table 2: Clinical benefits of tretinoin and supporting evidence

Tips For Success With Tretinoin

A gentle, consistent routine helps maximise results and minimise irritation.

  • Start slowly: Use a low strength such as 0.025% and increase as tolerated [4,8].
  • Moisturise regularly: Apply a non-comedogenic moisturiser after tretinoin to prevent dryness [4,8].
  • Use sunscreen daily: Broad-spectrum SPF 30 or higher is essential, as tretinoin increases sun sensitivity [2,7].
  • Avoid harsh actives: Do not mix tretinoin with exfoliating acids until tolerance builds.
  • Be consistent: Results rely on regular use over several months.

Monderma’s Custom Formula With Tretinoin

Monderma offers prescription-strength skincare tailored by UK-registered prescribers and dispensed through a GPhC-registered pharmacy.

Each formula is customised following clinical consultation and may include tretinoin alongside other evidence-based ingredients to target acne, ageing, and uneven tone.

IngredientStrengthDescriptionClinical Benefit
Tretinoin0.01–0.1%Prescription vitamin A derivativeBoosts cell turnover and smooths texture
Azelaic Acid5–20%Naturally derived anti-inflammatoryReduces pigmentation and inflammation
Niacinamide2–4%Vitamin B3 derivativeSupports barrier and brightens tone
Adapalene0.1–0.3%Topical retinoid alternativeImproves acne with less irritation

Table 3: Key ingredients used in Monderma’s prescription formulas

Conclusion

Tretinoin remains one of the most effective treatments for acne, pigmentation, and early skin ageing. Results develop gradually, with visible improvement typically within 8 to 12 weeks and continued benefits with ongoing use.

Professional guidance ensures safe, optimised results and long-term skin health. Monderma’s prescription treatments, created by UK-registered prescribers, offer tailored solutions to support your journey toward clearer, smoother skin.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. Kligman, A.M. et al. Topical Tretinoin for Photoaged Skin. Journal of the American Academy of Dermatology, 1986, 15(4):836–859.
  2. Mayo Clinic. Tretinoin (Topical Route). 2025.
  3. Weiss, J.S., Ellis, C.N., Headington, J.T., Tincoff, T., Hamilton, T.A., & Voorhees, J.J. Topical Tretinoin Improves Photoaged Skin: A Double-blind Vehicle-Controlled Study. JAMA, 1988; 259(4):527–532.
  4. NHS. Acne Treatment. 2023.
  5. UK Meds. How Long Does Tretinoin Take to Work? 2025.
  6. Sitohang, I.B., Makes, W.I., Sandora, N., & Suryanegara, J. Topical Tretinoin for Treating Photoaging: A Systematic Review of Randomized Controlled Trials. International Journal of Women’s Dermatology, 2022; 8(2):e015.
  7. Miiskin. How Long Does Tretinoin Take To Work for Acne and Wrinkles? 2025.
  8. Miiskin. What Is the Tretinoin Purge? We Asked a Derm. 2025.
  9. Bulengo-Ransby, S.M. et al. Topical Tretinoin (Retinoic Acid) Therapy for Hyperpigmented Lesions. Archives of Dermatology, 1993.
  10. NICE. Acne Vulgaris: Management. NG198, 2021.
  11. Haider, A., & Shaw, J.C. Treatment of Acne Vulgaris. JAMA, 2004; 292(6):726–735.
Categories
Treatments

Papulopustular Rosacea Symptoms & Best Care Tips

Papulopustular rosacea is a common subtype of rosacea that causes facial redness, inflammation, and acne-like bumps. Understanding its symptoms and treatment options helps manage this chronic condition effectively and improve skin comfort.

This article explains what papulopustular rosacea is, its main symptoms, and the most effective evidence-based treatments, alongside lifestyle and skincare advice.

What Is Papulopustular Rosacea

Papulopustular rosacea is a chronic inflammatory skin condition often mistaken for acne. It presents as red bumps and pus-filled lesions on the face, commonly affecting the cheeks, chin, nose, and forehead [6].

This subtype can occur in all skin tones and genders but is more frequent in adults with lighter complexions [5]. Along with erythematotelangiectatic, phymatous, and ocular rosacea, it is one of four recognised forms of rosacea.

Persistent redness, visible capillaries, and a burning or stinging sensation are hallmark features. Many individuals also experience emotional distress due to changes in appearance [1].

Symptoms Of Papulopustular Rosacea

Recognising symptoms early supports accurate diagnosis and appropriate care.

SymptomDescription
Persistent facial rednessContinuous redness, appearing pink or flushed in lighter skin and dusky brown in darker skin tones [5].
Red bumps (papules)Small, raised, inflamed spots that may feel tender [6].
Pus-filled bumps (pustules)White or yellow lesions resembling acne [6].
Visible blood vessels (telangiectasias)Small red lines caused by dilated capillaries [6].
Burning or stinging sensationsSkin discomfort often described as heat or irritation [1].
Dry, rough textureThe skin may feel tight or scaly [1].

Table 1: Common symptoms of papulopustular rosacea and their characteristics.

If these symptoms appear, it is important to consult a dermatologist. Rosacea can mimic acne, dermatitis, or perioral inflammation, making professional evaluation essential.

The Best Treatments For Papulopustular Rosacea

Rosacea management requires a combination of topical therapy, oral medication, and supportive skincare. Treatment choice depends on severity, triggers, and response over time.

Topical Treatments

Topical therapies are the first step in controlling inflammation and redness.

  • Metronidazole Cream: This antibiotic reduces inflammation and is effective in decreasing papules and pustules. A Cochrane review confirmed its superiority to placebo [2].
  • Azelaic Acid: Proven to reduce swelling, redness, and lesions, supported by high-certainty evidence for rosacea [3,12].
  • Ivermectin Cream: Acts on inflammation and Demodex mites. Studies show greater lesion reduction and patient satisfaction compared with metronidazole [7,8].
  • Tretinoin: A vitamin A derivative that promotes skin renewal. It may help improve texture but requires caution due to possible irritation [2].

Oral Medications

Oral therapy is often recommended for moderate or severe rosacea.

  • Antibiotics: Low-dose doxycycline reduces inflammation and lesion count. NICE guidelines recommend tetracyclines, including doxycycline, as first-line systemic therapy [4].
  • Isotretinoin: Considered for resistant cases under specialist supervision. It decreases oil production and inflammation but requires careful monitoring due to potential side effects [9].

Laser & Light Therapies

Laser and light-based procedures target persistent redness and visible blood vessels.

  • Intense Pulsed Light (IPL): Helps reduce redness and improve skin texture by targeting vascular structures [10,11].
  • Pulsed Dye Laser: Effective for telangiectasias and chronic redness but not for papules or pustules. Availability and cost may vary [10].
Treatment TypeBenefitTimeframeConsideration
Topical Azelaic AcidReduces redness and swelling8–12 weeksMild tingling may occur
Ivermectin CreamReduces inflammation and mites12–16 weeksExcellent tolerability
Doxycycline (oral)Controls moderate to severe lesions8–16 weeksPrescription required
IPL TherapyImproves redness and tone4–8 sessionsPrivate treatment
IsotretinoinFor resistant casesVariableRequires medical supervision

Table 2: Common rosacea treatments and their main benefits

Lifestyle Changes & Rosacea Management

Simple adjustments in daily habits can complement clinical treatment and reduce flare frequency.

Diet & Nutrition

A balanced, anti-inflammatory diet may improve skin comfort. Include foods rich in omega-3 fatty acids, antioxidants, and vitamins. Limiting alcohol, spicy foods, and very hot drinks may reduce flare-ups [6].

Stress & Emotional Balance

Stress is a well-known trigger. Relaxation techniques such as meditation, yoga, or breathing exercises can help stabilise flare cycles [6].

Skin Hydration

Hydration supports the skin barrier, improving tolerance to topical treatments. Drink adequate water and use moisturisers with ceramides or hyaluronic acid [6].

Monderma’s Personalised Approach To Rosacea

Monderma provides personalised, prescription-strength formulations created by UK-registered prescribers and dispensed by a GPhC-registered pharmacy.

Each rosacea treatment is tailored following an online clinical consultation. Ingredients such as azelaic acid and ivermectin help reduce redness, inflammation, and flare frequency.

IngredientStrengthDescriptionRole In Rosacea Management
Azelaic Acid10–20%Naturally derived anti-inflammatoryReduces swelling and redness
Ivermectin1%Antiparasitic and anti-inflammatoryTargets Demodex and reduces lesions
Niacinamide2–4%Vitamin B3 derivativeStrengthens barrier and calms irritation
Tretinoin0.01–0.05%Vitamin A retinoidSupports texture and cell renewal

Table 3: Key ingredients in Monderma’s prescription rosacea treatments

Conclusion

Papulopustular rosacea is a treatable skin condition that benefits from consistent care, prescription-based treatment, and targeted skincare. Combining topical therapy, oral medication, and lifestyle changes helps restore comfort and confidence.

Professional assessment remains essential for accurate diagnosis and safe treatment selection. Monderma’s tailored prescription skincare offers expert-guided solutions for managing rosacea symptoms effectively and maintaining long-term skin balance.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. McGregor S.P., Alinia H., Snyder A., Tuchayi S.M., Fleischer A., Feldman S.R. A Review of the Current Modalities for the Treatment of Papulopustular Rosacea. Dermatol Clin. 2018;36(2):135–150.
  2. van Zuuren E.J., Fedorowicz Z., Carter B., van der Linden M.M., Charland L. Interventions for Rosacea. Cochrane Database Syst Rev. 2015;2015(4):CD003262.
  3. van Zuuren E.J., Fedorowicz Z., Tan J., et al. Interventions for Rosacea Based on the Phenotype Approach: An Updated Systematic Review. Br J Dermatol. 2019;181(1):65–79.
  4. National Institute for Health and Care Excellence (NICE). Rosacea – Management. Updated October 2021.
  5. American Academy of Dermatology. Rosacea: Signs and Symptoms.
  6. Healthline. Papulopustular Rosacea: Symptoms, Triggers, Treatment.
  7. Healthline. What to Know About Ivermectin for Rosacea: Effectiveness, Side Effects, and Safety.
  8. AAFP. Ivermectin 1% Cream (Soolantra) for Inflammatory Lesions of Rosacea.
  9. Assiri A. et al. Efficacy of Low-Dose Isotretinoin in the Treatment of Rosacea.
  10. Schroeter C.A., Haaf-von Below S., Neumann H.A. Effective Treatment of Rosacea Using Intense Pulsed Light Systems. Dermatol Surg. 2005;31(10):1285–1289.
  11. King S. et al. A Systematic Review to Evaluate the Efficacy of Azelaic Acid in the Management of Acne, Rosacea, Melasma and Skin Aging. PubMed.
  12. Mazurek K. et al. Dermocosmetics Containing Azelaic Acid for Rosacea Management. J Cosmet Dermatol. 2016;15(4):393–399.
Categories
Miscellaneous

How To Safely Achieve That Bronze Skin Tan This Season

Exposure to ultraviolet (UV) rays stimulates melanin production, creating a tanned appearance. However, tanning results from DNA damage, meaning a completely safe natural tan is impossible [1]. Even limited exposure can accelerate ageing and increase risks of hyperpigmentation and skin cancer [2,4,5].

This article explains how to tan more safely, protect your skin, and achieve a golden glow through evidence-based methods and sunless alternatives.

Fitzpatrick Skin Types & Tanning Responses

The Fitzpatrick scale classifies skin based on its reaction to UV rays. Understanding your skin type supports safer tanning practices [3].

Fitzpatrick Skin TypeDescriptionBurning TendencyTanning ResponsePhotoprotection Needs
Type IVery fairAlways burnsNever tansStringent photoprotection to prevent damage
Type IIFairBurns easilyTans minimallyHigh SPF and gradual exposure
Type IIIMediumBurns moderatelyTans graduallyBroad-spectrum sunscreen for even tone
Type IVOliveBurns minimallyTans easilyRegular protection for long-term health
Type VBrownRarely burnsTans deeplySPF to prevent hyperpigmentation
Type VIDarkNever burnsTans profoundlyUV protection to maintain even tone

Table 1: Fitzpatrick skin types and tanning responses

Photoprotection & Safe Tanning

Photoprotection is the foundation of safe tanning. Physical barriers and sunscreen together reduce but do not eliminate UV-related risks.

Physical Protection

Physical barriers remain the most effective form of defence.

  • Avoid sun exposure between 11:00 and 15:00 when UV rays are strongest [5].
  • Wear long sleeves, wide-brimmed hats, and UV-protective fabrics.
  • Seek shade whenever possible during outdoor activities.

Sunscreen Use

Sunscreen protects against UVA (ageing) and UVB (burning) rays. Both reflective and absorbent types are beneficial.

  • Choose a broad-spectrum SPF 15–30 containing zinc oxide or avobenzone [6].
  • Apply generously 30 minutes before exposure and reapply every two hours or after swimming.
  • SPF 30 offers stronger protection for daily use.

Note: Sunscreen alone does not completely prevent skin cancer. It should always be combined with protective clothing and shade [7].

Approaching Tanning With Caution

Some may still wish to achieve a sun-kissed look. While UV tanning always carries some risk, following cautious routines helps minimise harm.

Optimal Timing

Limit exposure to early morning or late afternoon. Avoid tanning between 11:00 and 15:00 when rays are most intense [5].

Gradual Exposure

Start with 5–10 minutes per session. Increase gradually while monitoring for redness or tightness. Overexposure heightens DNA damage and photoageing [1].

Hydration For Skin Health

Hydrated skin tans more evenly. Drink water regularly and use moisturisers with aloe vera or hyaluronic acid to maintain suppleness [8].

Tanning Tips For Different Skin Types

Tailoring your approach according to skin type helps reduce irritation and uneven tone.

How To Tan Pale Skin

  • Begin with SPF 30 or higher, never below SPF 15 [6].
  • Limit exposure to 5–10 minutes per session.
  • Use wide-brimmed hats and sunglasses to protect sensitive areas.

Olive Skin Tanning

  • Use SPF 15–30 with consistent reapplication.
  • Hydrate with shea butter or niacinamide-rich products to preserve softness.

Bronze & Darker Skin

  • Maintain SPF 15–30 to prevent hyperpigmentation.
  • Aloe vera-based moisturisers enhance radiance and even tone.

Maintaining Your Tan

A tan, whether natural or sunless, requires consistent care to maintain an even glow.

  • Moisturise Daily: Use nourishing ingredients such as shea butter and aloe vera.
  • Use Lukewarm Water: Hot water can strip natural oils and shorten tan duration.
  • Exfoliate Weekly: Gently buff away dead skin to maintain smooth, radiant colour.

Safer Alternatives: Sunless Tanning Products

Sunless tanning products provide a golden tone without UV exposure. These include sprays, mousses, and lotions that react with skin surface proteins to create a bronzed appearance [8].

Product TypeBenefitApplication Tip
Skin Tan SprayEven, streak-free coverageExfoliate before use and apply with a mitt
Gradual Tan LotionBuildable colour and hydrationApply daily until desired tone achieved
Tanning MousseQuick-drying natural glowBlend evenly using circular motions

Table 2: Types of sunless tanning products and benefits

For the most natural finish, select cruelty-free products with hydrating ingredients such as vitamin E and aloe vera.

Debunking Myths: Tanning & Vitamin D

A common misconception is that tanning is necessary for vitamin D. Research shows this is untrue.

  • Skin stops vitamin D production after 15–20 minutes of UVB exposure [9].
  • UVA rays, responsible for tanning, do not produce vitamin D [9].
  • Sunscreen use does not significantly reduce vitamin D levels [10].
  • Supplements offer a safe, effective way to maintain adequate vitamin D [11].

Monderma: Personalised Skincare For Sun-Exposed Skin

Monderma provides prescription-strength formulations developed by UK-registered prescribers and dispensed by a GPhC-registered pharmacy. Treatments include ingredients such as niacinamide and azelaic acid to support skin recovery from photoageing and uneven pigmentation.

Each formula is tailored following an online consultation to restore balance, clarity, and long-term skin health.

Conclusion

While natural tanning always involves UV-induced damage, combining physical protection, broad-spectrum sunscreen, and sunless tanning offers a safer path to a golden glow.

For expert skincare advice and personalised protection plans, start a free consultation with Monderma to maintain radiant, healthy-looking skin without compromising safety.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. AIM at Melanoma Foundation. Outdoor tanning.
  2. Cancer Research UK. How do sunbeds cause skin cancer?
  3. DermNet NZ. Skin phototype (Fitzpatrick skin type).
  4. NHS. Skin cancer (non-melanoma). 2023.
  5. Skin Cancer Foundation. UV radiation & Your Skin.
  6. Skin Cancer Foundation. Sunscreen.
  7. Institute of Cancer Research. New clues to skin cancer development show sunscreen is not enough. 2013.
  8. Skin Cancer Foundation. Sunless Tanning Explained.
  9. Wacker M, Holick MF. Sunlight and Vitamin D: A global perspective for health. Int J Environ Res Public Health. 2013.
  10. The Conversation. Sunscreen won’t stop you making vitamin D. 2024.
  11. NHS. Vitamin D. 2024.
Categories
Ingredients

Azelaic Acid Benefits: How Effective Is It Really?

The Science Behind Azelaic Acid

Azelaic acid is a dicarboxylic acid that penetrates the skin and blocks tyrosinase, an enzyme that triggers melanin production. This can help to fade dark spots and even skin tone.

In this article, we discuss findings including from a 2017 review that confirmed azelaic acid’s anti-inflammatory and antimicrobial actions, supporting its use for acne and rosacea [1].

Natural Sources Of Azelaic Acid

Azelaic acid occurs naturally in grains such as barley, wheat, and rye, and is also produced by a type of skin yeast known as Malassezia furfur [2].

Its natural origin appeals to individuals who prefer sustainable and well-tolerated skincare ingredients.

Azelaic Acid In Skincare Formulations

Due to its broad benefits, azelaic acid features in creams, gels, and foams for acne, rosacea, and pigmentation.

A 2003 study found that 15% azelaic acid gel was more effective than metronidazole for rosacea management [3]. Its versatility makes it valuable in dermatology and cosmetic formulations.

BenefitHow It WorksEvidenceAdditional Notes
Reduces AcneTargets acne-causing bacteria and inflammation20% cream reduced acne lesions comparably to tretinoin after 6 months [4]Works with benzoyl peroxide or AHA
Evens Skin ToneInhibits melanin productionComparable to hydroquinone in some trials [5]Brightens gradually and safely
Treats RosaceaReduces redness and lesion count15% gel with doxycycline reduced lesions by ~50% [13]Outperformed placebo [6]
Gentle On SkinMild on sensitive skinMinimal, transient irritation with 15% foam [7]Suitable for most skin types

Table 1: Azelaic acid’s main skincare benefits and evidence

How To Use Azelaic Acid

Introducing azelaic acid gradually allows the skin to adapt. It is available in multiple formulations to suit individual skin types.

Azelaic Acid Forms: Creams, Gels & Foams

  • Creams: Hydrate dry skin while delivering active ingredients.
  • Gels: Lightweight, ideal for oily or combination skin.
  • Foams: Absorb easily with excellent tolerability.

A 2018 study showed 15% azelaic acid foam improved acne in 84% of patients after 16 weeks [7].

Adding Azelaic Acid Into Your Routine

  • Start with 10% strength once daily, ideally at night
  • After one month, increase to twice daily if tolerated
  • Follow with a moisturiser to prevent dryness

Consistency is essential for visible results.

Combining Azelaic Acid With Other Ingredients

Azelaic acid pairs well with several actives to address multiple concerns simultaneously.

IngredientBenefitUsage Tip
NiacinamideReduces inflammation and evens toneSafe to use together or alternate days [11]
RetinolImproves texture and acneUse azelaic acid in the morning, retinol at night [12]
Vitamin CBrightens and fades dark spotsApply vitamin C in the morning, azelaic acid at night [13]

Table 2: Synergistic skincare combinations with azelaic acid

Azelaic Acid For Different Skin Concerns

Azelaic acid offers multi-targeted benefits across acne, rosacea, and hyperpigmentation.

Skin ConcernKey ActionEvidenceTimeframe
AcneClears bacteria and unclogs pores20% cream matched tretinoin efficacy [4]4–8 weeks
RosaceaCalms redness and inflammation15% gel reduced lesion count by ~50% [13]8–12 weeks
HyperpigmentationInhibits melanin production20% cream improved melasma after 15 weeks [12]Several months

Table 3: Clinical outcomes for different skin concerns

Azelaic Acid Side Effects

Azelaic acid is generally well-tolerated, though mild reactions can occur during early use.

  • Tingling or burning: Temporary, improves with continued use. Apply every other night until tolerance builds.
  • Dryness or peeling: Use a gentle cleanser and hydrating moisturiser.
  • Irritation: Rare; reduce frequency or seek professional guidance if persistent.

Monderma’s Custom Formula With Azelaic Acid

Monderma offers prescription-strength formulations created by UK-registered prescribers and dispensed by a GPhC-registered pharmacy. Each treatment is personalised following clinical assessment.

IngredientStrengthDescriptionSkin Benefit
Azelaic Acid3–20%Naturally derived dicarboxylic acidReduces melanin and inflammation
Adapalene0.1–0.3%Vitamin A derivativePromotes cell renewal and unclogs pores
Niacinamide2–4%Vitamin B3 derivativeSupports barrier and tone balance
Tretinoin0.01–0.1%Prescription retinoidIncreases turnover and smooths texture

Table 4: Key ingredients in Monderma’s custom formulas

Conclusion

Azelaic acid is a clinically proven, gentle yet effective treatment for acne, rosacea, and hyperpigmentation. Its anti-inflammatory, antimicrobial, and pigment-balancing properties make it suitable for everyday use, even on sensitive skin.

You can complete a free online consultation reviewed by a GPhC-registered prescriber to see if a prescription-strength formula containing azelaic acid is right for your skin.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. Del Rosso J.Q. Azelaic Acid Topical Formulations: Differentiation of 15% Gel and 15% Foam. J Clin Aesthet Dermatol. 2017;10(3):37–40.
  2. Rangasamy D., Sebastian S.R. Bioprospecting Yeast Malassezia furfur: A Source of Azelaic Acid. J Drug Alcohol Res. 2023;12(10):105121.
  3. Elewski B.E. et al. Comparison of 15% Azelaic Acid Gel and 0.75% Metronidazole Gel in Papulopustular Rosacea. Arch Dermatol. 2003;139(11):1444–1450.
  4. Katsambas A. et al. 20% Azelaic Acid Cream in Acne Vulgaris vs. Tretinoin. Acta Derm Venereol Suppl. 1989;143:35–39.
  5. Bergman D., Luke J. Azelaic Acid. J Drugs Dermatol. 2017;16(5):475–480.
  6. Liu R.H. et al. Azelaic Acid in Rosacea: Systematic Review of RCTs. Arch Dermatol. 2006;142(8):1047–1052.
  7. Hashim P.W. et al. Efficacy and Safety of Azelaic Acid 15% Foam in Acne. J Drugs Dermatol. 2018;17(6):641–645.
  8. Hoffman L.K. et al. Azelaic Acid 15% Foam for Truncal Acne. J Drugs Dermatol. 2017;16(6):534–538.
  9. Thach T.T. et al. Azelaic Acid Induces Mitochondrial Biogenesis. Front Physiol. 2020;11:329.
  10. Sauer N. et al. Multiple Uses of Azelaic Acid in Dermatology. Postepy Dermatol Alergol. 2024;40(6):716–724.
  11. Feng X. et al. Azelaic Acid: Mechanisms of Action and Clinical Applications. Front Cell Infect Microbiol. 2024;14:11512533.
  12. Mazurek K. et al. Dermocosmetics Containing Azelaic Acid for Melasma. J Cosmet Dermatol. 2016;15(4):393–399.
  13. Draelos Z.D. Azelaic Acid Foam 15% in Rosacea. Cutis. 2013;92:306–310.
Categories
Treatments

Psoriasis Risk Factors Including Belly Fat Impact

Psoriasis is a chronic inflammatory skin condition affecting millions worldwide, characterised by red, scaly patches that impact comfort and confidence. A 2025 study from King’s College London and ScienceDaily identified a key connection: central body fat, particularly around the abdomen, may increase psoriasis risk, with a stronger effect seen in women [1,3,4].

This article highlights how fat distribution, not just total body weight, can influence inflammatory skin disorders. Understanding this link helps shape new approaches combining lifestyle, inflammation management, and skincare for long-term control.

Key Findings On Psoriasis & Belly Fat

FindingDetails
Central Fat PriorityAbdominal fat shows a stronger connection to psoriasis risk than total body fat [4].
Gender DisparityWomen with higher abdominal fat face a greater psoriasis risk than men [4].
Inflammation TriggerExcess belly fat increases systemic inflammation, worsening inflammatory skin conditions [4].

Table 1: Central fat plays a key role in psoriasis risk, especially among women

“Where fat is stored in the body matters when it comes to psoriasis risk. Central fat, especially around the waist, seems to play a key role.”
— Ramessur et al., Journal of Investigative Dermatology (2025)

Mechanisms Linking Belly Fat To Skin Health

Abdominal or visceral fat is metabolically active and releases inflammatory cytokines that disrupt immune balance and weaken the skin barrier [2].

This process can:

  • Disturb immune regulation, leading to flare-ups
  • Reduce skin resilience, causing irritation and dryness
  • Amplify chronic inflammation, worsening psoriasis symptoms

Researchers found that women were more affected, likely due to hormonal and metabolic factors influencing fat storage and inflammation [1].

Implications For Skincare & Health

Managing abdominal fat may help reduce psoriasis risk and support healthier skin.

ActionDescription
Balanced DietFocus on anti-inflammatory foods rich in omega-3s, antioxidants, and fibre to reduce visceral fat.
Regular ExerciseInclude cardiovascular and core-strengthening activity to reduce inflammation.
Dermatological CareCombine lifestyle adjustments with treatments such as topical corticosteroids or phototherapy.
Inflammation MonitoringTrack inflammatory markers with healthcare professionals for better management.

Table 2: Holistic approaches reduce inflammation and improve skin resilience

Reducing central fat improves systemic inflammation, lowers psoriasis severity, and supports clearer, calmer skin [4].

Monderma’s Role In Psoriasis Skincare

Monderma provides personalised prescription skincare to support individuals with inflammatory conditions such as psoriasis.
Using ingredients like niacinamide and azelaic acid, formulations help soothe redness, strengthen the barrier, and smooth texture.

Each treatment is created by GPhC-registered professionals and designed to complement medical or lifestyle approaches.
All Monderma formulas are fragrance-free and suitable for sensitive or inflamed skin.

Who Benefits From This Research

This study provides valuable insights for:

  • Women with central obesity at higher psoriasis risk
  • Individuals seeking lifestyle-based prevention strategies
  • Dermatologists and nutritionists designing anti-inflammatory care plans
  • People with a family history of psoriasis or metabolic conditions

Recognising how belly fat drives skin inflammation empowers patients and professionals to take a more holistic approach to psoriasis management.

Future Directions For Psoriasis Management

The link between abdominal fat and psoriasis opens new opportunities for prevention and treatment.

Emerging strategies may include:

  • Weight management programmes targeted for psoriasis patients
  • Skincare focused on reducing inflammation in at-risk individuals
  • Gender-specific interventions addressing fat distribution and hormonal factors

Integrating dermatology, nutrition, and personalised skincare could significantly improve long-term psoriasis outcomes [4].

Actionable Steps For Healthier Skin

  • Measure waist circumference and discuss results with your clinician
  • Maintain a balanced, anti-inflammatory diet rich in fruits, vegetables, and omega-3s
  • Engage in regular physical activity to manage inflammation and weight
  • Use niacinamide or ceramide-based skincare to strengthen the barrier
  • Follow trusted research sources such as ScienceDaily for updates

Sharing this knowledge encourages proactive, informed approaches to managing psoriasis risk.

Conclusion

The 2025 findings from King’s College London confirm that abdominal fat and systemic inflammation significantly contribute to psoriasis risk, particularly in women. By addressing central fat through nutrition, exercise, and professional skincare, individuals can help reduce flare-ups and promote long-term skin health.

Monderma supports this holistic approach with evidence-based, prescription skincare aligned with professional care. Take control of your skin health through a personalised Monderma consultation and share this article to raise awareness about the connection between body composition and skin inflammation.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. ScienceDaily. Abdominal fat linked to increased psoriasis risk, particularly in women. 27 May 2025.
  2. Kolb H, Kempf K. Obese visceral fat tissue inflammation: from protective to detrimental. Int J Mol Sci. 2022;23(1):105.
  3. King’s College London. Study finds central body fat more strongly linked to psoriasis risk. 27 May 2025.
  4. Ramessur R, et al. Investigating the Genetic Basis of the Influence of Adiposity on Psoriasis. J Invest Dermatol. 2025.
Categories
Miscellaneous

Understanding The Benefits Of UV Light On Health

UV light, a form of non-ionising electromagnetic radiation, plays a crucial role in human health. Emitted by the sun and artificial sources such as UV lamps and LEDs, it exists beyond visible light on the electromagnetic spectrum. While excessive exposure can cause harm, controlled use of UV light contributes to physical and mental well-being.

This article explores the science behind UV light, its types, and the key benefits it provides when used responsibly.

Types Of UV Light & Their Effects

TypeWavelength RangeProperties and Effects
UVA320–400 nmLong-wave UV forming about 95% of UV radiation reaching Earth. Penetrates deep into the skin, affecting collagen and contributing to ageing.
UVB290–320 nmMedium-wave UV responsible for vitamin D synthesis and sunburn. Vital for bone and immune health.
UVC<290 nmShort-wave UV absorbed by the ozone layer. Artificially produced for germicidal use in sterilisation.

Table 1: Each UV type has distinct wavelengths and biological effects

UVA affects deeper layers of skin, UVB supports vitamin D production, and UVC is primarily used for sterilisation in controlled environments.

Sources Of UV Light

Sunlight

The main natural source, sunlight contains both UVA and UVB rays that influence mood, vitamin D levels, and skin function. Controlled exposure supports health, but prolonged exposure without protection can cause damage.

Artificial UV Sources

  • UV Ray Light Bulbs: Used in tanning, plant growth, and phototherapy.
  • UV LED Lights: Energy-efficient, eco-friendly, and effective for sterilising air and water.
  • UV Lamps: Emit UVC light for germicidal use in hospitals and laboratories.

Short daily exposure to UVB-rich light supports wellness, but overexposure must be avoided.

Health Benefits Of UV Light

When used safely, UV light supports several essential health and wellness processes.

Vitamin D Production

UVB converts 7-dehydrocholesterol in the skin into vitamin D3, vital for bone, immune, and muscle health. NICE guidance suggests 10–30 minutes of midday sun several times weekly supports vitamin D levels, though this varies by skin tone and season [2]. Deficiency remains common in the UK, especially during winter.

Mood Enhancement & WellBeing

Sunlight exposure increases serotonin, which improves mood and focus. Bright light therapy, which mimics natural UV light, reduces symptoms of Seasonal Affective Disorder in up to 80% of patients [3]. UV exposure also helps regulate circadian rhythm, improving sleep quality.

Libido & Energy

Sunlight boosts testosterone and oestrogen, supporting energy and well-being. Controlled studies, however, show variable results regarding vitamin D supplementation and hormone levels [4].

Skin Therapy

UVB light is widely used in dermatology for psoriasis and vitiligo. Narrowband UVB phototherapy improves psoriasis in up to 70% of patients [5]. It reduces inflammation and restores pigment in vitiligo, aiding repigmentation.

Monderma’s prescription skincare complements phototherapy by addressing acne, rosacea, and pigmentation for balanced results.

Immune System Support

Moderate UV exposure increases antimicrobial peptides in skin cells [6]. These peptides strengthen the skin’s defence against bacteria while vitamin D regulates immune response.

Disinfection & Sterilisation

UVC destroys microbes by damaging their DNA. It is used in hospitals, laboratories, and air purification systems, reducing infection rates and controlling multidrug-resistant organisms [7].

BenefitMechanismEffect
Vitamin D ProductionUVB converts skin precursors into vitamin D3Strengthens bones and immunity
Mood EnhancementUVA and UVB increase serotonin and regulate sleepReduces SAD symptoms and stress
Libido & EnergyUV influences hormone activityImproves vitality and mood
Skin TherapyUVB suppresses inflammation and stimulates pigmentTreats psoriasis and vitiligo
Immune SupportUVB boosts antimicrobial peptidesLowers infection risk
DisinfectionUVC destroys microbial DNASterilises air, surfaces, and water

Table 2: Controlled UV exposure promotes diverse health benefits

Potential Risks Of UV Light

Excessive UV exposure damages the skin and eyes. UVA penetrates deeply, accelerating collagen breakdown and premature ageing. UVB causes sunburn and increases long-term skin cancer risk. UVC, though germicidal, can harm tissue if handled unsafely.

Using UV Light Safely

Limit Exposure

Avoid direct sunlight between 10 a.m. and 4 p.m. and apply SPF 30 or higher daily.

Use Protective Gear

Wear UV-protective sunglasses and cover exposed skin during extended outdoor activity.

Manage Timing

Short, consistent exposure in the morning or afternoon delivers benefits with lower risk.

Professional Supervision

For treatments such as phototherapy, always follow a dermatologist’s guidance to ensure safe dosage and technique.

Safety TipPurpose
Use SPF 30+Prevents UV damage
Wear UV-protective eyewearShields eyes from radiation
Short exposure sessionsBalances benefits and safety
Consult a professionalEnsures correct dosage and care

Table 3: Safe UV habits reduce harm while maintaining benefits

Choosing The Right UV Light Source

PurposeRecommended SourceApplication
Vitamin D SupportNatural sunlightShort, regular exposure
DisinfectionUVC lamps or LEDsHospitals, homes, and laboratories
PhototherapyUVB lampsMedical treatment for skin disorders

Table 4: Each UV source serves specific health and safety needs

Monderma’s Role In Skincare

Monderma complements the benefits of responsible UV exposure with prescription skincare designed for acne, ageing, and pigmentation.

Formulas are individually prepared by GPhC-registered professionals using active ingredients such as tretinoin, azelaic acid, niacinamide, and adapalene to improve texture, tone, and clarity.

Conclusion

UV light, encompassing UVA, UVB, and UVC, plays an important role in health when managed carefully. From vitamin D production and immune support to mood regulation and skin therapy, balanced exposure offers proven benefits. Safe, limited use and proper protection ensure these advantages are achieved without harm.

Explore Monderma’s personalised skincare consultation to complement your healthy light habits and support long-term skin health.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. Bolland MJ, Grey A, Avenell A. Effects of vitamin D supplementation on musculoskeletal health. Lancet Diabetes Endocrinol. 2016.
  2. NICE. Vitamin D: Supplement use in specific population groups. PH56. 2014.
  3. Lam RW et al. Efficacy of bright light treatment for depression. JAMA Psychiatry. 2016.
  4. Lerchbaum E et al. Vitamin D and testosterone in healthy men. J Clin Endocrinol Metab. 2017.
  5. Menter A et al. Guidelines of care for psoriasis phototherapy. JAAD. 2010.
  6. Gläser R et al. UVB radiation induces antimicrobial peptides. J Invest Dermatol. 2009.
  7. Anderson DJ et al. Enhanced terminal room disinfection study. Infect Control Hosp Epidemiol. 2017.
Categories
Ingredients

Retinoid Vs Retinol: Key Differences & Daily Benefits

The terms retinoid and retinol often appear in skincare discussions, especially for acne and signs of ageing. Both derive from vitamin A but differ in strength, conversion, and accessibility. Understanding these differences helps you choose the right option for your goals.

This article explains how retinoids and retinol work, compares their results, and helps you identify which is best for your skin type.

What Are Retinoids & Retinols

Retinoids: The Umbrella Term

Retinoids include all vitamin A derivatives that promote skin renewal and collagen production. They are effective for acne, fine lines, and pigmentation by accelerating cell turnover and unclogging pores [1,6].

NHS and NICE guidelines support prescription retinoids such as tretinoin for acne treatment, with noticeable lesion reduction after around 12 weeks [2,5]. Due to their potency, dryness or irritation can occur, so professional supervision is recommended.

Retinol: A Gentle Introduction

Retinol is a milder, over-the-counter form of vitamin A suitable for sensitive or dry skin. It gradually improves tone and texture by converting into retinoic acid within the skin, which activates more slowly but with less irritation.

Studies show consistent retinol use thickens the epidermis and brightens the complexion, improving clarity and resilience over time [3]. It is ideal for first-time users or those seeking steady, visible results.

Key Differences: Retinol Vs Retinoid

Retinoids and retinol share similar functions but differ in potency, activation, and how quickly results appear.

FeatureRetinoidRetinol
Strength & EffectivenessHighly potent; faster results; higher irritation riskMilder; slower results; lower irritation risk
AvailabilityPrescription only; requires clinical oversightOver-the-counter; widely accessible
Conversion ProcessDirectly active; no conversion neededConverts to retinoic acid before acting
Ideal ForAcne, photoaging, pigmentationBeginners, sensitive skin, mild ageing

Table 1: Retinoids act faster, while retinol offers gentler long-term improvements

Strength & Effectiveness

Prescription retinoids work faster because they act directly on the skin. A JAMA study found tretinoin visibly reduces fine lines and pigmentation within 3 to 6 months [4]. Retinol produces similar benefits more gradually with less irritation.

Conversion Process

Retinol converts into retinoic acid through two metabolic steps, lowering potency but improving tolerance [6]. This makes it suitable for gradual adaptation without overwhelming the skin barrier.

Granactive Retinoid Vs Retinol

Granactive Retinoid is a newer, stabilised retinoid complex designed to bridge the gap between strength and gentleness. It provides similar results to retinol with reduced risk of irritation. Clinical evidence suggests improved texture, tone, and comfort [7].

TypeEffectivenessToleranceNotes
RetinoidFast-acting, high potencyModerate irritationPrescription strength for acne or ageing
RetinolModerate effectivenessExcellent toleranceBest for first-time users
Granactive RetinoidBalanced resultsLow irritationPromising option for sensitive skin

Table 2: Granactive retinoid balances clinical efficacy and skin comfort

Choosing Skincare Products For Your Needs

The right vitamin A derivative depends on your goals, skin type, and tolerance.

  • For acne or pigmentation: Prescription retinoids such as tretinoin are most effective under supervision.
  • For sensitive or dry skin: Retinol or granactive retinoid are ideal starting points.
  • For preventative ageing: Mild, over-the-counter retinol supports long-term renewal.

How To Use Retinoids & Retinols

Proper application helps maximise benefits and minimise irritation.

  • Start slowly, applying once or twice weekly, increasing as tolerated
  • Use at night only, as retinoids increase UV sensitivity
  • Hydrate daily with a nourishing moisturiser
  • Always apply broad-spectrum SPF in the morning
StepPurpose
CleanseRemoves oil and dirt before application
Apply Retinoid/RetinolUse a pea-sized amount at night
MoisturiseHydrates and reduces dryness
Sunscreen (AM)Protects from UV-induced sensitivity

Table 3: Consistent skincare routine improves tolerance and effectiveness

Potential Side Effects

Mild irritation, redness, or peeling may occur during early use [6]. These symptoms usually resolve as the skin adapts.

Side EffectFrequencyManagement Tip
Redness or PeelingCommonReduce frequency, use moisturiser
DrynessCommonApply hydrating serum or barrier cream
SensitivityOccasionalUse sunscreen and avoid exfoliants

Table 4: Most side effects are temporary and manageable with proper care

Consult a prescriber if irritation persists. Retinoids are not recommended during pregnancy or breastfeeding.

Monderma’s Personalised Retinoid Skincare

Monderma provides prescription-strength skincare tailored to individual skin needs, using evidence-based ingredients such as tretinoin, adapalene, azelaic acid, and niacinamide.

These formulas are designed to target acne, fine lines, and pigmentation under the care of GPhC-registered professionals. Each treatment is adjusted for safety and efficacy, ensuring balanced, long-term results.

Conclusion

The main difference between retinoids and retinol lies in potency, speed, and tolerance. Retinoids deliver faster, prescription-level results for acne and ageing, while retinol offers a milder approach ideal for sensitive or beginner skin. Both play important roles in skin renewal and long-term radiance. Professional advice ensures the right balance between efficacy and comfort.

Explore your ideal vitamin A treatment through a free online Monderma consultation and discover how tailored prescription skincare can help you achieve clearer, brighter, and smoother skin.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. Kligman, A. M., Grove, G. L., Hirose, R., & Leyden, J. J. Topical tretinoin for photoaged skin. J Am Acad Dermatol. 1986.
  2. NHS. Acne – Treatment.
  3. Kang, S., et al. Application of retinol to human skin in vivo. J Invest Dermatol. 1995.
  4. Weiss, J. S., et al. Topical tretinoin improves photoaged skin. JAMA. 1988.
  5. NICE. Acne vulgaris: Management. NG198. 2021.
  6. Mukherjee, S., et al. Retinoids in the treatment of skin aging. Clin Interv Aging. 2006.
  7. The Ordinary. Granactive Retinoid 2% Emulsion.
Categories
Miscellaneous

Body Modification Around The World: Lip Plates & More

Beauty appears in many forms around the world, shaped by culture, history, and values. Body modification, a deeply rooted global practice, reveals how societies express identity and beauty through physical form.

This article explores the symbolism and meaning behind global body modification and how it shapes beauty standards. It also connects traditional practices to modern self-expression, including how Monderma’s personalised skincare empowers individual confidence.

The Hourglass Figure & Corset Tops

In Western culture, the hourglass figure remains a timeless symbol of beauty. Corset tops, once restrictive garments, have evolved into icons of empowerment and style [1,2].

The History Of Corsetry

Originating in the 16th century, corsets were first used to support posture and shape the torso. By the Victorian era, they had become fashionable symbols of elegance and social standing [1,2].

Women often tight-laced to achieve dramatic silhouettes, reflecting how beauty ideals can drive self-expression through physical modification.

Modern Revival Of Corsets

Contemporary designers have reimagined corsets as empowering fashion statements. Today’s versions blend comfort with structure, celebrating body diversity while nodding to historical ideals [3].

Global Views On The Hourglass Figure

Across cultures, curves have long symbolised vitality and beauty. Ancient Greek statues like Venus de Milo represented rounded femininity, while African cultures often associate fuller figures with health and prosperity. The hourglass ideal continues to bridge tradition and modernity.

Africa: Scarification & The Bodi Tribe

Scarification among the Bodi tribe in Ethiopia remains an art form symbolising beauty, maturity, and belonging [4,5].

Meaning Of Scarification

The Bodi create raised skin patterns to mark personal milestones and social identity. Each design tells a story of strength, unity, and cultural pride [5].

PracticeCultural Purpose
ScarificationSymbol of strength, identity, and belonging
Otjize (Himba)Sunscreen and beauty enhancer
Rites of PassageMark maturity and community connection

Table 1: African practices intertwine function, beauty, and cultural pride

The Himba & Otjize

In northern Namibia, Himba women use otjize, a red ochre and butterfat paste, as skincare and sun protection [6,7]. Its vivid colour represents fertility and resilience. Scientific studies confirm its UV-blocking properties, combining aesthetics with functionality [6].

Evolution Of African Body Art

Although globalisation influences younger generations, many continue to uphold scarification and otjize use as cultural anchors, balancing heritage with modern self-expression [5].

Asia: Skin Whitening & Dental Modifications

Asian beauty ideals often merge ancient and contemporary influences. Skin whitening remains prominent, symbolising refinement and social status, while Japan’s yaeba trend celebrates imperfection [8,9,10].

Japan’s Yaeba Trend

Yaeba, meaning “double tooth,” celebrates natural asymmetry as youthful and charming. Cosmetic dentists in Japan even offer yaeba enhancements that intentionally create slightly uneven teeth [9,10].

Cultural Meaning Of Yaeba

While Western ideals prize alignment, yaeba highlights authenticity and individuality. It aligns with kawaii culture, valuing approachability over perfection [10].

AspectWestern IdealJapanese Ideal
Dental AestheticsStraight and flawlessCrooked and natural
SymbolismMaturity and controlYouthfulness and charm
Common ProceduresWhitening, alignmentYaeba inlays

Table 2: Cultural contrasts reveal beauty as subjective and fluid

Central Asia: The Pamiri People & The Monobrow

Among the Pamiri people, the monobrow symbolises intelligence, wisdom, and inner strength [11].

Symbolism In Pamiri Culture

The monobrow appears in folklore as a mark of intellect and beauty. Studies show 80% of Pamiri women consider it integral to identity [11].

Modern Adaptation

Younger Pamiris combine tradition with modern trends, preserving the monobrow’s meaning while exploring new aesthetics. The global embrace of bold brows reflects this cultural continuity.

South America: Lip Plates & Nose Plugs

In parts of South America and East Africa, lip plates and nose plugs remain striking markers of identity and beauty expression.

Lip Plates Among The Mursi

Mursi women in Ethiopia gradually insert lip plates from adolescence, symbolising social maturity and readiness for marriage [12]. Larger plates often represent higher social status.

Nose Plugs In Amazonian Tribes

Among Amazonian tribes, nose plugs made of bone or wood mark rites of passage and adult transition [12].

PracticeRegionCultural Meaning
Lip PlatesEthiopiaSocial status and identity
Nose PlugsAmazon BasinMaturity and readiness
Decorative PiercingSouth AmericaBeauty and belonging

Table 3: Indigenous modifications highlight identity and transformation

The Pacific: Ta Moko & Māori Tattoo Traditions

In Māori culture, ta moko represents ancestry, courage, and social standing [13,14,15]. Each design tells a personal story of lineage and purpose.

The Art Of Ta Moko

Māori tattoo artists work collaboratively to ensure authenticity and respect. Unlike standard tattoos, ta moko designs are carved into the skin, symbolising depth and permanence [13,15].

Cultural Identity & Revitalisation

Ta moko connects Māori people to their ancestors and heritage. Many young Māori are reviving the tradition as a form of cultural pride and resistance against Western homogenisation [14,15].

ElementMeaning
Facial Ta MokoHeritage and life milestones
Body DesignsFamily lineage and courage
Modern AdaptationPride and reclamation of identity

Table 4: Māori tattoos blend art, memory, and ancestry

Monderma: Personalised Skincare & Modern Beauty

Global beauty traditions celebrate diversity and individuality. Monderma continues this ethos through personalised prescription skincare, created by GPhC-registered professionals.

Each treatment is designed to support skin health and confidence, using clinically proven ingredients such as tretinoin, azelaic acid, niacinamide, and clindamycin. Whether addressing acne, pigmentation, or ageing, every plan is created after clinical review and adjusted for long-term skin wellness.

Western Beauty Standards & Globalisation

Western ideals such as slim figures and clear skin often shape global perceptions through media influence [16]. Yet, traditional aesthetics continue to re-emerge as communities reclaim identity through heritage and artistry.

Resistance & Cultural Reclamation

Indigenous groups are reintroducing scarification, ta moko, and natural adornments to honour their roots [14,16]. These revivals celebrate cultural resilience alongside aesthetic value.

Media Representation & Inclusivity

Modern fashion and beauty campaigns increasingly showcase diverse representations, from Māori tattoos to African scarification [11,12]. This shift promotes appreciation over appropriation and fosters inclusivity in global beauty narratives.

Conclusion

Body modification reflects creativity, heritage, and individuality. From yaeba in Japan to scarification in Ethiopia, these practices celebrate the many faces of beauty worldwide. By understanding and respecting cultural traditions, we can foster appreciation and inclusivity while embracing our unique expressions.

Monderma supports individuality through evidence-based, personalised skincare. Begin your personalised consultation with Monderma’s clinical team and celebrate your beauty story with confidence.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. Steele, V. The Corset: A Cultural History. Yale University Press, 2001.
  2. Kunzle, D. Fashion & Fetishism. The History Press, 2004.
  3. Vogue. “How Fashion Reclaimed the Corset.” 2022.
  4. Pitt Rivers Museum. Scarification. University of Oxford.
  5. TalkAfricana. The Suri People & Scarification.
  6. Havenga, D. et al. Fe₂O₃ UV-Blocking Nanocosmetics. Scientific Reports. 2022.
  7. Gashee Wellness Blog. Red Ochre as Sunblock. 2025.
  8. Japan Dental Association. Trends in Cosmetic Dentistry. 2023.
  9. Kowner, R. Body Dissatisfaction in Japan. Psychology Monographs. 2004.
  10. BBC. “Yaeba Dentistry: The Appeal of Pointy Teeth.” 2018.
  11. Minority Rights Group International. Pamiris. 2025.
  12. Turton, D. Lip-Plates & Tourism in Southern Ethiopia. Anthropology Today. 2004.
  13. Te Awekotuku, N. Mau Moko: The World of Māori Tattoo. Penguin, 2007.
  14. Nikora, L. W., Rua, M., Te Awekotuku, N. Moko in Contemporary New Zealand. J Community & Applied Social Psychology. 2007.
  15. Te Ara. Ta Moko – Māori Tattooing. 2021.
  16. Dittmar, H. Consumer Culture, Identity & Well-Being. Psychology Press, 2007.
Categories
Ingredients

Topical Clindamycin For Acne Explained

Clindamycin is an antibiotic used for bacterial infections including acne.

This guide explains what it is, how it works, who it suits, how to use it safely, and when to seek professional advice.

What Is Clindamycin

Clindamycin is a lincosamide antibiotic that targets anaerobic bacteria. It treats skin, respiratory, dental, and bone infections, especially when penicillin is unsuitable. In skincare, topical clindamycin targets Cutibacterium acnes to reduce inflammation and support clearer skin [1,3].

Historical Background

Clindamycin was derived from lincomycin in 1966 and became a valuable option for resistant infections. By the 1970s it entered dermatology as a topical acne treatment. Ongoing use reflects consistent clinical utility [1].

How Clindamycin Works

Clindamycin binds to bacterial ribosomes to block protein synthesis. This prevents bacterial growth and allows the immune system to clear infection more efficiently. Its tissue penetration supports treatment of both surface and deeper infections [2].

Supporting The Immune System

By lowering bacterial load, clindamycin helps reduce inflammation and immune strain. This dual action benefits difficult infections such as osteomyelitis when clinically indicated [6].

Common Uses Of Clindamycin

Clindamycin may be prescribed for cellulitis, pneumonia, bone infections, and dental abscesses. In dermatology, topical clindamycin is used for acne where it targets C. acnes and helps calm inflamed lesions [1,3,6].

Clindamycin & Acne Treatment

Topical clindamycin reduces C. acnes and visible inflammation. Combination with benzoyl peroxide is commonly recommended to enhance antibacterial action and lower resistance risk. Studies show meaningful lesion reduction after 12 weeks of consistent use [3,7].

A double blind trial found topical clindamycin comparable to oral minocycline for improving acne severity with a favourable safety profile [4]. A prescriber can advise on suitability based on your skin and medical history.

Other Dermatological Uses

Topical clindamycin may help folliculitis and boils by reducing bacterial growth and swelling. Evidence for rosacea remains limited and is not conclusive at this time [6].

Key Benefits Of Clindamycin

BenefitDescription
Broad spectrumTargets a range of relevant bacteria
Deep tissue reachPenetrates skin, joints, and bone tissues
Resistance backupOption when other antibiotics are unsuitable
Acne reductionLowers bacteria and inflammation in acne

Table 1: Summary of antibacterial coverage and acne related benefits

Using Clindamycin Safely

Correct use supports results and helps limit resistance development [9]. Formulation and route depend on indication. Oral capsules are used for systemic infections. Topical formulations are used for acne.

Intravenous use is reserved for severe infections in clinical settings [9]. For oral forms, swallow with a full glass of water to reduce throat irritation and complete the full prescribed course. Store as directed on the label [10].

Practical Tips

  • Cleanse and dry skin before applying topical clindamycin
  • Apply a thin layer to affected areas twice daily unless advised otherwise
  • Expect results within 6 to 12 weeks with consistent use [3,7]
  • Pair with benzoyl peroxide when recommended to reduce resistance risk
  • Avoid other topical antibiotics unless your prescriber agrees
  • Use non comedogenic moisturiser and daily sunscreen to support skin barrier

Clindamycin Side Effects

Most people tolerate clindamycin. Possible effects include mild nausea or diarrhoea. Topical use may cause temporary redness or dryness. A rare but serious risk is Clostridioides difficile associated diarrhoea, mainly with oral use.

Seek medical help for severe, persistent, or bloody diarrhoea, abdominal pain, or signs of dehydration [11,13].

Side effectFrequencyManagement tip
Nausea or diarrhoeaAround 10 percentTake with food if suitable
C. difficile infectionAround 1 to 2 percentUrgent care if diarrhoea persists
Skin irritationLess than 0.1 percentStop use and seek advice if rash develops

Table 2: Common reactions and when to seek help

Alternatives & Precautions

If allergy or adverse effects occur, alternatives may include doxycycline or metronidazole depending on the condition and clinical judgement [14]. People with gastrointestinal disease or liver issues should use clindamycin with medical supervision.

Share all medicines with your prescriber since interactions can occur, including with neuromuscular blockers [11]. Topical therapy generally carries lower systemic risk than oral therapy but still requires monitoring.

Long Term Use Insights

Extended antibiotic use may increase resistance risk and alter gut flora [5,13]. Overuse of topical clindamycin can promote resistant C. acnes strains [13]. Regular reviews, time limited courses, and combination strategies such as adding benzoyl peroxide can help maintain effectiveness.

Does Clindamycin Really Work

Evidence and clinical experience show clindamycin can be effective for acne and bacterial infections when used correctly. Outcomes depend on adherence, correct formulation, duration, and professional oversight. No treatment suits everyone. Your clinician will guide personalised choices.

Monderma’s Personalised Skincare Approach

Monderma offers prescription skincare for acne. Formulas may include clindamycin, tretinoin, or adapalene where clinically appropriate. A GPhC registered professional reviews your health information and may design a personalised plan to balance efficacy with safety.

Conclusion

Clindamycin is a well-established antibiotic that helps treat acne and other bacterial infections by limiting bacterial growth and calming inflammation.

For safe, effective use, explore Monderma’s free consultation to receive support on possible formulas and direction.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. American Chemical Society. Clindamycin. 2022.
  2. Spížek J, Řezanka T. Lincosamides: Mechanism of Action & Applications. Biochem Pharmacol. 2017.
  3. Gold MH et al. Clindamycin Phosphate 1.2% & Benzoyl Peroxide 2.5% Review. J Clin Aesthet Dermatol. 2012.
  4. Sheehan-Dare RA, et al. Topical Clindamycin vs Oral Minocycline in Acne. Acta Derm Venereol. 1990.
  5. Simpson NB. Antibiotics in Acne: Time for a Rethink. Br J Dermatol. 2001.
  6. Brown NM et al. Treatment of MRSA Infections. JAC-AMR. 2021.
  7. MedlinePlus. Clindamycin. Updated 2024.
  8. Drugs.com. Clindamycin Patient Tips. 2023.
  9. WebMD. Clindamycin (Cleocin) Overview. 2024.
  10. AJMC. C. difficile Risk with Clindamycin & Antibiotics. 2023.
  11. DrugBank Online. Clindamycin Interactions. 2021.
  12. European Lessons on Antibiotic-Resistant Acne. Br J Dermatol. 2003.
  13. Frontiers in Microbiology. Antibiotic Resistance in Cutibacterium acnes. 2025.
  14. Murphy PB, Bistas KG, Patel P. Clindamycin. StatPearls. 2024.
Categories
Treatments

Atrophic Scars Treatments & Remedies

Atrophic scars, such as ice pick, boxcar, and rolling scars, are common concerns that affect confidence and skin texture. Recognising their causes and available treatments helps individuals achieve smoother, healthier skin.

This article explains atrophic scars, distinguishes them from acne marks, and explores effective ways to treat and prevent them using both clinical and at-home skincare approaches.

What Are Atrophic Scars?

Atrophic scars appear as indentations in the skin where tissue loss has occurred due to insufficient collagen during healing. They form after acne, surgery, or injury when the body cannot regenerate enough dermal tissue [1,2].

Unlike hypertrophic scars, which rise above the skin, atrophic scars sit below the surface, creating a shadowed appearance that can worsen with certain lighting.

Acne Marks Vs. Acne Scars

Atrophic scars differ from acne marks, also known as post-inflammatory hyperpigmentation. Acne marks are flat and discoloured but usually fade naturally over time. Scars, however, cause permanent texture changes that require active treatment.

Identifying the difference ensures the right approach, using topical brighteners for pigmentation versus structural treatments for scarring.

Types Of Atrophic Scars

Each scar type presents differently and may need distinct treatment methods:

Ice Pick Scars

Narrow and deep, these scars resemble small punctures in the skin. They often form after severe cystic acne and are among the hardest to treat.

Boxcar Scars

Broader and rectangular, boxcar scars have sharp edges and may be shallow or deep depending on collagen loss. Treatment effectiveness varies by depth.

Rolling Scars

Wavy, undulating scars result from damage below the surface and fibrous tissue pulling the skin inward. Subcision is especially effective for this type [3].

Causes Of Atrophic Scars

Atrophic scars form when inflammation or trauma disrupts collagen production. Key causes include:

  • Acne Vulgaris: Chronic or cystic acne degrades collagen and damages tissue.
  • Injury or Surgery: Improper healing from deeper wounds can lead to indentations.
  • Chickenpox: Healed lesions may leave residual pitted scars.

Prompt acne management and proper wound care significantly reduce scarring risk.

Atrophic Scar Treatment Options

Treating atrophic scars often involves combining therapies to stimulate collagen, smooth texture, and improve tone.

Topical Treatments

Retinoid-based creams containing tretinoin or adapalene boost collagen and accelerate cell turnover. Over time, they help smooth fine depressions [7,8]. Monderma offers prescription retinoid formulations tailored to individual needs after a free online consultation.

Chemical Peels

Procedures such as CROSS (Chemical Reconstruction of Skin Scars) remove damaged surface layers and encourage new collagen growth. A 2002 study found medium-depth peels significantly improved atrophic scars in darker skin tones [4].

Microneedling

This minimally invasive treatment uses fine needles to trigger collagen production. Studies show microneedling, especially when combined with platelet-rich plasma (PRP), improves scar depth and texture [5].

Laser Therapy

Fractional CO₂ laser resurfacing promotes collagen synthesis and smooths the skin. A 2012 randomised trial confirmed marked improvement in atrophic acne scars using fractional CO₂ treatment [6].

Dermal Fillers

Injectable fillers like hyaluronic acid lift indented scars temporarily, especially boxcar and rolling types. Results are immediate but require maintenance over time.

Punch Techniques

Severe or deep scars may require surgical excision or punch grafting. These techniques replace or lift scar tissue for long-lasting correction under clinical supervision.

Summary Of Atrophic Scar Treatments

TreatmentSummary
Topical TreatmentsRetinoids and vitamins stimulate collagen and renew skin.
Chemical PeelsExfoliate surface layers and smooth uneven texture.
MicroneedlingStimulates collagen with minimal downtime.
Laser TherapyResurfaces skin and refines scar depth.
Dermal FillersTemporarily raise sunken scars for smoother skin.
Punch TechniquesSurgically remove or replace deep scars.

Table 1: Overview of treatment options for atrophic acne scars

Preventing Atrophic Scars

Preventing scars begins with early acne management and healthy healing habits.

  • Treat Acne Early: Use prescription treatments promptly to avoid tissue damage.
  • Avoid Picking or Squeezing: Reduces inflammation and prevents deep lesions.
  • Follow Post-Surgery Care: Proper wound management aids collagen repair.

Balanced nutrition and hydration also support the body’s natural healing process [12].

Monderma’s Personalised Approach To Atrophic Scars

Monderma’s prescription skincare combines evidence-based ingredients to target scarring and pigmentation. Each formula is crafted by GPhC-registered prescribers following a free online consultation.

Preventing Scars With Early Acne Treatment

Monderma’s acne solutions, including adapalene, tretinoin, and clindamycin, reduce inflammation and bacterial growth to prevent new scars from forming.

Skincare For Mild Scars

For early or shallow atrophic scars, tretinoin or adapalene can rebuild collagen and refine texture within 12 weeks of consistent use.

Complementing In-Clinic Treatments

When used alongside professional procedures like microneedling or laser therapy, Monderma’s formulas support collagen repair and reduce post-procedure irritation with niacinamide and azelaic acid [9,10,11].

Managing Hyperpigmentation With Atrophic Scars

Hydroquinone-based Monderma blends target dark marks accompanying scarring. Combined care improves both colour and texture for a balanced complexion [9].

Affordable, Accessible Prescription Skincare

Monderma provides high-strength, prescription-only ingredients without private clinic costs. Free consultations and UK-wide delivery make advanced skincare accessible to those over 16.

Ongoing Care & Progress Tracking

Monderma’s ongoing care adjusts formulas as skin improves, ensuring long-term maintenance and continuous progress in scar reduction.

Monderma Ingredients That Help With Atrophic Scarring

IngredientWhat It IsHow It Helps Atrophic Scarring
TretinoinA vitamin A derivative that promotes cell turnover.Stimulates collagen to smooth and reduce scar depth [7,8].
AdapaleneSynthetic retinoid that regulates cell renewal.Boosts collagen to improve skin texture [7].
Azelaic AcidAnti-inflammatory exfoliating acid.Smooths surface and fades hyperpigmentation [10].
NiacinamideVitamin B3 compound supporting barrier function.Enhances skin repair and evens tone [9].
HydroquinoneSkin-lightening ingredient.Reduces pigmentation accompanying atrophic scars [9].
ClindamycinTopical antibiotic.Prevents acne bacteria and new scar formation [11].

Table 2: Monderma ingredients that support atrophic scar improvement

Conclusion

Atrophic scars can be effectively treated with the right combination of medical treatments and personalised skincare. From retinoids and lasers to targeted formulas, patients have more options than ever to restore smoother, more even skin.

Monderma’s expert-prescribed skincare offers tailored solutions for atrophic scars, acne, and hyperpigmentation. Begin your personalised journey today with a free online consultation, and share this article to help others learn how to improve scarred skin with confidence.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. Goutos I. Atrophic Scars. Goutos London, 2024.
  2. Moon J, Yoon JY, Yang JH, et al. Atrophic Acne Scar: A Process from Altered Metabolism of Elastic Fibres and Collagen Fibres. Br J Dermatol. 2019.
  3. Alam M, Omura N, Kaminer MS. Subcision for Acne Scarring: Technique & Outcomes. Dermatol Surg. 2005.
  4. Al-Waiz M, Al-Sharqi A. Medium-Depth Chemical Peels in Acne Scars. Dermatol Surg. 2002.
  5. Ismail SA, Khella NAH, Abou-Taleb DAE. Microneedling vs PRP for Atrophic Scars. Dermatol Ther. 2022.
  6. Hedelund L, et al. Fractional CO₂ Laser Resurfacing for Atrophic Acne Scars. Lasers Surg Med. 2012.
  7. Medical-Aesthetics.sg. Retinoids & Acne: How Vitamin A Fights Scarring. 2024.
  8. Brickell Men’s Products. Retinol for Acne Scars. 2024.
  9. Navarrete-Solís J, et al. Niacinamide vs Hydroquinone in Melasma. Dermatol Res Pract. 2011.
  10. Marques C, et al. Mechanistic Insights into Niacinamide Functions. Antioxidants (Basel). 2024.
  11. Zaenglein AL, Pathy AL, Schlosser BJ, et al. Guidelines for Acne Management. J Am Acad Dermatol. 2016.
  12. Roengritthidet K, et al. Diet & Acne Severity Study. Acta Derm Venereol. 2021.
Categories
Miscellaneous

AI In Healthcare: Precision & Personalisation

Artificial intelligence (AI) is reshaping skincare by delivering precise, personalised solutions tailored to individual skin needs. Through AI skin analysis and innovative technology, dermatologists now have advanced methods to diagnose and treat skin conditions effectively.

In this article, we explore how the integration of AI in healthcare enhances accessibility and confidence, helping individuals manage skin health with greater ease.

AI-Powered Skin Analysis: Understanding Your Skin

AI skin analysis allows users to assess their skin remotely. By processing images with advanced algorithms, AI systems detect concerns such as acne, fine lines, or hyperpigmentation, recommending suitable treatments.

A study in Nature Medicine reported AI-based dermatology assessments achieved diagnostic accuracy comparable to dermatologists, reaching 66% accuracy versus 63% for experts [1]. These systems recognise subtle patterns, such as early pigmentation changes, often missed by the human eye, offering a foundation for informed skincare decisions.

As AI databases expand, diagnostic precision continues improving, helping clinicians align treatments with unique skin profiles for better outcomes.

Online Skin Consultations: Accessible Expertise

AI-powered online consultations enable professional skincare guidance from home. Platforms analyse skin images using extensive datasets, generating targeted recommendations. A PubMed review found that AI-supported teledermatology significantly improved patient satisfaction due to accessibility and shorter wait times [2].

This accessibility benefits busy individuals or those in remote regions, ensuring timely management for concerns such as acne or rosacea. AI for healthcare diagnosis supports dermatologists in prioritising cases efficiently, optimising both patient care and system resources.

Skincare Product Innovation: Precision Formulations

AI technology contributes to targeted skincare product development, refining formulations for conditions like acne, ageing skin, or hyperpigmentation. By analysing clinical data and user feedback, AI aids ingredient selection and dosage optimisation.

Tretinoin, a retinoid, boosts skin cell turnover, reducing acne lesions when used consistently [3]. Azelaic acid reduces inflammation and hyperpigmentation, improving skin tone [4].

Monderma uses AI-supported formulation design to develop prescription skincare that is effective, safe, and evidence-based.

Benefits Of AI In Skincare: Efficiency & Effectiveness

AI integration in skincare brings several advantages, improving outcomes and convenience.

Personalised Skincare

AI skin analysis evaluates thousands of variables to create tailored skincare plans. NICE guidelines on acne management note that personalised topical treatments, such as those with adapalene, improve adherence and efficacy [5].

Enhanced Diagnosis

AI supports early detection of skin diseases, enhancing accuracy. A study found AI tools identify melanoma with accuracy comparable to dermatologists [6]. These insights assist early intervention for pigmentation or other chronic issues.

Time & Cost Efficiency

Teledermatology with AI reduces the need for frequent in-person visits, saving time and costs. Studies show significant reductions in consultation expenses compared with traditional care [7].

Monderma’s digital-first model streamlines this approach, offering affordable, clinically guided skincare prescriptions.

BenefitDescription
Personalised SkincareAI creates regimens tailored to individual skin needs.
Enhanced DiagnosisAI detects early skin conditions with precision.
Time & Cost EfficiencyReduces visits, saving time and money.

Table 1: Summary of AI benefits in personalised skincare

Monderma: Personalised Prescription Skincare

Monderma provides prescription skincare for acne, rosacea, hyperpigmentation, and ageing skin, developed by GPhC-registered professionals. Formulations may include active ingredients such as adapalene, azelaic acid, and tretinoin, each tailored to the user’s skin type and goals.

Through AI-informed assessment and clinical review, Monderma ensures precision and safety. Individuals can begin their journey with a free online consultation.

Future Innovations: The Next Frontier

Emerging AI technology continues to expand skincare possibilities, with upcoming innovations focusing on real-time insights and predictive analytics.

Smart Skincare Devices

Next-generation skincare devices will use AI to analyse skin in real time and dispense products precisely. This innovation ensures accurate dosing and consistent application, enhancing product performance and compliance.

Virtual Skincare Assistants

AI-driven virtual assistants will soon guide users through skincare routines, offering real-time advice and adjustments. These assistants support better self-management and education for users at home.

Health Data Integration

Future systems will merge skincare data with broader health metrics such as diet, stress, or environment. Integrating AI in healthcare diagnostics across disciplines, including dermatology, mirrors its success in other medical fields like radiology [8].

Challenges & Considerations: Responsible Implementation

Although AI in healthcare offers major advantages, it requires careful ethical and technical oversight.

Data Privacy

Patient confidentiality must remain central. The NHS mandates encryption and transparent data use to sustain trust in digital health platforms [9]. Monderma follows these principles to ensure data security during online consultations.

Accuracy & Bias

AI systems must rely on diverse datasets to avoid biased outputs. A JAMA study stressed the need for inclusivity in algorithm training to ensure fairness across all skin tones [10].

Human Expertise

AI complements, rather than replaces, clinical judgment. According to NICE rosacea management guidance, dermatologist input remains essential for complex or evolving conditions [11].

ChallengeDescription
Data PrivacyProtecting patient data maintains trust in AI systems.
Accuracy & BiasDiverse datasets prevent biased skincare recommendations.
Human ExpertiseAI supports but cannot replace dermatologists.

Table 2: Challenges and considerations in integrating AI with clinical skincare

Embracing AI For Enhanced Skin Health

AI in healthcare represents a major shift toward precision and accessibility in skincare. By combining AI skin analysis with expert-prescribed treatments, individuals can achieve healthier, clearer skin with confidence.

Platforms like Monderma exemplify this integration, merging technology with human expertise for optimal results. Complete a free consultation to discover your personalised skincare solution and share this article to help others understand how AI is transforming skincare.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. Liu Y, Jain A, Eng C, et al. A Deep Learning System for Differential Diagnosis of Skin Diseases. Nature Medicine, 26(6), 900–908.
  2. Lee JJ, English JC. Teledermatology: A Review and Update. Am J Clin Dermatol, 19(2), 253–260.
  3. StatPearls. Tretinoin. StatPearls Publishing, 2023.
  4. StatPearls. Acne Vulgaris. StatPearls Publishing, 2023.
  5. NICE. Acne Vulgaris: Management. NG198.
  6. Esteva A, Kuprel B, Novoa RA, et al. Dermatologist-Level Classification of Skin Cancer with Deep Neural Networks. Nature, 542(7639), 115–118.
  7. Snoswell CL, Taylor ML, Caffery LJ. The Cost-Effectiveness of Teledermatology. J Telemed Telecare, 26(7–8), 423–431.
  8. Topol EJ. High-Performance Medicine: The Convergence of Human & Artificial Intelligence. Nature Medicine, 25(1), 44–56.
  9. NHS Digital. Data Security & Protection Toolkit. NHS, 2023.
  10. Adamson AS, Smith A. Machine Learning & Health Care Disparities in Dermatology. JAMA Dermatology, 154(11), 1247–1249.
  11. NICE Clinical Knowledge Summaries. Rosacea | Management (NICE CKS).
Categories
Ingredients

The Beginners Guide To Using Tazarotene Safely

Tazarotene is a potent topical retinoid, effective for psoriasis but currently unavailable in the UK. It normalises skin cell turnover and reduces inflammation for acne and photoageing. Tazarotene may cause more irritation than tretinoin but can offer stronger results.

In this guide, we outline proper use, including gentle cleansing, moisturising, sun protection, and gradual application, as well as important precautions such as avoiding use during pregnancy and not combining it with harsh skincare products.

Understanding Tazarotene

Tazarotene is a synthetic vitamin A derivative used to treat psoriasis, acne, and signs of photoageing. Available in cream, gel, and foam formulations, it works by regulating cell turnover and inflammation. Although it was once licensed in the UK for mild to moderate plaque psoriasis, it is not currently available [1].

By influencing gene expression and skin renewal, tazarotene helps reduce abnormal skin growth and inflammation, improving both appearance and comfort for those with chronic dermatological conditions.

Mechanism Of Action

Tazarotene binds to retinoic acid receptors (RARs), regulating genes that control cell proliferation, differentiation, and inflammation. This process helps normalise skin turnover, making it valuable for conditions like psoriasis and acne [2,3].

AspectDetails
Target ReceptorsRetinoic acid receptors (RAR-β, RAR-γ)
Primary ActionsModulates cell growth, reduces inflammation
Effect on Skin CellsNormalises keratinocyte proliferation
Anti-Inflammatory RoleMay reduce cytokines such as IL-6
Clinical RelevanceImproves skin texture, reduces plaques and comedones

Table 1: Mechanism of action and clinical relevance of tazarotene

Clinical Applications

Psoriasis

Tazarotene helps thin plaques, reduce redness, and normalise cell growth. Clinical studies show 0.05%–0.1% gels improve mild to moderate plaque psoriasis [4].
It may irritate surrounding skin, so careful application and moisturisation are essential [2].

Acne Vulgaris

Though not licensed in the UK for acne, tazarotene shows strong efficacy internationally. It reduces comedones and inflammation while helping prevent new breakouts [5,6].

Photoageing

Tazarotene stimulates collagen and smooths photoaged skin. Studies show 0.1% cream performs comparably or better than tretinoin 0.05% in reducing pigmentation and fine lines [7].

IndicationUK Licence StatusMechanism/EffectEvidence/Benefit
PsoriasisPreviously licensed, now unavailableRegulates skin cell growthReduces plaques and scaling
AcneNot licensed in UKNormalises cell turnoverEffective for comedones and inflammation
PhotoageingNot licensedStimulates collagenSmooths texture and reduces wrinkles

Table 2: Indications, mechanisms, and benefits of tazarotene

Tazarotene Vs. Tretinoin

FeatureTazaroteneTretinoin
Retinoid GenerationThirdFirst
PotencyGenerally higherModerate
Receptor SelectivityTargets RAR-β, RAR-γLess selective
Efficacy for AcneHigh, per clinical trialsEstablished
Irritation PotentialHigherModerate
Photoageing UseEffectiveEffective
Benzoyl Peroxide StabilityStableInactivated (unless microsphere)
Pregnancy ContraindicationYesYes
UK LicencePreviously for psoriasisFor acne

Table 3: Comparison of tazarotene and tretinoin characteristics

Usage Guidelines For Tazarotene

Application Steps

  1. Cleanse with a mild, non-irritating cleanser.
  2. Dry skin completely before applying a thin layer of tazarotene.
  3. Moisturise with a non-comedogenic product to minimise dryness.
  4. Use SPF 30+ daily to protect against sun sensitivity.
StepGuidance
CleansingUse gentle cleanser; avoid scrubbing
ApplicationThin layer only on affected skin
MoisturisationApply after treatment to maintain barrier
Sun ProtectionBroad-spectrum SPF during daytime
Starting FrequencyAlternate nights for 2–3 weeks
Increased UseNightly once tolerated
Expected ResultsAround 12 weeks

Table 4: Recommended usage steps and precautions for tazarotene

Considerations & Precautions

FactorRecommendation
PregnancyContraindicated; use effective contraception
LactationConsult healthcare provider before use
Other TopicalsAvoid exfoliants, acids, or strong astringents
Benzoyl PeroxideSafe to combine (unlike tretinoin)
Skin IrritationManage with moisturiser and reduced frequency
PhotosensitivityAlways use SPF 30+

Table 5: Key considerations and safety precautions for tazarotene use

Research & Future Developments

Emerging studies are exploring tazarotene for keratosis pilaris, actinic keratosis, and even certain skin cancers. Formulation advances, such as microsphere gels and foam vehicles, aim to improve tolerability and reduce irritation while maintaining its efficacy [9,10].

Monderma’s Role In Personalised Skincare

Monderma offers bespoke prescription skincare for acne, ageing, and pigmentation. Active ingredients may include:

  • Tretinoin for collagen support and anti-ageing
  • Adapalene for acne management
  • Azelaic acid and hydroquinone for pigmentation
  • Ivermectin for rosacea management

While tazarotene is not currently available in the UK, Monderma intends to offer it as soon as it becomes licensed again. For now, equivalent prescription retinoids like tretinoin are formulated through Monderma’s free consultation service, ensuring safe, evidence-based care tailored to each individual’s skin.

Conclusion

Tazarotene is a potent third-generation retinoid that normalises cell turnover, reduces inflammation, and supports collagen production. Though more irritating than tretinoin, it can be more effective for conditions like psoriasis, acne, and photoageing.

Currently unavailable in the UK, its proven mechanism and versatility make it a vital option once reintroduced. Until then, alternatives such as tretinoin and adapalene offer accessible and effective solutions. To discover a personalised skincare plan, including prescription retinoids suited to your skin, complete your free online consultation.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. Patient.info. Tazarotene for Psoriasis.
  2. NHS Barnsley CCG. Psoriasis Patient Information Sheet. 2018.
  3. Cosmoderma. Exploring Tazarotene’s Role in Dermatology.
  4. Krueger GG, Stingl G, Koo J, et al. Safety and Efficacy of Tazarotene Gel. Arch Dermatol. 1998;134(1):57–60.
  5. NICE CKS. Acne Vulgaris – Topical Retinoids.
  6. Medical News Today. Tazarotene Topical Cream: Uses and Side Effects.
  7. Lowe N, Gormley D, Stoll S, et al. Tazarotene vs Tretinoin in Photodamaged Skin. J Am Acad Dermatol. 2004;50(6):882–890.
  8. Leyden JJ, Tanghetti EA, Miller B, et al. Tazarotene 0.1% vs Tretinoin 0.1% Gel for Acne. Cutis. 2002;69(2 Suppl):12–19.
  9. WebMD. Tazarotene (Tazorac, Arazlo) – Uses & Side Effects.
  10. Psoriasis Association. Tazarotene (Zorac).
  11. Drugs.com. Is Tazarotene Better Than Tretinoin?
Categories
Treatments

Hydroquinone In Melasma Treatment: How It Works

Melasma is a common pigmentation disorder marked by brown or grey patches on the face. While harmless, its visibility often affects confidence and emotional well-being.

In this article, we explore hydroquinone’s role as the gold standard for fading dark patches and restoring an even skin tone, including how it works and safe ways to use it for brighter, clearer skin.

Causes & Triggers Of Melasma

Hormones, Sun & Genetics

Melasma often develops due to hormonal changes, such as pregnancy or contraceptive use. Between 10–50% of pregnant women experience melasma, sometimes called the mask of pregnancy [1]. Genetic predisposition also plays a strong role, especially in individuals with darker skin tones [2,7].

The Role Of Sun Exposure

Ultraviolet (UV) radiation stimulates melanocytes, increasing melanin production and worsening dark patches. Melasma tends to intensify during summer [3].

Using broad-spectrum SPF 30+ sunscreen daily is essential to prevent flare-ups and enhance treatment success [4].

TriggerEffect on SkinManagement Tip
Hormonal changesStimulate melanin productionConsult about hormonal control options
Sun exposureDeepens pigmentationUse SPF 30+ daily
GeneticsIncreases melasma riskUse long-term maintenance care

Table 1: Common melasma triggers and recommended management strategies

Emotional & Psychological Effects

Melasma can significantly affect confidence and quality of life. Over 50% of patients report psychological distress related to their appearance [7,8].
Addressing pigmentation not only improves skin tone but also supports mental well-being and self-assurance.

How Hydroquinone Works

Mechanism of Action

Hydroquinone inhibits tyrosinase, an enzyme essential for melanin synthesis. By reducing pigment production, it gradually lightens dark patches.

Topical strengths between 2% and 4% are widely used, with visible improvement typically seen after 4–8 weeks of consistent application [2,5].

Duration & Effectiveness

Patients often notice early lightening within 2–4 weeks, with significant improvement by 8–12 weeks [2,4,5]. Maintenance therapy, combined with sunscreen, helps preserve results.

StrengthTime to Noticeable ResultsTypical Use
2%6–8 weeksMild pigmentation
4%4–6 weeksModerate to severe melasma

Table 2: Typical hydroquinone strengths and expected treatment results

Using Hydroquinone Safely

Overuse or incorrect application can lead to redness or irritation, especially in sensitive skin types.
To use safely:

  • Apply only to affected areas.
  • Use moisturiser to reduce dryness or stinging.
  • Always apply SPF 30+ daily to prevent rebound pigmentation.
  • Conduct a patch test before full application [3,4].

Monderma’s licensed prescribers provide clear guidance on safe use and concentrations tailored to your skin type via a free consultation.

Why Hydroquinone Is A Leading Option

Proven Results

Clinical evidence supports hydroquinone’s success. A 2013 study found 4% hydroquinone reduced melasma severity in 80% of patients within 12 weeks [5].

Fast-Acting & Accessible

It acts faster than many alternatives, offering visible improvement and confidence boosts within weeks. Monderma enhances these results through custom blends combining hydroquinone with hydrating actives like hyaluronic acid.

Hydroquinone Vs. Other Melasma Treatments

Azelaic Acid

Derived from grains, azelaic acid (20%) reduces melanin and inflammation. A 2023 study showed it effectively improved melasma while causing fewer side effects than hydroquinone [11].
Best for sensitive or reactive skin.

Chemical Peels

Glycolic or lactic acid peels exfoliate surface cells, complementing hydroquinone. Studies show up to 60% improvement in pigmentation when used together under professional guidance [6].

TreatmentMechanismBest For
HydroquinoneInhibits melanin enzymeFast, targeted lightening
Azelaic AcidReduces pigment & inflammationSensitive skin
Chemical PeelsBoosts cell turnoverStubborn pigmentation

Table 3: Comparative treatments for pigmentation and their best uses

Hydroquinone Before & After Timeline

TimelineExpected Results
2–4 WeeksSubtle fading of dark patches
8–12 WeeksNoticeable reduction and even tone
12+ WeeksMaintenance phase with ongoing protection

Table 4: Hydroquinone treatment timeline and expected results

Monderma’s Personalised Skincare Solutions

Monderma offers prescription-strength skincare tailored for melasma, acne, and pigmentation concerns. Custom formulas may include hydroquinone, azelaic acid, and niacinamide, developed by GPhC-registered prescribers for both safe and effective use.

Conclusion

Hydroquinone remains the most effective treatment for melasma, offering rapid, targeted results through melanin inhibition. When paired with consistent sun protection, gentle skincare, and professional oversight, it delivers safe, lasting improvements in skin tone and confidence.

For expert-led, prescription-based care, visit Monderma’s free consultation portal to discover a treatment designed specifically for your skin’s needs.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. Handel AC, Miot LDB, Miot HA. Melasma: A Clinical and Epidemiological Review. An Bras Dermatol. 2014.
  2. Jo JY, Kim JE, Park YW, Lee JH. Update on Melasma Treatments. Ann Dermatol. 2024.
  3. British Skin Foundation. Melasma. 2020.
  4. Albzea W, Algarni AA, Alzubaidi H, et al. Azelaic Acid Versus Hydroquinone for Managing Melasma. Cureus. 2023.
  5. Monteiro RC, Moura HH, Dantas DC, et al. Comparative Study of Hydroquinone and Kojic Acid Cream. J Clin Diagn Res. 2013.
  6. Garg S, Sarkar R, Mysore V, et al. Chemical Peels in Melasma: Consensus Recommendations. J Cutan Aesthet Surg. 2017.
  7. Majid I, Aleem S. Melasma: Update on Epidemiology, Clinical Presentation, and Scoring. J Skin Stem Cell. 2022.
  8. Platsidaki E, Markantoni V, Nicolaidou E, et al. Self-Esteem, Depression, Anxiety and Quality of Life in Melasma Patients. Clin Cosmet Investig Dermatol. 2023.
Categories
Miscellaneous

The Impact Of Psyche On The Skin

The skin, the body’s largest organ, reflects both physical and emotional health. Stress, anxiety, and other psychological factors can intensify visible skin issues, while chronic conditions may, in turn, erode confidence and self-esteem.

This article explores how mental wellbeing and skin health are deeply connected, how stress affects the skin, how skin conditions influence mood, and how a balanced, holistic approach can support both.

The Bidirectional Impact: Skin & Psyche

How Skin Conditions Influence Mental Health

Visible skin concerns like acne, eczema, and psoriasis can significantly affect emotional wellbeing. Research shows that a large proportion of dermatology patients experience depression or anxiety related to their condition [1].

Persistent visibility and stigma may lead to social withdrawal, reduced intimacy, or avoidance of public settings. For instance, ectoparasitic conditions such as scabies can cause feelings of shame and disgust, delaying care [2].

Over time, the emotional burden creates a cycle, in stress worsens skin inflammation, which heightens distress and further aggravates the condition.

Psychological Effects Of Specific Skin Conditions

Skin ConditionPsychological Effects
AcneReduced self-esteem, anxiety, avoidance of social contact
Atopic DermatitisSocial isolation, frustration, dependency in children
PsoriasisShame, helplessness, depression, suicidal thoughts
RosaceaEmbarrassment, anxiety, avoidance of triggers
Ageing SkinDiminished confidence, stress, obsessive behaviours
HyperpigmentationLow self-esteem, cultural distress, social avoidance

Table 1: Overview of the connection between mental wellbeing and skin health

Psychological Factors Shaping Skin Health

Stress & Its Impact on Skin

Stress triggers cortisol release, which increases oil production and inflammation. This can exacerbate acne, eczema, and psoriasis, as well as slow wound healing. Chronic stress also weakens the skin barrier, leading to dryness and sensitivity.

Anxiety & Skin Manifestations

Anxiety often shows up through itching, hives, or hair loss, and may lead to compulsive behaviours like scratching or skin picking [8]. These habits intensify visible irritation, worsening both the skin and psychological state.

Psychological Skin Disorders

Conditions like trichotillomania (hair-pulling) or dermatillomania (skin-picking) stem from anxiety or trauma. Addressing both the emotional cause and dermatological damage through therapy and dermatological support yields the best outcomes [2].

Psychological FactorEffect On Skin
StressElevated cortisol, excess oil, delayed healing
AnxietyHives, itching, skin-picking
Compulsive DisordersVisible damage from repetitive behaviours

Table 2: Psychological factors and their impact on skin condition

The Skin As A Mirror Of Mental Health

Healthy, balanced skin often reflects a calm mental state. Conversely, flare-ups, dullness, or irritation may indicate chronic stress or emotional fatigue.
Addressing mental wellness can restore visible vitality, reinforcing how the psyche manifests through skin health.

Physical Contact & Emotional Regulation

Positive physical touch releases oxytocin, reducing cortisol and fostering emotional balance [2]. Skin conditions, however, may deter touch due to fear of judgement, creating isolation. Encouraging supportive environments helps individuals reclaim confidence and connection, improving overall wellbeing.

Image Skincare & Self-Confidence

Maintaining a consistent skincare routine promotes calm and structure, enhancing emotional control. Clinical improvement in the skin’s appearance can restore self-esteem and reduce anxiety.

Monderma’s prescription skincare, formulated by GPhC-registered prescribers, targets conditions like acne, rosacea, and hyperpigmentation, helping individuals regain confidence through visible, evidence-based results.

Why Skin Conditions Resonate Deeply

Because skin is visible, its changes can evoke social stigma or misconceptions about hygiene, especially with conditions like scabies [2]. These assumptions heighten feelings of disgust or shame, affecting personal relationships and emotional intimacy. Addressing both perception and treatment is vital to restoring trust and self-image.

Monderma’s Personalised Skincare Solutions

Monderma provides tailored prescription skincare combining actives like tretinoin, adapalene, and azelaic acid in a vegan hyaluronic base. These formulations target inflammation, pigmentation, and ageing to improve texture and tone.

By restoring the skin’s health, these treatments help rebuild confidence and support emotional wellbeing.

Strategies For Managing The Skin–Psyche Connection

Holistic Skincare Approach

Combining dermatological care with mental health strategies offers lasting results. Balanced nutrition, exercise, and sufficient sleep enhance both skin repair and emotional regulation [2].

Stress Management Techniques

Mindfulness, meditation, and yoga reduce stress hormones and improve inflammatory responses. Regular practice supports both clearer skin and improved mental stability [9].

Professional Support

Joint care from dermatologists and psychologists helps address both emotional and physical symptoms. Therapy alleviates anxiety and shame, while medical care resolves visible lesions, breaking the stress–skin cycle.

Conclusion: Embracing The Skin–Mind Connection

The link between skin and psyche is profound. Emotions influence inflammation, while visible conditions shape confidence. Through personalised skincare, stress management, and professional guidance, individuals can achieve both healthy skin and balanced mental health.

Discover how Monderma’s personalised formulas can support your journey, and share this article to help others understand the emotional impact of skincare.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. Dalgard FJ, Gieler U, Tomas-Aragones L, et al. The Psychological Burden of Skin Diseases: A Cross-Sectional Multicenter Study. J Invest Dermatol. 2015.
  2. Exploring the Mind–Skin Dynamics of Psychodermatology. Medical Research Archives. 2024;12(11).
  3. NICE. Acne Vulgaris: Management. 2021.
  4. Bang CH, Jeon C, Kim SH, et al. Association of Psoriasis With Mental Health Disorders. JAMA Dermatol. 2019.
  5. NHS. Rosacea Overview. 2023.
  6. Gupta MA, Gilchrest BA. Psychosocial Aspects of Aging Skin. Dermatol Clin. 2005.
  7. Platsidaki E, Efstathiou V, Markantoni V, et al. Self-Esteem, Depression, Anxiety and Quality of Life in Melasma Patients. Dermatol Ther (Heidelb). 2023.
  8. Dalgard FJ, et al. Prevalence of Anxiety Disorders in Dermatology Outpatients. J Eur Acad Dermatol Venereol. 2023.
  9. Pascoe MC, et al. Mindfulness Mediates the Physiological Markers of Stress. J Psychiatr Res. 2017.
Categories
Ingredients

Niacinamide Benefits, Uses, & More

Niacinamide, a form of vitamin B3, has become a cornerstone ingredient in modern skincare. With strong clinical backing, it benefits all skin types by soothing irritation, reducing hyperpigmentation, and strengthening the skin barrier.

This article explores how niacinamide works, its proven benefits, and how to incorporate it into your daily skincare routine effectively.

What Is Niacinamide?

Niacinamide, also called nicotinamide, is a vitamin B3 derivative essential for maintaining healthy skin and cellular energy. Found in serums, moisturisers, and prescription formulas, it offers a range of benefits supported by scientific evidence [1].

Healthcare professionals recommend niacinamide for various skin concerns, including redness, sensitivity, and pigmentation, because it is effective yet gentle enough for consistent use.

Understanding Vitamin B3

Vitamin B3 supports vital skin processes by fueling nicotinamide adenine dinucleotide (NAD⁺), a molecule crucial for DNA repair and cellular regeneration [2]. Topically, niacinamide enhances repair mechanisms, boosting overall skin resilience and texture.

How Niacinamide Penetrates Skin

Niacinamide’s water-soluble structure allows deep penetration into the skin’s layers, supporting ceramide production and barrier repair. A 2000 British Journal of Dermatology study confirmed that it significantly increased ceramide synthesis, improving hydration and protection against environmental stressors [3].

A Brief History Of Niacinamide

First identified in the 1930s as a treatment for pellagra, a severe vitamin B3 deficiency, niacinamide was established as an essential nutrient by Elvehjem et al. in 1937 [4]. Its modern application in skincare stems from these restorative properties, which now benefit people with oily, dry, or sensitive skin.

Key Benefits Of Niacinamide

Niacinamide is one of the most versatile ingredients in dermatology, improving multiple skin functions simultaneously.

Reducing Fine Lines & Wrinkles

Niacinamide promotes collagen production, improving firmness and elasticity. A 2005 Dermatologic Surgery study recorded a 21% reduction in fine lines after 12 weeks using 5% niacinamide [6].

Boosting Collagen & Elasticity

By stimulating fibroblast activity, niacinamide helps maintain structural proteins. The same study observed improved skin elasticity and smoothness, key markers of youthful skin [6].

Shielding From Environmental Damage

As an antioxidant, niacinamide defends against UV and pollution-induced oxidative stress. A review reported a 15% reduction in UV-induced immunosuppression, highlighting its photoprotective benefits [7].

Improving Skin Tone & Brightness

Niacinamide reduces dark spots by slowing melanin transfer. A clinical trial showed significant brightening within 8 weeks using 4% niacinamide [8].

Tackling Hyperpigmentation

In melasma management, niacinamide performed comparably to hydroquinone in a randomised clinical trial, offering a safer long-term alternative [8].

Enhancing Hydration

By supporting lipid barrier function, niacinamide improves moisture retention. Studies show a notable rise in skin hydration with as little as 2% concentration [9].

BenefitMechanismVisible Results
Fine Line ReductionBoosts collagen synthesis21% decrease in 12 weeks [6]
Improved ElasticityStimulates fibroblastsNoticeable firmness in 8–12 weeks [6]
UV ProtectionAntioxidant & immune support15% reduced UV-induced damage [7]
Brightening & ToneInhibits melanin transferEven tone in 8 weeks [8]
HydrationStrengthens ceramide barrierSofter skin in 4 weeks [9]

Table 1: Niacinamide benefits and clinically observed outcomes

How To Use Niacinamide In Your Skincare Routine

Incorporating niacinamide into your skincare routine is simple and effective when used correctly.

Choosing Niacinamide Products

Opt for formulations containing 2–5% niacinamide, as higher concentrations rarely offer added benefit and may increase irritation [10]. Serums are ideal for oily or combination skin, while creams work well for drier skin.

Application Tips

Apply niacinamide serum after cleansing and before heavier creams. Use gentle upward motions on the face and neck, twice daily for best results.

Layering Order Example:

StepPurposeExample Product
CleanserRemoves dirt & oilGentle Foaming Cleanser
Niacinamide SerumEnhances barrier & tone5% Niacinamide Serum
MoisturiserLocks in hydrationLightweight Cream
Sunscreen (AM)Protects from UVSPF 30+ Broad Spectrum

Table 2: Recommended layering order and application steps for niacinamide

Layering Tips

  • Pair with hyaluronic acid for extra hydration.
  • Use with retinoids in alternating routines for anti-ageing synergy.
  • Always patch test before mixing new actives.

Who Benefits Most From Niacinamide?

Niacinamide suits all skin types, including sensitive and acne-prone skin. Its anti-inflammatory action helps calm redness and strengthen the barrier.
A Cutis study found niacinamide moisturisers improved rosacea-related redness and barrier function within 4 weeks [5].

Additionally, a 2015 New England Journal of Medicine study found that 500 mg oral niacinamide twice daily reduced the risk of nonmelanoma skin cancers by 23% in high-risk patients [11].

What Results To Expect

Visible improvements in tone, hydration, and texture occur gradually with consistent use.

TimelineExpected Results
4 WeeksBrighter tone, less redness
8 WeeksImproved texture, reduced pigmentation
12 WeeksFewer fine lines, firmer appearance

Table 3: Expected skincare results over a 12-week period

Potential Side Effects

Niacinamide is well-tolerated, with mild irritation rare below 5% concentration [10]. For sensitive users, start at 2% strength and increase as skin adjusts.

Conclusion

Niacinamide delivers proven, multi-dimensional benefits, particularly hydration, tone correction, barrier repair, and fine-line reduction. It is a safe, evidence-based addition to any skincare routine and suitable for all skin types.

For those seeking expert guidance, Monderma’s personalised skincare combines niacinamide with actives like tretinoin and azelaic acid, tailored by GPhC-registered prescribers. Start your free consultation to find your perfect formula and share this guide to help others discover niacinamide’s transformative potential.

Bibliography

  1. NHS. B Vitamins and Folic Acid. 2024.
  2. NIH. Niacin – Health Professional Fact Sheet.
  3. Tanno H, et al. Nicotinamide Increases Biosynthesis of Ceramides. Br J Dermatol. 2000.
  4. Elvehjem CA, et al. Conrad Arnold Elvehjem. J Am Chem Soc. 1937.
  5. Draelos ZD, Ertel K, Berge C. Niacinamide-Containing Facial Moisturizer Benefits Subjects with Rosacea. Cutis. 2005.
  6. Bissett DL, et al. Niacinamide: A B Vitamin That Improves Aging Facial Skin. Dermatol Surg. 2005.
  7. Snaidr VA, Damian DL, Halliday GM. Nicotinamide for Photoprotection. Exp Dermatol. 2019.
  8. Navarrete-Solís J, et al. Niacinamide 4% vs Hydroquinone 4% in Melasma. Dermatol Res Pract. 2011.
  9. Gehring W. Nicotinic Acid/Niacinamide and the Skin. J Cosmet Dermatol. 2004.
  10. Cosmetic Ingredient Review. Safety Assessment of Niacinamide. 2005.
  11. Starr P. Oral Nicotinamide Prevents Common Skin Cancers. NEJM. 2015.
  12. Healthline. Niacinamide: Skin Benefits, Risks, and More. 2018.
Categories
Treatments

Understanding Cystic Acne: Causes & Treatments

Cystic acne is one of the most severe forms of acne vulgaris, developing deep beneath the skin and often leading to pain, swelling, and long-term scarring if untreated.

In this article, we discuss the causes, healing stages, and effective management strategies that can help reduce flare-ups and support long-term skin health.

What Is Cystic Acne?

Cystic acne involves large, pus-filled cysts that form deep within the skin, unlike surface-level blackheads or whiteheads. These lesions can persist for weeks or even months and often leave scars due to their depth [1].

Cystic acne affects around 9% of the global population, primarily adolescents aged 12 to 24 years [2]. It’s less common than mild acne but significantly more severe, often requiring medical attention and prescription treatments.

Causes Of Cystic Acne

Cystic acne arises when pores become blocked with excess oil, bacteria (Cutibacterium acnes), and dead skin cells. This blockage leads to inflammation, swelling, and deep cyst formation [3].

CauseDetails
Hormonal ChangesHormonal fluctuations during puberty, menstrual cycles, or PCOS increase androgens, raising sebum levels [4].
GeneticsA family history of cystic acne raises risk due to inherited oil production and inflammatory tendencies [3].
DietHigh-glycaemic foods and dairy products may worsen acne, though evidence remains mixed [5].
StressElevated cortisol can stimulate oil glands and aggravate inflammation [3].

Table 1: Common causes and contributing factors of cystic acne

Healing Stages Of Cystic Acne

Recognising the stages of cystic acne supports better treatment timing and scar prevention.

StageCharacteristicsManagement Tips
Early StageA red, tender lump begins forming beneath the skin.Avoid squeezing; use gentle cleansers and apply topical antibacterial agents [1,3].
Active StageThe cyst enlarges, becoming inflamed and painful.Topical antibiotics or retinoids help reduce inflammation; consult a dermatologist for severe cases [4].
Healing StageThe cyst shrinks, pain reduces, and pigmentation may appear.Use non-comedogenic moisturisers and SPF to reduce hyperpigmentation risk [5].

Table 2: Stages of cystic acne and recommended management approaches

Effective Cystic Acne Treatments

Cystic acne often requires a combination of topical and oral treatments to control inflammation, reduce bacteria, and balance oil production.

Topical Treatments

Benzoyl Peroxide
Reduces bacteria and inflammation. Studies show a 63% lesion reduction after 12 weeks of tretinoin gel use; combining benzoyl peroxide with retinoids enhances results [6].

Salicylic Acid
Unclogs pores and exfoliates surface layers, improving mild to moderate acne [4]. Best used alongside other treatments for deeper cysts.

Topical Retinoids (Adapalene, Tretinoin)
Promote cell turnover and prevent pore blockage. Adapalene 0.1% with benzoyl peroxide 2.5% is a recommended first-line therapy for mild to moderate acne [6].

Azelaic Acid
Gentle and safe for sensitive or pregnant patients, offering antimicrobial and anti-inflammatory benefits. It also helps fade post-inflammatory hyperpigmentation [4,5].

Oral Medications

Oral Antibiotics (e.g., Doxycycline)
Reduce bacteria and inflammation. Typically prescribed for up to 3 months alongside topical treatments to avoid antibiotic resistance [5].

Combined Oral Contraceptives
Help regulate hormone levels and reduce sebum production in women with hormonal acne [2].

Isotretinoin
A potent retinoid that drastically reduces oil production and acne lesions. Reserved for severe or resistant cystic acne due to side effects and monitoring needs [3].

Lifestyle & Home Remedies

Dietary Adjustments
Reducing dairy and high-glycaemic foods may improve acne in some individuals, though responses vary [5].

Stress Management
Meditation, exercise, and mindfulness may indirectly help regulate oil production by reducing cortisol [3].

Skincare Routine
Use gentle, non-comedogenic cleansers and moisturisers. Avoid harsh scrubs or alcohol-based toners that can worsen irritation [5].

Treating Acne Scars

Cystic acne can cause scarring, especially if cysts are picked or squeezed. Dermatological procedures can improve texture and tone.

TreatmentMechanismBenefitsConsiderations
Chemical PeelsRemove surface layers with acids like salicylic or glycolic [3].Improves texture and hyperpigmentation.May cause irritation; multiple sessions needed.
Laser TherapyStimulates collagen regeneration.Effective for deep scars.Higher cost; requires specialist.
MicroneedlingPromotes collagen to smooth skin texture [3].Minimally invasive, effective for rolling scars.Several sessions required.
Home TreatmentsSilicone sheets and vitamin C serums may fade scars [5].Accessible and non-invasive.Gradual results.

Table 3: Treatment options for improving acne scars

Monderma’s Personalised Skincare Solutions

Monderma provides prescription-strength skincare tailored to acne, pigmentation, and rosacea. Custom formulations may include:

  • Adapalene or Tretinoin for cell turnover.
  • Azelaic Acid or Clindamycin to reduce bacteria and inflammation.
  • Niacinamide to strengthen the skin barrier and soothe irritation.

Each prescription is reviewed by GPhC-registered prescribers to ensure safety and effectiveness. Through a free consultation, Monderma designs bespoke regimens that align with dermatological guidelines.

When To See A Dermatologist

Seek professional advice if:

  • Acne is painful, cystic, or leaves scarring.
  • Over-the-counter treatments fail after several months.
  • Breakouts cause emotional distress or self-esteem issues.

NICE recommends referral for nodulocystic acne unresponsive to two 4–6-month treatment courses or causing severe distress [5]. Dermatologists can prescribe isotretinoin or advanced therapies when appropriate.

Conclusion

Cystic acne requires a comprehensive approach that combines medical treatments, skincare, and lifestyle management. Understanding its causes and healing stages helps control flare-ups, reduce scarring, and improve skin health.

For evidence-based, tailored skincare, Monderma offers free consultations to create personalised regimens that target cystic acne safely and effectively. Share this article to help others manage acne confidently and find solutions backed by clinical expertise.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. StatPearls. Acne Vulgaris. NCBI Bookshelf. Updated 2023.
  2. Eichenfield DZ, Sprague J, Eichenfield LF. Management of Acne Vulgaris: A Review. JAMA. 2021;326(20):2055–2067.
  3. Zaenglein AL, et al. Guidelines of Care for the Management of Acne Vulgaris. J Am Acad Dermatol. 2016;74(5):945–973.
  4. Reynolds RV, et al. Guidelines of Care for the Management of Acne Vulgaris. J Am Acad Dermatol. 2024;90(5):1006.e1–1006.e30.
  5. National Institute for Health and Care Excellence (NICE). Acne Vulgaris: Management. NG198. 2021.
  6. Chandrashekhar BS, et al. Tretinoin Nanogel 0.025% Versus Conventional Gel 0.025% in Acne Treatment. Indian J Dermatol. 2015;60(5):520.
Categories
Miscellaneous

K-Beauty & The Secrets Behind The Glass Skin Look

K-beauty, short for Korean beauty, has revolutionised skincare with its holistic focus on hydration, balance, and prevention. Known for creating the Korean glass skin look, it delivers a dewy, luminous complexion that reflects light naturally.

This guide explores the science-backed 10-step Korean skincare routine, revealing how consistent, gentle care transforms skin into its healthiest state.

The History Of Korean Skin Care & What Sets It Apart

K-beauty’s roots extend centuries, using natural ingredients like ginseng, green tea, and rice water. In the 2000s, Korea’s beauty industry combined traditional botanicals with scientific innovation, becoming one of the top 10 global skincare markets [1].

Unlike Western approaches that focus on corrective treatments for acne-prone or damaged skin, Korean skincare prioritises hydration and prevention. The result is the hallmark glass skin effect that is smooth, reflective, and healthy.

What Is Korean Glass Skin?

Glass skin refers to a hydrated, even-toned, and radiant complexion that looks translucent and naturally luminous. It’s achieved through layered hydration, not heavy makeup.

Studies confirm that increasing skin hydration visibly reduces fine lines and improves texture, supporting the glass skin goal [3]. With consistent care, results are visible within 4–6 weeks.

The 10-Step K-Beauty Routine For Glass Skin

The 10-step K-beauty method layers products from lightest to thickest, enhancing absorption and moisture retention [2]. While not every step is required daily, consistency drives lasting results.

StepPurposeRecommended Use
1. Oil-Based CleanserRemoves makeup & sunscreen effectively [4].Nightly, if makeup or SPF is used.
2. Water-Based CleanserClears sweat & impurities for a clean base.Daily.
3. ExfoliationSmooths texture & encourages cell renewal [5].2–3 times weekly.
4. Hydrating TonerRestores pH & boosts hydration [3].Daily.
5. EssenceDeeply hydrates & supports elasticity.3–5 times weekly.
6. SerumTargets pigmentation & brightens tone [6].Daily.
7. Sheet MaskDelivers intensive hydration & glow.1–2 times weekly.
8. Eye CreamMoisturises delicate skin & softens lines.2–3 times weekly.
9. MoisturiserLocks in hydration & smooths texture.Daily.
10. Sunscreen (Day) / Night Cream (Night)Protects against UV damage or supports recovery [7].SPF daily; night cream optional.

Table 1: Steps and purposes of the Korean glass skin routine

Key Steps Explained

Step 1 & 2: Double Cleansing

The cornerstone of K-beauty. Oil-based cleansers dissolve makeup and sunscreen, while water-based cleansers remove sweat and debris. Clinical findings confirm oil cleansers outperform water alone in removing sunscreen [4].

Step 3: Gentle Exfoliation

Use mild acids such as AHA or BHA to remove dead cells and smooth texture. Over-exfoliation can irritate; limit to 2–3 times weekly for balance [5].

Step 4: Hydrating Toner

Toners with hyaluronic acid or glycerin restore the skin’s pH and lock in moisture [3]. Apply daily using your palms for better absorption.

Step 5: Essence

Essences, unique to K-beauty, combine toner-like hydration with serum-level actives. Ingredients like snail mucin support collagen synthesis and skin repair.

Step 6: Serum

Niacinamide or vitamin C serums fade pigmentation and improve tone. Clinical studies confirm niacinamide reduces hyperpigmentation and supports barrier function [6].

Step 7: Sheet Mask

Infused with hydrating ingredients like green tea or ceramides, sheet masks enhance radiance and plumpness. Use 1–2 times weekly for an extra glow boost.

Step 8: Eye Cream

Retinol or peptide eye creams minimise fine lines and dryness around delicate eye areas. Avoid daily use if sensitivity occurs.

Step 9: Moisturiser

Light gels suit oily skin, while rich creams support dry skin. Moisturising is key for maintaining the hydrated look central to the glass skin aesthetic.

Step 10: Sunscreen or Night Cream

SPF 30+ shields from UV rays, a non-negotiable for preventing photoaging and pigmentation [7]. At night, swap for a nourishing cream to support recovery.

Practical Tips For Success

  • Layer products correctly: Apply from thinnest to thickest for optimal absorption [2].
  • Patch test new formulas: Especially when using actives like retinol or vitamin C.
  • Be consistent: Hydration and tone improvements appear gradually within 4–6 weeks.
  • Avoid harsh ingredients: Overuse of acids or alcohol-based toners can disrupt skin balance.

Glass Skin Makeup Tips

Glass skin is best enhanced, not hidden. Start with a light primer, apply a sheer foundation or BB cream, and use cream-based highlighters for a dewy glow. Focus on luminosity, not coverage.

Common Mistakes To Avoid

  • Skipping sunscreen: UV rays cause damage even indoors [7].
  • Over-exfoliating: Strips the skin’s barrier and reduces hydration.
  • Mixing too many actives: Combining strong acids and retinoids can irritate.

Conclusion

K-beauty’s 10-step skincare routine creates the sought-after glass skin by layering hydration, protection, and nourishment. Each product works synergistically to brighten tone, improve elasticity, and achieve a smooth, radiant glow.

To elevate your skincare journey, explore Monderma’s prescription-strength solutions that complement K-beauty hydration principles. Start with a free consultation to receive a personalised plan, and share this guide to help others achieve their perfect glass skin glow.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. Korea Trade-Investment Promotion Agency (KOTRA). Status and Prospects of the South Korean Cosmetics Industry. 2019.
  2. PureVictoria. How to Layer Skincare Products for Maximum Effectiveness. 2025.
  3. Draelos ZD, et al. Efficacy Evaluation of a Topical Hyaluronic Acid Serum in Facial Photoaging. Dermatol Ther (Heidelb). 2021;11(4):1385–1394.
  4. Chen W, et al. The Optimal Cleansing Method for the Removal of Sunscreen: Water, Cleanser or Cleansing Oil? J Cosmet Dermatol. 2020;19(1):180–184.
  5. Park JY, et al. Insights on Skin Quality and Clinical Practice Trends in Asia Pacific. J Clin Aesthet Dermatol. 2022;15(6):10–21.
  6. Hakozaki T, et al. The Effect of Niacinamide on Reducing Cutaneous Pigmentation. Br J Dermatol. 2002;147(2):20–31.
  7. Guan LL, et al. Sunscreens and Photoaging: A Review of Current Literature. Am J Clin Dermatol. 2021;22(6):819–828.
Categories
Ingredients

Microneedling & Hyaluronic Acid Duo Guide

Microneedling and hyaluronic acid form a clinically supported skincare combination that enhances skin rejuvenation, hydration, and texture. This synergy works by stimulating collagen production while replenishing moisture, leading to smoother and more radiant skin.

In this guide, we explore how this combination is particularly effective for improving fine lines, scars, and uneven tone, with research showing that up to 80% of patients report visible improvement after multiple sessions.

What Is Microneedling?

Microneedling, or collagen induction therapy, uses fine sterile needles to create micro-injuries in the skin, activating the body’s natural healing process. This stimulates collagen and elastin production, which strengthens skin structure and promotes firmness [1,2].

The treatment is widely used for improving acne scars, fine lines, and overall tone. Studies confirm that microneedling can improve texture by up to 80% with consistent sessions [5]. It offers rejuvenation without surgery or extended downtime.

How Microneedling Works

The process involves a controlled puncturing technique that initiates wound healing in three stages: inflammation, proliferation, and tissue remodelling [1,2]. During this process, the skin produces new collagen and capillaries, reducing scarring and restoring elasticity.

The treatment also enhances the delivery of active ingredients applied afterward, particularly hydrating compounds like hyaluronic acid, which penetrate more effectively through the microchannels created.

Introduction To Hyaluronic Acid

Hyaluronic acid (HA) is a naturally occurring molecule in the skin known for its exceptional ability to hold water, up to 1,000 times its weight [3,4]. It helps maintain hydration, elasticity, and barrier integrity.

As natural HA levels decline with age, topical application replenishes moisture and improves skin plumpness. Using a hyaluronic acid serum for microneedling boosts both hydration and skin repair [3,4,9].

The Science Behind Hyaluronic Acid

Hyaluronic acid binds water molecules, maintaining skin smoothness and supporting cell repair [3,4]. When applied after microneedling, it penetrates deeply through the microchannels created during treatment, amplifying its hydrating and soothing effects [6,7,8].

Topical HA also enhances the skin’s recovery process, reducing dryness and redness while promoting faster regeneration [9,10,11].

Synergising Microneedling & Hyaluronic Acid

Combining microneedling and hyaluronic acid optimises hydration, collagen synthesis, and overall rejuvenation.

Enhanced Absorption

Microneedling forms microchannels that significantly increase the penetration of topical agents. When HA is applied post-treatment, it reaches deeper skin layers, improving hydration and elasticity [6,7,8].

Accelerated Healing & Hydration

The skin may experience mild irritation or dryness after microneedling. Hyaluronic acid immediately restores hydration and soothes sensitivity, helping the skin recover faster [9,10,11].

Improved Skin Texture & Tone

Collagen stimulation from microneedling, combined with HA’s moisture-binding effect, refines texture and enhances tone [1,2,9]. Clinical findings show significant hydration gains following treatment cycles [10,11].

BenefitSummary
Enhanced AbsorptionMicroneedling boosts hyaluronic acid delivery, improving moisture retention.
Accelerated Healing & HydrationHA calms irritation and supports post-procedure healing.
Improved Texture & ToneCombined effects smooth skin and increase radiance.

Table 1: Combined benefits of microneedling and hyaluronic acid

Optimising Hyaluronic Acid For Microneedling

Selecting a suitable HA serum is essential to maximise results:

Look For High-Quality Ingredients

Choose pure hyaluronic acid serums free from fragrance or alcohol to avoid irritation [3,4,9].

Check The Molecular Weight

Low molecular weight HA penetrates deeper, while high molecular weight HA retains surface hydration. A dual-weight formulation balances both effects [2,11].

Consider The Formulation

Use serums designed specifically for post-microneedling use, as these are gentle and support barrier recovery [9,10,11].

Integrating Microneedling & Hyaluronic Acid Into Your Routine

Adding microneedling with HA to your skincare routine promotes long-term skin rejuvenation. Continued use of HA serums after each session maintains moisture levels and collagen synthesis [9,10,11].

Avoid using active ingredients such as retinoids or exfoliating acids for several days post-treatment to prevent irritation [12–15]. Consulting professionals, like Monderma’s experts, ensures proper guidance for safe integration and product selection.

Post-Microneedling Care With Hyaluronic Acid

After treatment, appropriate care is key to achieving the best results:

  • Immediate Application: Apply HA serum immediately post-procedure to maximise penetration [9–13].
  • Keep Skin Hydrated: Reapply HA daily for several days to maintain hydration and aid tissue repair [9–11].
  • Avoid Harsh Products: Skip exfoliants and active acids for at least a week to avoid sensitivity [12–14].

Following these steps supports optimal recovery and maintains smoother, radiant skin.

Maximising Results With Professional Guidance

Professional assessment helps customise treatment frequency and serum formulation. Skincare experts ensure that HA products are compatible with skin sensitivity and microneedling depth, reducing risk and enhancing benefits [13].

This personalised approach ensures optimal hydration, faster healing, and improved tone with each session.

Monderma’s Personalised Skincare Solutions

Monderma offers prescription skincare tailored to skin health needs such as ageing, acne, and pigmentation. Its vegan formulations often include hyaluronic acid alongside actives like tretinoin or niacinamide to enhance hydration and regeneration.

Following a consultation, Monderma’s GPhC-registered prescribers design custom blends that complement treatments like microneedling, helping users achieve visible results within weeks.

Conclusion

Microneedling and hyaluronic acid together create a science-backed method for achieving smoother, hydrated, and more radiant skin. Microneedling stimulates collagen, while HA replenishes moisture and speeds recovery, making them a powerful anti-ageing combination [1,2,9].

Choosing high-quality HA products and following expert-guided post-care, such as through Monderma’s tailored consultations, maximises results. Share this article to help others discover how microneedling with hyaluronic acid can revitalise their complexion.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. StatPearls. Microneedling. 2024.
  2. Hamed R, et al. Recent Advances in Microneedling-Assisted Cosmetic Procedures. Cosmetics. 2024;11(2):51.
  3. Singh A, Yadav S. Microneedling: Advances and Widening Horizons. Indian Dermatol Online J. 2016;7(4):244–254.
  4. Papakonstantinou E, et al. Hyaluronic Acid: A Key Molecule in Skin Aging. Dermato-Endocrinology. 2012;4(3):253–258.
  5. Jaiswal S, et al. Microneedling in Dermatology: A Comprehensive Review. Cureus. 2024;16(9):e51432.
  6. Prausnitz MR, Langer R. Transdermal Drug Delivery. Nat Biotechnol. 2008;26(11):1261–1268.
  7. Essendoubi M, et al. Human Skin Penetration of Hyaluronic Acid of Different Molecular Weights. Skin Res Technol. 2016;22(1):55–62.
  8. Juniper Publishers. Skin Penetration Ability of 12 Hyaluronic Acids with Different Molecular Weights.
  9. Jegasothy SM, et al. Efficacy of a New Topical Nano-Hyaluronic Acid in Humans. J Clin Aesthet Dermatol. 2016;9(3):25–29.
  10. Healthline. How to Take Care of Your Skin After Microneedling.
  11. Zensa Skincare. Microneedling After-Care.
  12. Monderma. Prescription Skincare.
  13. Professional Beauty. Microneedling: Everything You Need to Know.
Categories
Treatments

Prescription Face Cream For Rosacea Options

Rosacea is a chronic inflammatory skin condition marked by facial redness, visible blood vessels, and sometimes pustules. It is often mistaken for acne but has distinct triggers and mechanisms involving inflammation and vascular changes.

In this article, we explore how prescription face creams can significantly reduce symptoms, restoring skin comfort and confidence when used under medical guidance.

Common Symptoms Of Rosacea

SymptomDescription
Persistent rednessA hallmark sign, worsened by sun exposure.
SwellingInflammation leads to visible puffiness and sensitivity.
Red bumps or pustulesInflammatory lesions resembling acne.
Visible blood vesselsFine telangiectasia visible on the skin.
Eye irritationOcular rosacea causes dryness and redness.

Table 1: Common symptoms and features of rosacea

Prescription Face Creams & Inflammatory Lesions

Prescription face creams are central to rosacea management, targeting inflammation, bacterial growth, and Demodex mite overgrowth. Dermatologists prescribe these creams for long-term use, with visible improvement often seen within weeks [1].

Ivermectin For Rosacea

How Ivermectin Works

Ivermectin is a widely prescribed topical treatment for papulopustular rosacea. It reduces inflammation and eliminates Demodex mites, which are frequently linked to flare-ups [3]. Clinical results show that redness and pustules improve from week 3, with significant progress by week 16 [2].

Ivermectin also calms irritation and restores the skin barrier, making it an effective and well-tolerated option. Side effects such as mild burning or dryness are uncommon.

Other Prescription Face Creams

Metronidazole

Metronidazole cream or gel is a trusted option for reducing inflammation and facial redness. Applied once or twice daily, it is well-suited for long-term maintenance with minimal side effects.

Azelaic Acid

Azelaic acid clears pores and reduces swelling while targeting the oxidative stress that contributes to flare-ups. Studies show visible improvements in inflammatory lesions within 12–15 weeks of treatment [4]. It is suitable for sensitive skin and mild rosacea cases.

Niacinamide

Niacinamide (vitamin B3) is not a prescription-only ingredient but is often combined with medical creams for its anti-inflammatory and barrier-strengthening effects. It supports recovery, reduces redness, and improves moisture balance [5].

IngredientPrimary ActionEffect on Rosacea
IvermectinAnti-inflammatory, reduces Demodex mitesCalms redness and pustules
MetronidazoleAntimicrobial and anti-inflammatoryReduces swelling and redness
Azelaic AcidClears pores, reduces oxidative stressImproves texture and prevents flare-ups
NiacinamideStrengthens barrier, reduces rednessEnhances hydration and skin resilience

Table 2: Key active ingredients and their effects on rosacea

Monderma’s Personalised Prescription Face Creams

Monderma provides prescription-strength, dermatologist-supervised formulas that combine ivermectin, azelaic acid, and niacinamide. After a free online consultation, prescribers adjust strengths to suit individual skin sensitivity and symptom severity.

This tailored approach ensures balanced efficacy and tolerability. Results may be noticed within the first week, with greater improvement over several weeks as inflammation decreases and redness fades.

Combining Treatments For Enhanced Results

Combining topical treatments with procedural therapies can improve skin texture and reduce visible vessels. Laser therapy complements prescription face creams by addressing redness and telangiectasia directly.

Laser Treatment For Rosacea

Laser therapy uses focused light to constrict dilated blood vessels, reducing visible redness and improving tone. The NHS highlights that results can last for several months following a short series of treatments, depending on the individual [6]. Temporary redness or mild swelling may occur but typically resolves quickly.

Managing Rosacea With A Skincare Routine

Supporting prescription treatments with a consistent skincare routine helps maintain results and reduce flare-ups:

  • Avoid triggers such as alcohol, spicy foods, and excessive sun exposure.
  • Use gentle, fragrance-free cleansers and moisturisers.
  • Apply SPF 30 or higher daily to prevent flare-ups.
  • Stay hydrated and incorporate anti-inflammatory foods like omega-3-rich fish.

These daily habits strengthen skin resilience and complement medical therapies.

Conclusion

Prescription face creams such as ivermectin, metronidazole, and azelaic acid remain effective treatments for managing rosacea. When combined with niacinamide, laser therapy, and consistent skincare, they significantly reduce redness, pustules, and inflammation.

Monderma’s personalised formulas offer an accessible and evidence-based solution for those seeking expert care without long waiting times. Explore a free consultation today and take the first step toward calmer, healthier skin.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. National Institute for Health and Care Excellence (NICE). Rosacea. NICE Clinical Knowledge Summaries, 2023.
  2. Taieb A, et al. Superiority of Ivermectin 1% Cream Over Metronidazole 0.75% Cream in Treating Rosacea. JAMA Dermatol. 2015;151(11):1212–1218.
  3. Forton F, Seys B. Density of Demodex Folliculorum in Rosacea: A Case-Control Study. Br J Dermatol. 1993;128(6):650–659.
  4. Liu RH, et al. Azelaic Acid in the Treatment of Papulopustular Rosacea: A Systematic Review. Arch Dermatol. 2006;142(8):1047–1052.
  5. Marques C, et al. Mechanistic Insights into the Multiple Functions of Niacinamide. Int J Mol Sci. 2024;25(7):3140.
  6. NHS. Laser Treatment for Rosacea. NHS Bristol Laser Centre, 2025.
Categories
Miscellaneous

Skin Analysis Online Vs In Person

Skin analysis is evolving as digital healthcare reshapes how people access dermatology. Both online and in-person consultations provide effective routes to identify and treat conditions like acne, pigmentation, and ageing. Each has its advantages and challenges, and a hybrid model can deliver the most balanced, personalised skincare experience.

This article compares both methods using research-based evidence, helping readers choose the best path for their needs. Services like Monderma integrate dermatologist oversight with online convenience, aligning with NHS goals to reduce waiting times and improve access to care.

Understanding Skin Analysis

Skin analysis involves examining the skin’s texture, hydration, tone, and overall health to detect conditions such as acne, dryness, rosacea, and early signs of skin cancer. Dermatologists and skincare professionals use this assessment to tailor treatments for each patient’s needs.

Early diagnosis is key. In England, more than 17,500 people are diagnosed with skin cancer every year [1]. Thorough analysis helps catch these changes early and supports preventive care. A British Journal of Dermatology study confirmed that detailed assessments improve treatment adherence and long-term results for chronic conditions such as psoriasis [2].

The Rise Of Online Skin Analysis

Convenience & Accessibility

Online skin analysis allows patients to submit photos or answer guided questionnaires remotely. It removes the need for travel, saving time and improving access for people in rural areas.

NHS England reports that teledermatology services have reduced outpatient dermatology visits by up to 30% [3]. Digital providers like Monderma enhance accessibility through free consultations reviewed by qualified prescribers within 24 hours.

Long NHS waiting lists with many patients waiting over 18 weeks for an appointment highlight the role of online services in bridging care gaps [4].

The Role Of Technology In Future Healthcare

Artificial intelligence (AI) and machine learning now support dermatologists by analysing high-resolution skin images. In trials, AI achieved a 97% sensitivity rate in melanoma detection, comparable to specialist accuracy [5]. This improves early detection and helps triage cases faster, optimising dermatology workloads.

Personalised Skincare Recommendations

Online consultations use data and imaging to produce personalised skincare plans. These may include ingredient-based product recommendations or prescription treatments tailored to skin concerns like acne or hyperpigmentation.

A 2022 Frontiers in Medicine review found digital interventions improved satisfaction and adherence for people with skin conditions [6]. Monderma’s platform follows this model, offering prescription formulations with ingredients such as tretinoin, azelaic acid, or adapalene, based on individual skin profiles.

FeatureOnline Skin AnalysisIn-Person Consultation
AccessibilityAvailable from home on any device.Requires appointment and clinic visit.
SpeedResults typically within 24–48 hours.May involve longer waiting times.
TechnologyUses AI imaging and digital triage.Includes direct dermoscopic evaluation.
SuitabilityIdeal for mild or routine conditions.Best for complex or evolving concerns.

Table 1: Online analysis compared to in-person consultations

Problems Faced By NHS Dermatology

NHS dermatology faces ongoing challenges including limited specialist availability and long waiting lists. With only around 650 consultant dermatologists across the UK [1], demand often outpaces capacity.

Some patients wait up to two years for specialist appointments [4]. Online consultations, such as those offered by Monderma, help alleviate pressure by supporting mild to moderate skin concerns remotely, freeing specialists to manage urgent cases.

Monderma: Personalised Skincare Solutions

Monderma provides personalised, dermatologist-tested skincare for acne, ageing, pigmentation, and rosacea. After completing a free online consultation, each patient receives a tailored treatment plan created by a GPhC-registered prescriber.

Common active ingredients include:

  • Tretinoin for cell renewal and collagen support.
  • Azelaic acid to reduce pigmentation and inflammation.
  • Adapalene to prevent clogged pores and smooth skin.

This hybrid model combines prescription precision with digital convenience, improving accessibility for those who might otherwise face long waiting times.

Making The Right Choice: Online & In-Person

Choosing between online and in-person consultations depends on the individual’s needs and the complexity of the condition:

  • Online analysis suits common concerns like mild acne or skin texture issues.
  • In-person reviews are necessary for changing moles, severe inflammation, or uncertain diagnoses.

A hybrid approach combining both models offers the most comprehensive care, ensuring convenient access with specialist validation when required. This balance supports both patients and healthcare systems.

The Future Of Skin Analysis

AI-driven technology and telemedicine continue to expand dermatology access. Future innovations may include real-time lesion tracking and virtual 3D skin modelling, improving diagnostic accuracy and care quality.

Platforms like Monderma demonstrate how remote dermatology can coexist with traditional care, creating a flexible and efficient patient pathway. Sharing this article can help others discover safe, accessible skincare guided by professional expertise.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. Cancer Research UK. Seeing Your GP About Skin Cancer. Accessed 2025.
  2. Nelson PA, et al. Clinicians’ Views of Supporting Lifestyle Behaviour Change in Patients with Psoriasis. Br J Dermatol. 2014;171:1116–22.
  3. NHS England. A Teledermatology Roadmap: Implementing Safe & Effective Teledermatology Triage Pathways. 2023.
  4. Skin Analytics. Manchester University NHS Foundation Trust Launches AI Dermatology. 2024.
  5. Advancing Skin Cancer Detection with Artificial Intelligence: UKRI Competition Results. Br J Dermatol. Supplement 1, 2025.
  6. Hewitt RM, et al. A Mixed Methods Systematic Review of Digital Interventions for Dermatological Conditions. Front Med. 2022.
Categories
Ingredients

What Is Tretinoin Good For? Uses & Benefits

Tretinoin, derived from vitamin A, is a well-researched topical retinoid used to treat acne, fine lines, and uneven pigmentation. It encourages skin renewal and strengthens collagen, making it a cornerstone in dermatological care. In the UK, tretinoin is a prescription-only medicine.

This article explains its benefits, how it works, and safe application practices for best results.

Understanding Tretinoin

How Does Tretinoin Work

Tretinoin accelerates cell turnover, helping to remove dead skin cells and promote new growth. This unclogs pores, reduces acne, and smooths texture.

It also boosts collagen, improving firmness and elasticity.
A JAMA study found tretinoin visibly improved fine wrinkles and roughness after 16 weeks [1]. Another review confirmed reduced microcomedones and acne lesions within 12 weeks of consistent use [3].

Is Tretinoin A Steroid

Tretinoin is not a steroid. It belongs to the retinoid family derived from vitamin A. Unlike steroids, it does not thin the skin or cause dependency. Instead, it encourages regeneration and long-term skin health [2].

Tretinoin Benefits

Tretinoin effectively targets several common skin concerns backed by clinical research.

Tretinoin For Acne

Tretinoin clears pores by increasing cell turnover. It reduces breakouts and gradually fades acne marks. A 2017 review found retinoids like tretinoin significantly decreased acne lesions with consistent use [3].

Tretinoin For Wrinkles

The cream improves skin texture and reduces wrinkles by stimulating collagen. Studies show noticeable improvement in fine lines and elasticity after several months of use [4].

Tretinoin For Skin Discoloration

Tretinoin exfoliates pigmented cells, helping to fade dark spots caused by inflammation or sun exposure. A study showed 0.1% tretinoin lightened hyperpigmentation in Black patients over 40 weeks [5].

Overall Skin Improvement

Regular use improves texture, tone, and barrier strength. Clinical data confirm tretinoin enhances collagen synthesis and smoothness over time [4].

Skin ConditionHow It WorksOutcome
AcneSpeeds cell turnover and unclogs pores.Reduces breakouts and acne scarring.
WrinklesStimulates collagen and increases elasticity.Smooths lines and refines texture.
Skin DiscolorationExfoliates pigmented cells and renews tone.Fades dark spots and evens complexion.
Overall Skin HealthSupports collagen and skin barrier renewal.Improves tone, firmness, and radiance.

Table 1: Skin benefits and clinical effects of tretinoin

These benefits make tretinoin one of the most clinically validated ingredients for both acne management and visible skin ageing.

Tretinoin Dosage & Strengths

Best Strength Of Tretinoin Cream For Wrinkles

Tretinoin is available in concentrations from 0.025% to 0.1%. Dermatologists usually recommend starting with 0.025% to build tolerance before moving to higher strengths [6]. The optimal concentration depends on skin type and response.

How Often To Use Tretinoin

Begin with application every other night or two to three times weekly. Gradually increase to nightly use once the skin adjusts. The NHS advises applying tretinoin once daily at bedtime, reducing frequency if irritation occurs [6].

How To Apply Tretinoin Cream

Correct technique enhances results and minimises side effects:

  1. Cleanse gently and pat dry.
  2. Wait 15–20 minutes before application.
  3. Apply a pea-sized amount evenly across the face, avoiding eyes, nostrils, and mouth corners.
  4. Follow with a moisturiser to reduce dryness.
  5. Use sunscreen during the day.

Monderma’s clinicians recommend this routine to ensure effective, well-tolerated use.

Potential Side Effects Of Tretinoin

Mild side effects such as redness, peeling, dryness, or sun sensitivity are common at the start of treatment [7]. These effects usually lessen as the skin adapts.

Daily moisturising and sun protection help manage irritation. Avoid exfoliants or strong actives during early treatment weeks.

Tretinoin Results: What To Expect

Visible improvement typically appears after 6–12 weeks. Early use may cause mild breakouts, known as purging, as clogged pores clear.

The NHS notes that acne may temporarily worsen during the first 7–10 days but improves within several weeks [2,6].Consistent application delivers smoother, brighter, and clearer skin over time.

Monderma’s Expert Guidance

Tretinoin requires professional oversight for safe and effective use. Monderma offers free online consultations with GPhC-registered prescribers for UK residents.

After reviewing your skin type and history, a tailored formula is created using prescription-strength tretinoin blended with hydrating and barrier-supporting ingredients.

Conclusion

Tretinoin remains one of the most evidence-backed treatments for acne, fine lines, and uneven tone. It enhances collagen, refines texture, and promotes long-term skin renewal when used correctly.

Because it is a prescription retinoid, expert guidance can help to ensure results while minimising irritation. For personalised guidance, Monderma provides a free consultation to help users safely integrate tretinoin into their skincare routine.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. Weiss JS, et al. Topical Tretinoin Improves Photoaged Skin. JAMA. 1988;259(4):527–532.
  2. MedlinePlus. Tretinoin (Topical). U.S. National Library of Medicine.
  3. Leyden J, Stein-Gold L, Weiss J. Why Topical Retinoids Are Mainstay of Therapy for Acne. Dermatol Ther. 2017;7(3):293–304.
  4. Mukherjee S, Date A, Patravale V, et al. Retinoids in the Treatment of Skin Aging: Clinical Efficacy and Safety. Clin Interv Aging. 2006;1(4):327–348.
  5. Bulengo-Ransby SM, et al. Topical Tretinoin Therapy for Hyperpigmented Lesions. N Engl J Med. 1993;328(20):1438–1443.
  6. NHS. Acne – Treatment. Accessed July 2025.
  7. Pomerantz H. Predictors of Local Adverse Effects Caused by Topical Tretinoin Cream 0.1%. J Dermatol. 2014.
Categories
Treatments

Fibrous Papules: Causes & Treatments Explained

Fibrous papules are small, harmless skin growths that often develop on the nose or nearby facial areas. While medically benign, many people seek treatment for cosmetic reasons.

This article explains what fibrous papules are, how to distinguish them from other skin conditions, and explores safe, evidence-based treatments and aftercare options for optimal results.

What Are Fibrous Papules

Fibrous papules are firm, dome-shaped bumps made up of collagen, fibrous tissue, and blood vessels [1,9]. They typically measure 2–4 mm and vary from pink to skin-toned.

These lesions, often solitary, are a type of angiofibroma most commonly found on the nose. They are non-cancerous, painless, and do not spread or cause complications [1,9].

Causes Of Fibrous Papules

The cause of fibrous papules remains uncertain. They are believed to result from local overgrowth of fibrous tissue in the dermis, possibly involving dendritic cells [9]. Most cases occur randomly in adults without lifestyle triggers [1].

In rare instances, multiple papules can be associated with genetic conditions such as tuberous sclerosis or multiple endocrine neoplasia type 1 [2]. However, solitary lesions are far more common and unrelated to hereditary factors [1].

Fibrous Papule Vs. Basal Cell Carcinoma

Accurate differentiation between fibrous papules and basal cell carcinoma (BCC) is essential. Fibrous papules are smooth, firm, and stable in size, while BCC may bleed, crust, or enlarge over time [1,5].

Dermoscopy can help distinguish them. Fibrous papules show a uniform pink or white background with fine blood vessels, whereas BCC often exhibits pearly or pigmented features. When uncertain, dermatologists may perform a biopsy for confirmation [1].

When To Consult A Dermatologist

Although fibrous papules are benign, changes such as rapid growth, bleeding, or altered colour require professional evaluation. The NHS recommends seeking medical assessment for any changing or persistent skin lesion [5]. Early review ensures correct diagnosis and peace of mind.

Treatment Options For Fibrous Papules

Dermatological treatments for fibrous papules are usually chosen for cosmetic improvement. The best method depends on the lesion’s size, location, and skin type [1,3].

Excision

A dermatologist can remove the papule under local anaesthesia using a fine scalpel. Excision provides immediate, permanent removal with minimal scarring when performed carefully [1,3].

Cryotherapy

Cryotherapy freezes the lesion using liquid nitrogen until it detaches naturally. While safe, it is less commonly used for facial papules due to the risk of irritation or temporary pigmentation, especially in darker skin [3].

Laser Treatment

Laser therapy uses focused light to vaporise the papule with precision. Pulsed dye and CO₂ lasers are frequently used and can achieve smooth results with minimal downtime [3,4].

Electrocautery

This treatment applies controlled electrical heat to remove the papule and seal small blood vessels, reducing bleeding and supporting rapid recovery [3].

Treatment OptionSummary
ExcisionSurgical removal under local anaesthesia, highly effective with minimal scarring.
CryotherapyFreezes lesion with liquid nitrogen, less common for facial use.
Laser TreatmentUses pulsed dye or CO₂ laser for precise, quick recovery.
ElectrocauteryRemoves lesion using heat, ideal for small papules with minimal downtime.

Each approach can be effective when performed by a qualified dermatologist. Excision and laser treatment are most common for facial areas because they offer precision and predictable cosmetic outcomes.

Post-Treatment Care

After fibrous papule removal, correct aftercare supports healing and prevents pigmentation or scarring. Dermatologists generally recommend the following:

  • Gently cleanse the area with mild soap and water.
  • Apply an antibacterial ointment as advised.
  • Protect from sun exposure using SPF 30 or higher.
  • Follow all aftercare guidance from your healthcare provider.

Sun protection is especially important to reduce post-treatment pigmentation, particularly on facial skin [1].

Monderma’s Role In Post-Excision Care

After excision, personalised skincare can support recovery. Monderma’s prescription skincare, created by GPhC-registered prescribers, combines hydrating and restorative actives in a vegan base with hyaluronic acid and peptides.

Depending on skin type, formulations may include:

  • Azelaic acid (3–20%) to reduce melanin synthesis and prevent post-inflammatory pigmentation [6].
  • Niacinamide (2–4%) to strengthen the skin barrier and reduce redness [7].
  • Tretinoin (0.025–0.1%) to enhance gentle skin renewal and improve texture [8].

A 2024 study showed that 15% azelaic acid gel effectively treated post-inflammatory hyperpigmentation [6]. Niacinamide aids recovery by supporting the barrier function, while tretinoin promotes regeneration and smoother results over time.

Monderma offers a free online consultation for UK residents aged 16 and above. Each formulation is reviewed by a prescriber to ensure safety and suitability during the recovery process.

Conclusion

Fibrous papules, most often seen on the nose, are harmless lesions typically removed for cosmetic reasons. Understanding their characteristics and available treatments such as excision, cryotherapy, laser therapy, or electrocautery allows informed decisions about care.

Consulting a dermatologist can ensure accurate diagnosis and optimal results. Following treatment, Monderma’s personalised skincare can support healing, helping to maintain smooth and even skin tone with minimal scarring or pigmentation.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. Oakley A. Fibrous Papule of the Nose. DermNet. Published October 26, 2023.
  2. Pack S, Turner ML, Zhuang Z, et al. Cutaneous Tumors in Patients with Multiple Endocrine Neoplasia Type 1. J Clin Endocrinol Metab. 1998;83(3):1007–1011.
  3. Typology. Fibrous Papule: How to Eliminate It? Published October 23, 2024.
  4. Boixeda P, Sanchez-Miralles E, Azana JM, et al. Laser Treatment of Angiofibromas. J Dermatol Surg Oncol. 1994;20(12):808–812.
  5. NHS. Skin Cancer (Non-Melanoma). NHS Inform UK. Updated October 2024.
  6. Shucheng H, Zhou X, Du D, et al. Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Hyperpigmentation. Dermatol Ther (Heidelb). 2024;14(5):1293–1314.
  7. WBCL. Barrier Repair Reinvented: How Liposomal Niacinamide Calms and Strengthens Sensitive Skin. Published June 12, 2025.
  8. Govender K. The Use of Tretinoin Cream in the Management of Scars. Published March 12, 2025.
  9. Damman J, Biswas A. Fibrous Papule: A Histopathologic Review. J Cutan Pathol. 2018;45(11):803–810.
Categories
Miscellaneous

The Best Foods To Eat For Clear Skin

Your skin reflects your internal health, and what you eat has a measurable effect on its clarity, elasticity, and tone. A balanced diet for clear skin helps reduce inflammation, supports collagen production, and protects against oxidative stress.

This article explores evidence-based foods that promote healthy skin and identifies those that may contribute to acne and dullness.

Why Diet Shapes Skin Health

Nutrition And Skin Function

A nutritious diet provides the vitamins, minerals, and fatty acids that repair and protect the skin barrier. Poor diets high in refined sugars or fats may trigger inflammation or premature ageing. A 2020 JAMA Dermatology study involving 24,452 adults linked diets rich in fatty and sugary foods to a higher incidence of adult acne [1].

Antioxidant-rich fruits and vegetables help defend against free radicals and environmental stressors. They also supply key nutrients for hydration and repair, supporting a clear complexion.

Diet And Skin Myths

For decades, diet was dismissed as irrelevant to acne, partly due to the 1969 JAMA study claiming no chocolate link [3]. Later reviews found its design flawed [2]. Modern research now supports associations between dairy, sugar, and acne, confirming that food choices directly influence skin health [1,10,17].

Best Foods For Radiant Skin

Fatty Fish

Salmon, mackerel, and sardines provide omega-3 fatty acids that keep the skin barrier strong and hydrated. These fats may help reduce redness and support smoother texture [4].

Studies suggest omega-3s can ease inflammation and support elasticity while potentially offering mild protection from UV damage [16].

Avocados

Avocados contain vitamins E and C, which help neutralise free radicals and support collagen production. A 2022 Journal of Cosmetic Dermatology study found that daily avocado intake improved skin elasticity over eight weeks [5]. Their healthy fats also aid cell renewal and repair.

Nuts And Seeds

Almonds, walnuts, chia seeds, and sunflower seeds are rich in antioxidants, vitamin E, and zinc. These nutrients support healing and may protect against oxidative damage [6]. Walnuts also contain polyphenols that help defend against environmental stress.

Sweet Potatoes

Sweet potatoes are a source of beta-carotene, a vitamin A precursor that helps protect the skin from UV-related stress [7]. This antioxidant promotes vibrancy and smoother tone, supporting the immune system and overall skin balance.

Green Tea

Green tea is high in catechins, which have anti-inflammatory and antioxidant properties. Studies show that green tea extracts may reduce acne lesions and improve skin elasticity [8]. Regular consumption helps reduce redness and irritation.

Berries

Berries such as blueberries, strawberries, and raspberries contain vitamin C and flavonoids that support collagen and fight free radicals [9]. They are among the most antioxidant-rich foods, helping maintain firmness and a healthy glow.

FoodBenefit Summary
Fatty FishOmega-3s reduce inflammation, support hydration, and may protect against UV damage [4,7].
AvocadosVitamins E and C boost elasticity and aid collagen production [5].
Nuts And SeedsProvide antioxidants, zinc, and omega-3s for repair and protection [6].
Sweet PotatoesBeta-carotene promotes even tone and helps defend against UV stress [7].
Green TeaCatechins soothe inflammation and support clear skin [8].
BerriesVitamin C and flavonoids enhance radiance and reduce oxidative damage [9,11].

Table 1: Skin-enhancing foods and their key benefits

Worst Foods For Your Skin

Sugary Foods

Refined sugars in sweets, pastries, and soft drinks accelerate glycation, which weakens collagen and elasticity [11]. Spikes in blood sugar can increase inflammation, worsening acne and redness.

Dairy Products

A 2005 J Am Acad Dermatol study found an association between milk intake and acne in women [10]. Hormonal components in dairy may stimulate oil glands and increase breakouts. Limiting dairy intake can support clearer skin.

Processed Foods

Fast foods, fried snacks, and processed meats contain trans fats and additives that contribute to inflammation [11]. These foods offer few beneficial nutrients for the skin and may delay recovery from acne or irritation.

Alcohol

Alcohol reduces hydration and affects the body’s ability to retain moisture. Over time, excessive consumption may contribute to dullness and fine lines [11]. Keeping intake moderate helps preserve skin vitality.

Salty Snacks

Chips and salted nuts contain high levels of sodium that cause puffiness and dryness [15]. Switching to unsalted or low-sodium versions helps maintain balanced hydration.

FoodEffectExamples
SugarWeakens collagen and dulls skin [11].Cakes, sodas, pastries
DairyMay increase oil production and acne [10].Milk, cheese, yoghurt
Processed FoodsPromote inflammation and uneven tone [11].Fast food, crisps, sausages
AlcoholDehydrates and accelerates ageing [11].Wine, spirits, beer
Salty SnacksCause puffiness and dryness [15].Chips, pretzels, salted nuts

Table 2: Foods that may negatively affect skin health

Avoiding these foods supports healthier, more balanced skin while enhancing the benefits of nutrient-rich options.

Special Diets And Skin Outcomes

Carnivore Diet

A meat-only diet may temporarily reduce inflammation due to high protein and fat intake, but it lacks essential antioxidants and vitamin C [12]. Over time, this deficiency can lead to dryness and delayed healing unless supplemented.

Ketogenic Diet

The ketogenic diet promotes stable oil production but may trigger prurigo pigmentosa, also known as keto rash [13]. Maintaining adequate micronutrients and reintroducing some carbohydrates can reduce this risk.

Dr Rajani Katta from Baylor College of Medicine highlights that whole, unprocessed foods remain the most reliable way to nourish skin [14]. The NHS and British Dietetic Association also recommend varied diets rich in fruits and vegetables for long-term skin health [14,15].

Practical Tips For Skin-Friendly Eating

  • Drink about 2 litres of water daily for hydration.
  • Eat oily fish twice weekly for omega-3 fatty acids [4].
  • Limit processed and high-sugar foods.
  • Add berries and leafy vegetables daily for antioxidants.
  • Use olive oil instead of seed oils to support elasticity [18].
  • Choose unsalted nuts over crisps to reduce sodium intake.
  • Seek professional dietary or skincare advice if needed.

Conclusion

A balanced diet rich in fatty fish, avocados, nuts, and colourful vegetables supports clear, youthful skin by reducing inflammation and improving elasticity. Limiting processed, sugary, and dairy-heavy foods helps prevent breakouts and dryness.

Combining smart nutrition with consistent skincare forms a strong foundation for healthy, radiant skin. For further support, you can explore Monderma’s free skincare consultation.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. Penso L, et al. Association Between Adult Acne and Dietary Behaviors. JAMA Dermatology, 2020.
  2. Acne.org. Chocolate and Acne: Emerging Evidence. Updated 2024.
  3. Fulton JE Jr, Plewig G, Kligman AM. Effect of Chocolate on Acne Vulgaris. JAMA. 1969;210(11):2071–4.
  4. Calder PC. Omega-3 Fatty Acids and Inflammatory Processes. Nutrients, 2010.
  5. Henning SM, et al. Avocado Consumption Increased Skin Elasticity and Firmness in Women. J Cosmet Dermatol, 2022.
  6. Fan N, et al. Antioxidant and Anti-Inflammatory Properties of Walnut Constituents. Nutrients, 2023.
  7. Stahl W, Sies H. β-Carotene and Other Carotenoids in Protection from Sunlight. Am J Clin Nutr, 2012.
  8. Kim S, et al. The Effects of Green Tea on Acne Vulgaris. J Dermatol Treat, 2021.
  9. Min M, et al. The Influence of a Plant-Based Diet on Skin Health. Biomedicines, 2024.
  10. Adebamowo CA, et al. High School Dietary Dairy Intake and Teenage Acne. J Am Acad Dermatol, 2005.
  11. Cao C, et al. Diet and Skin Ageing – From the Perspective of Food Nutrition. Nutrients, 2020.
  12. British Dietetic Association. Skin Health. 2025.
  13. Xiao A, et al. Ketogenic Diet-Induced Prurigo Pigmentosa. Cureus, 2021.
  14. Katta R. Diet and Dermatology. J Clin Aesthet Dermatol, 2014.
  15. NHS. Eating a Balanced Diet. 2023.
  16. Pilkington SM, et al. Omega-3 Polyunsaturated Fatty Acids: Photoprotective Macronutrients. Exp Dermatol, 2011.
  17. Ryguła I, Pikiewicz W, Kaminiów K. Impact of Diet and Nutrition in Acne. Nutrients, 2024.
  18. Viola P, Viola M. Virgin Olive Oil as a Nutritional Skin Protector. Clin Dermatol, 2009.
Categories
Ingredients

Topical & Oral Ivermectin For Skin Health

Ivermectin is widely recognised for managing parasitic infections and dermatological conditions such as rosacea, scabies, and head lice [1,4].

This article reviews clinical findings, historical developments, and its role in modern skincare and parasitic disease control. All information presented is for educational purposes and should not replace medical advice.

What Is Ivermectin?

Discovered in 1975 by Satoshi Ōmura and William C. Campbell, ivermectin originates from Streptomyces avermitilis, a soil bacterium [1]. Initially used against river blindness (onchocerciasis), it has since become one of the most important antiparasitic medicines globally.

Available as oral tablets and topical cream, ivermectin is prescribed for both systemic and skin-related conditions, including rosacea and scabies [4,5].

Discovery & Global Impact

In the late 1970s, researchers refined avermectin into ivermectin, a safer, more effective antiparasitic agent [1]. Over 3.7 billion doses have since been distributed worldwide, significantly reducing parasitic infections in many regions [2].

Its success in public health paved the way for dermatological formulations, notably topical ivermectin 1% cream.

How Ivermectin Works

Ivermectin binds to glutamate-gated chloride channels in parasites, causing paralysis and death [3]. In skin applications, it also reduces inflammation by decreasing proinflammatory cytokines and eliminating Demodex mites, common in rosacea [4,5]. Dermatologist Dr Linda Stein Gold describes it as “a dual-action treatment that targets both inflammation and mites” [5].

Forms Of Ivermectin

FormPrimary UseTypical Strength
Oral Ivermectin TabletsSystemic infections & scabies150–200 µg/kg by weight [12]
Topical Ivermectin CreamRosacea & skin infestations1% formulation [4,5,13,14]

Table 1: Forms of ivermectin and their typical uses

Your healthcare professional will determine the best form depending on your condition, skin type, and treatment history.

Applications Of Topical Ivermectin

Rosacea Management

Rosacea causes facial redness and bumps often linked to Demodex mites [4,5,13,14]. Topical ivermectin helps control mites and inflammation, typically improving symptoms within 4–6 weeks.

A 2015 trial involving 1,378 participants reported significant reductions in inflammatory lesions after 12 weeks [5]. Another study found ivermectin reduced lesions by 83% compared with 73.7% for metronidazole [9].

Head Lice Treatment

Topical ivermectin lotion effectively eliminates head lice and their eggs. A 2012 NEJM study of 397 participants showed a 95.2% success rate at day 15 after a single use [6]. This formulation does not require combing and is easy to apply.

Scabies Control

Scabies mites burrow into skin, causing itching and irritation. Oral ivermectin is highly effective, achieving 68–92% cure rates with one or two doses [8]. Topical ivermectin may also help, but available data remain more limited [7].

Clinical Evidence

Robust trials confirm ivermectin’s efficacy for rosacea, lice, and scabies [4–7,13,14].

  • Rosacea: 83% lesion reduction compared with 73.7% for metronidazole [9].
  • Scabies: 2021 British Journal of Dermatology review supports ivermectin’s use in resistant cases [7].
  • Lice: 0.5% lotion achieved up to 95% lice clearance after one application [6].

Practical Tips For Topical Use

ConditionFrequencyTime To ResultsTip
RosaceaDaily4–6 weeksUse pea-sized amount on clean, dry skin.
Scabies1–2 doses48 hoursApply evenly across body; follow medical guidance.
Head LiceOnce1–2 daysAvoid conditioners before application.

Table 2: Practical tips for topical ivermectin use

Consistency is key for best results. Consult your healthcare provider if irritation or allergic reactions occur.

Ivermectin Safety & Side Effects

Topical and oral ivermectin are generally well tolerated. Adverse effects occur in fewer than 1–2% of users [10]. Reported side effects include mild redness or itching at the application site.

Because ivermectin does not easily cross the blood–brain barrier, neurological side effects are extremely rare [11,12]. Those pregnant or breastfeeding should consult a healthcare professional, as safety data remain limited [2].

Oral vs Topical Ivermectin

  • Oral ivermectin is suited for systemic or widespread infections and scabies.
  • Topical ivermectin targets localised skin conditions like rosacea or lice infestations.

Your healthcare provider can determine which form best fits your needs and check for potential interactions with other medications [12].

Key Benefits

  • Demonstrated efficacy for rosacea, lice, and scabies [4–7].
  • Usually well tolerated with mild, transient effects.
  • Affordable and accessible globally.
  • Available in both oral and topical forms for tailored treatment.

Caution is advised during pregnancy, as current research shows insufficient safety data [2].

Conclusion

Ivermectin, in both topical and oral forms, remains a well-researched option for managing certain parasitic and inflammatory skin conditions. Evidence supports its effectiveness for rosacea, scabies, and head lice, with minimal reported side effects. Consult a healthcare professional before starting treatment to ensure suitability.

For personalised skincare advice or topical prescription formulations, consider Monderma’s free consultation.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. The Nobel Assembly at Karolinska Institutet. The 2015 Nobel Prize in Physiology or Medicine – Press Release. 2015.
  2. Nicolas P, Maia MF, Bassat Q, et al. Safety of oral ivermectin during pregnancy: a systematic review and meta-analysis. The Lancet Global Health, 2020.
  3. Wolstenholme AJ. Glutamate-gated Chloride Channels. Journal of Biological Chemistry, 2012.
  4. NICE. Inflammatory lesions of papulopustular rosacea: ivermectin 10 mg/g cream. Evidence Summary ESNM68, 2016.
  5. Stein Gold L, Kircik L, Fowler J, et al. Ivermectin 1% cream for inflammatory lesions of rosacea. J Am Acad Dermatol, 2015.
  6. Pariser DM, Meinking TL, Bell M, et al. Topical 0.5% ivermectin lotion for treatment of head lice. N Engl J Med, 2012.
  7. NICE. Scabies: ivermectin. Clinical Knowledge Summaries, 2021.
  8. Chouela E, Abeldaño A, Pellerano G, et al. Equivalent therapeutic efficacy and safety of ivermectin and lindane in human scabies. Arch Dermatol, 1999.
  9. Taieb A, Ortonne JP, Ruzicka T, et al. Superiority of ivermectin 1% cream over metronidazole 0.75% in treating rosacea. Br J Dermatol, 2015.
  10. Campillo JT, Boussinesq M, Bertout S, et al. Serious adverse reactions associated with ivermectin: a pharmacovigilance study. PLoS Negl Trop Dis, 2021;15(4):e0009354.
  11. Guzzo CA, Furtek CI, Porras AG, et al. Safety, tolerability, and pharmacokinetics of escalating doses of ivermectin. J Clin Pharmacol, 2002.
  12. Merck & Co. Stromectol (ivermectin) prescribing information. 2009.
  13. Walker S, Cassia A, Lanza M, et al. Efficacy and safety of topical ivermectin for rosacea: a systematic review. Br J Dermatol, 2021.
  14. Gether L, Overgaard LK, Egeberg A, Thyssen JP. Topical ivermectin for papulopustular rosacea: review of clinical evidence. Dermatol Ther, 2018;8(3):379–387.
Categories
Treatments

Hyperpigmentation Skincare Ingredients For A More Even Skin Tone

Hyperpigmentation affects people across all skin tones, often presenting as melasma, sunspots, or post-inflammatory marks. These dark patches can make skin appear uneven and dull. Evidence-based skincare ingredients help to fade discolouration safely and effectively when used consistently.

This article reviews proven ingredients for hyperpigmentation and how tailored formulations, such as Monderma’s prescription blends, may support a more even skin tone.

Understanding Hyperpigmentation

What Causes Hyperpigmentation

Hyperpigmentation occurs when excess melanin, responsible for skin colour, is produced by melanocytes. Triggers include sun exposure, hormonal fluctuations, and inflammation from acne or injury. According to the NHS, UV radiation stimulates melanin production, worsening sun-induced pigmentation [1]. StatPearls reports that hormonal melasma affects up to 50% of pregnant women [2].

Identifying The Type Of Pigmentation

Different forms of hyperpigmentation require tailored care:

  • Melasma: Hormonal pigmentation often on cheeks or forehead.
  • Sunspots: Caused by long-term UV exposure.
  • Post-Inflammatory Hyperpigmentation (PIH): Dark marks following acne or irritation.

Understanding the cause helps match the right skincare ingredients for optimal results.

Key Ingredients In Hyperpigmentation Creams

Vitamin C

Vitamin C (ascorbic acid) inhibits tyrosinase, reducing melanin formation and promoting brightness. A 2013 study confirmed that regular vitamin C use visibly lightens dark patches [3]. It also supports photoprotection when combined with sunscreen.

Tretinoin

Tretinoin accelerates skin cell turnover, helping shed pigmented cells. JAMA Dermatology found that 0.05% tretinoin can reduce melasma severity by about 40% after 24 weeks [4]. Because tretinoin may cause mild irritation initially, gradual use is recommended.

Niacinamide

Niacinamide (vitamin B3) reduces melanin transfer and supports the skin barrier. Clinical studies show that 4% niacinamide can decrease dark patches by up to 30% in eight weeks [5]. It is suitable for sensitive skin and enhances tolerance to other active ingredients.

Azelaic Acid

Azelaic acid, derived from grains, helps reduce pigmentation and inflammation. NICE notes that a 20% strength may be effective for hyperpigmentation management [6]. It is gentle and can be used on sensitive or acne-prone skin.

Alpha Arbutin

Alpha arbutin inhibits melanin production without significant irritation [7]. It is suitable for daily use and can complement other brightening agents.

Kojic Acid

Kojic acid suppresses tyrosinase activity, lightening dark spots. Studies confirm its effectiveness in improving uneven tone when used consistently [8].

Adapalene

Adapalene, a synthetic retinoid, promotes cell renewal and helps fade post-inflammatory pigmentation. StatPearls reports 0.1% adapalene reduces PIH within 12 weeks [2].

Hydroquinone

Hydroquinone remains one of the most potent topical depigmenting agents. Studies in JAMA Dermatology show 4% hydroquinone can lighten melasma in eight weeks [4]. Because of its strength, medical supervision is advised for safe use.

How Monderma’s Custom Formula Supports Hyperpigmentation Care

Monderma provides individually compounded hyperpigmentation creams containing clinically supported actives such as tretinoin, azelaic acid, adapalene, and hydroquinone.

Consultations are free and reviewed by registered healthcare professionals to ensure safety and suitability. This aligns with NICE guidance recommending individualised treatment plans [6]. Combining ingredients can improve outcomes compared with single agents [9].

Key Ingredients In Monderma Formulations

IngredientWhat It IsHow It May Help
AdapaleneSynthetic retinoidBoosts turnover & evens tone [2].
Azelaic AcidNaturally derived acidReduces pigmentation & inflammation [6].
HydroquinoneLightening agentLowers melanin for stubborn patches [4].
NiacinamideVitamin B3Limits pigment transfer & soothes [5].
TretinoinVitamin A derivativeSpeeds renewal & fades uneven tone [4].

Table 1: Key ingredients in Monderma formulations

Sunscreen For Hyperpigmentation: Essential Protection

Daily sun protection is crucial for preventing and managing pigmentation. The NHS recommends using a broad-spectrum SPF 30 or higher [1]. For individuals prone to hyperpigmentation, SPF 50 offers additional protection. Sunscreen helps prevent recurrence and maximises the effects of topical treatments.

Choosing The Right Hyperpigmentation Products

Match Your Skin Type

Oily skin may respond well to niacinamide or adapalene. Sensitive skin may prefer azelaic acid or lower retinoid concentrations.

Test New Products

A 24-hour patch test helps identify possible reactions. Discontinue use if redness or irritation develops.

Seek Professional Guidance

Consulting a licensed prescriber or dermatologist ensures appropriate ingredient selection. Monderma’s healthcare team follows clinical guidance from sources such as UpToDate and NICE [6][7].

Enhancing Your Routine With Retinol For Hyperpigmentation

Retinol, a gentler derivative of vitamin A, offers a milder option for those unable to tolerate tretinoin. Regular use promotes smoother texture and reduced discolouration. Combining retinol or tretinoin with daily SPF enhances overall results and reduces risk of irritation.

Conclusion

Hyperpigmentation can be improved through evidence-based skincare ingredients such as tretinoin, hydroquinone, niacinamide, azelaic acid, and vitamin C. Combining these actives under professional supervision supports more even tone and healthier-looking skin. Consistent use of SPF 50 sunscreen is essential to prevent recurrence.

Those seeking tailored formulations can complete your free Monderma consultation to receive prescription-strength options guided by healthcare professionals.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. NHS. Sunscreen and sun safety. NHS, accessed 11 July 2025.
  2. Postinflammatory Hyperpigmentation. StatPearls, updated 2023.
  3. Telang, P.S. Vitamin C in dermatology. Indian Dermatology Online Journal, 2013; 4(2):143–146.
  4. Kang, W.H. et al. Intermittent therapy for melasma in Asian patients with combined topical agents. J Dermatol. 1998;25(9):587–596.
  5. Hakozaki, T. et al. The effect of niacinamide on reducing cutaneous pigmentation. Br J Dermatol. 2002;147(1):20–31.
  6. Scenario: Management of acne vulgaris in primary care. NICE Clinical Knowledge Summaries, 2019.
  7. Hyperpigmentation disorders: Treatment and management. UpToDate, 2024.
  8. Lim, J.T. Treatment of Melasma Using Kojic Acid in a Gel Containing Hydroquinone and Glycolic Acid. Dermatol Surg. 1999;25(4):282–284.
  9. Bandyopadhyay, D. Topical treatment of melasma. Indian J Dermatol. 2009;54(4):303–309.
Categories
Miscellaneous

NHS Vs Private: The Problems Facing The NHS

The National Health Service (NHS) remains the cornerstone of healthcare in the UK, providing treatment based on need rather than income. Since its creation in 1948, the NHS has been a symbol of universal care. However, it faces growing challenges including funding shortages, staff vacancies, and ageing infrastructure. These ongoing pressures have led many people to explore private healthcare for faster or more personalised access.

This article examines the main problems facing the NHS, compares NHS and private healthcare, and highlights potential long-term solutions including how innovative private services, such as Monderma’s personalised skincare, support accessibility.

Current Problems & Pressures Facing The NHS

Funding Constraints

The NHS continues to face financial pressure as demand rises faster than available resources. In 2022–23, its total budget reached £153 billion, but growing demand and operational costs have created shortfalls [a].

In mid-2024, over 7.6 million people in England were on hospital waiting lists [b]. Limited funds restrict staff recruitment, facility upgrades, and service expansion. These pressures have required prioritisation of urgent cases and created extended waiting times for elective procedures.

Staffing Shortages

Staffing shortages remain one of the most pressing NHS challenges. In 2023, there were approximately 121,000 vacancies across clinical and non-clinical roles, representing a vacancy rate of 8.4% [c].

This strain leads to longer working hours, burnout, and higher staff turnover. Retaining and training staff through competitive pay, improved working environments, and career progression opportunities are vital steps to improve workforce stability.

Ageing Infrastructure

More than one-third of NHS hospitals operate in buildings over 50 years old [d]. Outdated facilities reduce efficiency and struggle to accommodate modern technologies. Refurbishing and rebuilding hospitals requires major investment, but these projects often compete with the need to maintain day-to-day services.

Administrative Complexities

The NHS’s scale and administrative layers can slow processes. Bureaucracy and manual systems increase delays in patient flow and resource use. Increasing digital transformation through integrated data systems and automation may improve patient management and staff efficiency.

NHS Vs Private: Comparing Key Differences

FactorNHSPrivate Healthcare
AccessibilityFree at the point of use but may involve waiting timesPaid service offering faster access
Waiting Times7.6 million people waiting for treatment in 2024 [b]Appointments available sooner
Quality of CareComprehensive services under one systemModern facilities and choice of specialists
CostFunded by taxationFunded by private insurance or self-payment
FlexibilityLimited by resourcesPatients choose specialists and timing

Table 1: Overview of NHS vs private healthcare

Personalised Skincare & Private Sector Innovation

Private care providers have introduced more digital, patient-focused models that complement NHS services. Monderma, a UK-based provider, offers prescription skincare tailored to concerns such as acne, ageing skin, hyperpigmentation, and rosacea.

After completing a free online consultation, GPhC-registered prescribers review suitability and create personalised formulas containing dermatological actives such as tretinoin, niacinamide, or azelaic acid in a vegan base [e].

This model demonstrates how private digital healthcare can reduce waiting times and improve access while supporting patients who may face long NHS dermatology waits. Monderma’s approach aims to complement, not replace NHS dermatological care.

Long-Term Solutions For NHS Sustainability

Increased Investment

The Institute for Fiscal Studies reports that NHS funding needs to grow by 3–3.5% per year in real terms to keep pace with demand [f]. Funding should target staffing, facility modernisation, and preventive care to reduce pressure on hospitals.

Recruitment & Retention

The NHS Long Term Workforce Plan (2023) aims to expand training places by 30% by 2030 [g]. Improving pay structures, staff wellbeing, and flexible working arrangements can support retention and reduce burnout.

Embracing Technology

Digital health tools such as telemedicine and electronic health records can increase efficiency and reduce administrative workloads. By 2023, around 90% of NHS trusts had implemented digital patient records [h]. Ongoing digital transformation remains a central pillar of modernisation.

Public-Private Partnerships

Collaborations between public and private sectors can help reduce waiting lists and share best practices. Such partnerships must remain transparent and prioritise public benefit, ensuring care quality across all providers [i].

Choosing Between NHS & Private Healthcare

Choosing between NHS and private healthcare depends on personal needs, urgency, and financial capacity. The NHS guarantees access to essential treatment for all, while private care offers flexibility and shorter waiting times.

Private healthcare options, including Monderma’s tailored prescription skincare, can complement NHS services for non-urgent conditions by providing accessible and efficient care. To explore whether a personalised approach could support your skincare goals, complete a free online consultation today.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. NHS England. (2023). NHS budget allocation 2022–23.
  2. NHS Confederation. (2024). Key statistics on the NHS.
  3. The King’s Fund. (2023). NHS workforce vacancies report.
  4. UK Parliament. (2024). Hospital building in England: Plans and progress.
  5. Monderma. (2024). Prescription skincare treatments.
  6. Institute for Fiscal Studies. (2023). NHS funding, resources and treatment volumes.
  7. NHS England. (2023). Long term workforce plan.
  8. UK Parliament Health and Social Care Committee. (2023). Digital transformation in the NHS.
  9. The Health Foundation. (2022). Health care funding.
Categories
Ingredients

Effects Of Adapalene On Acne Symptom Relief

Adapalene is a topical retinoid widely used to manage acne and improve overall skin texture. This vitamin A derivative helps support smoother, clearer skin through enhanced cell turnover and reduced inflammation. It is often recommended for individuals seeking targeted acne care with well-established clinical support.

This article examines adapalene’s evidence-based benefits, what to expect during use, and how to safely introduce it into a skincare routine.

What Is Adapalene & How It Works

Adapalene is a third-generation retinoid that regulates cell turnover and minimises inflammation, helping to manage acne-related symptoms. It is described in reviews as well tolerated and suitable for sensitive skin when used correctly [1].

How Adapalene Functions

Adapalene promotes healthy skin renewal by encouraging new cell growth while helping to prevent clogged pores. It also supports reduced redness and swelling linked to acne [1].

Comparing Retinol & Adapalene

Both adapalene and retinol are vitamin A derivatives but serve different purposes. Retinol is generally used for cosmetic ageing concerns, while adapalene is clinically indicated for acne.

IngredientWhat It IsProsCons
AdapaleneThird-generation retinoid (0.1% OTC, 0.3% prescription).Targets acne effectively, stable, gentler on skin.May cause mild dryness early on.
RetinolOver-the-counter vitamin A derivative.Helps with signs of ageing, less irritating.Less potent for acne, light-sensitive.
TretinoinPrescription-only first-generation retinoid.Highly effective for both acne and wrinkles.May cause irritation, less stable than adapalene.

Table 1: Comparing common retinoids by use, benefits, and tolerability

How Adapalene Targets Acne & Improves Skin

Adapalene works by boosting cell turnover and helping prevent blocked pores, a key factor in acne development. A 2021 review reported a significant reduction in acne lesions within 12 weeks of consistent use [2].

Clearing Pores & Smoother Texture

Adapalene helps clear pores, promoting smoother skin over time. Studies report a reduction in mild acne spots by up to 47% in three months [5].

Calming Inflammation

Its anti-inflammatory effects can help reduce redness and swelling associated with acne [1].

What To Expect When Starting Adapalene

Mild irritation or dryness may appear during the first few weeks. These effects typically resolve as the skin adjusts. Dermatologists recommend starting with adapalene 0.1% every other night and using a gentle moisturiser to improve comfort [4].

Adjustment Period

Temporary redness or peeling can occur in the first month. These symptoms generally settle with continued, consistent use [8].

How To Build A Routine With Adapalene

  1. Cleanse: Use a gentle, non-foaming cleanser.
  2. Apply Adapalene: A pea-sized amount for the entire face.
  3. Moisturise: Use fragrance-free, non-comedogenic moisturiser.
  4. Sun Protection: Apply SPF 30+ daily.

After 2–4 weeks, increase to nightly use if tolerated [4].

TipActionBenefit
Start SlowApply every other nightReduces irritation
MoisturiseUse gentle moisturiser after adapaleneImproves comfort
Use SPFApply daily sunscreenProtects against sensitivity
Stay ConsistentUse for 8–12 weeksImproves long-term results
Add HydrationCombine with hyaluronic acidMaintains skin balance

Table 2: Practical guidance for using adapalene safely and effectively

Adapalene In The UK

In the UK, adapalene 0.1% is available over the counter, while 0.3% requires a prescription. Healthcare professionals can help assess suitability based on skin type and acne severity [1].

Choosing Between Cream & Gel

  • Creams: Best for dry or sensitive skin, as they add hydration.
  • Gels: Suit oily skin and absorb quickly with a matte finish.

Managing Side Effects

Common side effects include mild dryness, redness, or peeling in early use. These usually improve with moisturising and gentle cleansing [4]. Avoid combining adapalene with exfoliating acids during the initial phase to prevent irritation.

Long-Term Use & Skin Health

Regular use of adapalene can support clearer skin and smoother texture over time. Its role in long-term acne management is well established in clinical literature [1,2].

Before starting treatment, review your skin type and medical history with a healthcare professional. Consistent use and correct application maximise results while maintaining skin comfort.

Conclusion

Adapalene is a well-studied topical retinoid used to manage acne and improve skin texture. It enhances cell turnover, helps prevent clogged pores, and supports balanced, healthier skin.

Starting slowly and maintaining hydration ensures optimal comfort and effectiveness. For personalised prescription skincare, explore a free consultation with Monderma to see if adapalene suits your skin’s needs.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. Piskin, S., & Uzunali, E. (2007). A review of the use of adapalene for the treatment of acne vulgaris. Clinical, Cosmetic and Investigational Dermatology, 1, 129–134.
  2. Stuart, B., et al. (2021). Topical preparations for the treatment of mild-to-moderate acne vulgaris: systematic review and network meta-analysis. British Journal of Dermatology, 185(3), 512–525.
  3. Loss, M. J., et al. (2018). Adapalene 0.3% Gel Shows Efficacy for the Treatment of Atrophic Acne Scars. Dermatology and Therapy, 8(2), 245–257.
  4. Dosik, J. S., Homer, K., & Arsonnaud, S. (2005). Cumulative Irritation Potential of Adapalene 0.1% Cream and Gel Compared With Tretinoin Microsphere 0.04% and 0.1%. Cutis, 75(4), 238–243.
  5. Thiboutot, D., et al. (2006). Adapalene gel 0.3% for the treatment of acne vulgaris. Journal of the American Academy of Dermatology, 54(2), 242–250.
  6. Stein Gold, L., et al. (2016). Efficacy and Safety of Adapalene 0.3%/Benzoyl Peroxide 2.5% Gel in Moderate and Severe Acne. American Journal of Clinical Dermatology, 17(6), 595–604.
  7. Thielitz, A., Sidou, F., & Gollnick, H. (2007). Control of microcomedone formation with adapalene gel 0.1%. Journal of the European Academy of Dermatology and Venereology, 21(6), 747-753.
  8. Dunlap, F. E., et al. (1998). Adapalene 0.1% gel for acne vulgaris: superiority in tolerance and preference. British Journal of Dermatology, 139(Suppl 52), 17–22.
  9. Tan, J., et al. (2018). Fixed combination regimens of adapalene 0.1%/benzoyl peroxide 2.5% gel in acne vulgaris. European Journal of Dermatology, 28(4), 502–508.
  10. Khemani, U. N., Sharma, S., & Mehta, R. M. (2016). Clinical efficacy and safety of adapalene gel (0.1%) and tretinoin cream (0.025%) in acne. International Journal of Basic & Clinical Pharmacology, 5(3), 628–634.
Categories
Treatments

Exploring Papules & Skin Conditions Behind Them

Papules are small, raised bumps that appear in many common skin conditions. Though they can look concerning, most are harmless. These tiny lesions can vary in colour and texture, appearing anywhere on the body. Understanding what causes papules helps determine if they are temporary irritations or signs of something requiring medical attention.

This article explores papules, how they form, conditions that cause them, and the differences between papules, moles, and warts.

What Are Papules

Papules are small, solid skin bumps under 1 cm in diameter [1,2]. They contain no pus or fluid, unlike pustules or vesicles [3]. Papules can appear as red, brown, purple, or flesh-toned, and may have a smooth or rough surface [3].

Recognising their appearance helps distinguish them from other skin lesions and supports early identification of potential causes.

How Papules Form

Papules develop from irritation or inflammation that causes localised swelling of the skin [4]. This occurs when the immune system reacts to internal or external triggers such as infections, allergies, or chronic skin conditions [5].

Common Triggers Include

  • Blocked pores or bacterial infection
  • Skin irritation from harsh skincare products
  • Sun exposure or environmental pollutants
  • Hormonal changes or high stress levels [6]

Identifying these triggers supports prevention and helps guide gentle, evidence-based care.

Common Skin Conditions & Papules

Papules are common in several dermatological conditions. Each condition presents differently and may require specific management approaches.

Skin ConditionCharacteristicsCommon LocationsManagement Strategies
AcneInflamed bumps caused by clogged pores that may progress to pustules or nodules [7].Face, back, shouldersTopical benzoyl peroxide or retinoids; skincare adjustments; lifestyle changes [8].
EczemaDry, itchy skin with red papules during flare-ups [9].Elbows, knees, faceUse emollients, mild corticosteroids, and avoid triggers [10].
PsoriasisRed, scaly papules merging into plaques due to immune activation [11].Elbows, knees, scalpApply topical agents, phototherapy, or prescribed systemic treatments [12].
Lichen PlanusPurple, itchy, flat-topped papules that may appear in clusters [13].Wrists, ankles, mouthTopical corticosteroids, antihistamines, or light therapy [14].

Table 1: Common skin conditions associated with papules and their management

Differentiating Papules From Other Skin Lesions

Papules can resemble other lesions such as moles, warts, or nodules. Recognising their differences helps guide accurate assessment and care.

Lesion TypeCharacteristicsCauseTreatment
MolesPigmented, stable skin growths that can change with time; sudden changes may require review [15].MelanocytesRegular monitoring or excision if clinically necessary [16].
WartsRough, raised bumps with a cauliflower-like surface; spread through HPV [17].Viral infectionTopical wart treatments or cryotherapy under supervision [18].
NodulesLarger, deeper, solid lumps beneath the skin’s surface [19].Varies by conditionDermatologist assessment; sometimes medication or surgery [20].

Table 2: Differences between papules and other common skin lesions

When To Seek Medical Advice

Most papules heal naturally, but medical advice may be needed if:

  • They rapidly change in size, shape, or colour [16].
  • They become painful, itchy, or inflamed [5].
  • Other symptoms such as fever or fatigue appear [4].

Early professional assessment can help rule out infection or more serious conditions [21].

Treatment Options

Treatment depends on the underlying cause. Dermatologists or healthcare professionals can recommend suitable care.

Topical Treatments

Mild acne-related papules may respond to benzoyl peroxide or salicylic acid [8]. Prescription retinoids such as tretinoin may help reduce blocked pores and inflammation [22].

Moisturisers & Creams

For eczema or psoriasis, emollients and mild corticosteroids reduce dryness and irritation [10,12]. Azelaic acid can be used to help manage inflammation and redness associated with rosacea [23].

Medical Procedures

Stubborn lesions like warts may require dermatological treatments such as cryotherapy or laser therapy, performed safely by qualified professionals [18].

Monderma’s Role In Personalised Skincare

Monderma provides prescription skincare designed for acne, rosacea, hyperpigmentation, and other skin concerns. After a free online consultation, healthcare professionals formulate treatments using evidence-based ingredients such as azelaic acid, niacinamide, or tretinoin.

This personalised approach supports safe, effective management tailored to individual skin types. Learn more through Monderma’s free online consultation.

Conclusion

Papules are small, raised lesions that often result from inflammation or common skin conditions such as acne, eczema, or psoriasis. Most are harmless, but persistent or changing papules should be reviewed by a healthcare professional.

With professional support and tailored skincare, managing papules becomes more straightforward. Explore Monderma’s free consultation service to discover personalised options for clearer, balanced skin.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. Nast A, et al. Papule. In: ScienceDirect Topics. 2016.
  2. Habif TP. Clinical Dermatology. 6th ed. Elsevier; 2015.
  3. Marks JG, Miller JJ. Lookingbill and Marks’ Principles of Dermatology. 5th ed. Elsevier; 2013.
  4. Bolognia JL, et al. Dermatology. 4th ed. Elsevier; 2017.
  5. Goldsmith LA, et al. Fitzpatrick’s Dermatology in General Medicine. 8th ed. McGraw-Hill; 2012.
  6. Draelos ZD. Cosmetic Dermatology: Products and Procedures. Wiley-Blackwell; 2015.
  7. Zaenglein AL, et al. Guidelines of care for the management of acne vulgaris. J Am Acad Dermatol. 2016;74(5):945-973.
  8. NICE. Acne vulgaris: management. 2021.
  9. Eichenfield LF, et al. Guidelines of care for atopic dermatitis. J Am Acad Dermatol. 2014;70(2):338-351.
  10. NICE. Atopic eczema in under 12s: diagnosis and management. 2007.
  11. Menter A, et al. Guidelines of care for psoriasis and psoriatic arthritis. J Am Acad Dermatol. 2008;58(5):826-850.
  12. NICE. Psoriasis: assessment and management. 2012.
  13. Le Cleach L, Chosidow O. Lichen planus. N Engl J Med. 2012;366(8):723-732.
  14. American Academy of Dermatology. Lichen planus: Diagnosis and treatment. 2025.
  15. Bolognia JL, et al. Melanocytic nevi and neoplasms. In: Dermatology. 4th ed. Elsevier; 2017.
  16. UpToDate. Melanoma: Clinical features and diagnosis. 2023.
  17. Sterling JC, et al. British Association of Dermatologists’ guidelines for the management of cutaneous warts. Br J Dermatol. 2014;171(4):696-712.
  18. Sabry AO, Patel BC. Papillomas: A Multisystem Overview of HPV-Associated and HPV-Independent Lesions. StatPearls. 2023.
  19. DermNet NZ. Terminology in dermatology. 2025.
  20. American Academy of Dermatology. Find skin cancer: How to perform a skin self-exam. 2023.
  21. NHS. Itchy Skin. 2023.
  22. Leyden JJ, Stein-Gold L, Weiss J. Why topical retinoids are mainstay therapy for acne. Dermatol Ther (Heidelb). 2017;7(3):293–304.
  23. Thiboutot D, et al. Standard management options for rosacea. J Am Acad Dermatol. 2020;82(6):1501-1510.
Categories
Miscellaneous

Skincare For Sensitive Skin: Your Guide To Hydration

Dry and sensitive skin often feels tight, flaky, or irritated. Choosing the right skincare products for dry and sensitive skin is essential to restore comfort, hydration, and skin barrier strength.

This guide explains how to care for this skin type using dermatologically supported ingredients and practical steps. A consistent skincare routine for sensitive skin can improve hydration, reduce discomfort, and enhance overall resilience. Understanding which ingredients to use and which to avoid makes all the difference.

Understanding Dry & Sensitive Skin

Dry sensitive skin is characterised by reduced natural oils and increased reactivity to environmental stressors. This can lead to redness, flaking, and discomfort. Sensitive skin often overlaps with dry skin, and studies suggest a strong correlation between the two [1].

Maintaining the skin barrier is vital. When compromised, it allows moisture loss and irritant penetration, which causes inflammation and tightness. Selecting gentle, fragrance-free, and hydrating products helps repair and protect this barrier.

Key Ingredients To Look For

The best skincare products for sensitive skin combine moisture-retaining ingredients with soothing agents.

IngredientBenefit
Hyaluronic AcidHolds up to 1000 times its weight in water, providing deep hydration [2].
GlycerinAttracts moisture to the skin, supporting hydration and comfort [3].
CeramidesStrengthen the skin barrier and prevent water loss [3].
Aloe VeraCalms redness and soothes irritation [4].
Colloidal OatmealProtects, softens, and enhances moisturisers for sensitive skin [5].

Table 1: Key hydrating and soothing ingredients for sensitive skin

These ingredients form the foundation of effective skincare for dry and sensitive skin by hydrating, protecting, and reducing reactivity.

Best Skincare Routine For Dry Sensitive Skin

A gentle and consistent skincare routine helps manage dryness while supporting long-term hydration.

Step 1: Gentle Cleansing

Choose a fragrance-free cleanser with glycerin or ceramides. It removes impurities without stripping natural oils, supporting hydration and comfort [3].

Step 2: Hydrating Toner

Apply a mild, alcohol-free toner with rosewater or hyaluronic acid to refresh and prepare the skin for serums. It helps rebalance pH and increases moisture absorption [2].

Step 3: Nourishing Serum

Use a serum containing hyaluronic acid to replenish water levels. This step reinforces hydration for smoother, more supple skin [2].

Hyaluronic acid also features in Monderma’s personalised custom formulas for improving dryness and sensitivity.

Step 4: Moisturisation

Seal in moisture with a cream rich in ceramides and glycerin. These ingredients strengthen the skin barrier and prevent trans-epidermal water loss [3].

Step 5: Sun Protection

Finish your morning routine with a broad-spectrum, mineral-based SPF 30 or higher. Zinc oxide and titanium dioxide are gentle options suitable for sensitive skin [3].

Why Fragrance-Free Matters

Fragrance-free skincare is crucial for sensitive skin. Added scents, whether natural or synthetic, can trigger irritation, redness, and dryness. NHS dermatology guidance recommends avoiding fragrance in cleansers, serums, and moisturisers to reduce flare-ups and preserve hydration.

Additional Tips For Managing Dry Sensitive Skin

  • Patch Test New Products: Always test products on a small area before full use to ensure compatibility [6].
  • Avoid Hot Water: Use lukewarm water when cleansing to prevent further dryness [3].
  • Stay Hydrated: Drinking enough water supports skin moisture balance from within [3].
  • Use a Humidifier: Adding moisture to your environment helps relieve dryness, especially during colder months [3].

These simple steps can significantly improve comfort and hydration for sensitive skin.

Conclusion

The best skincare for sensitive skin focuses on hydration, gentle cleansing, and barrier support. Prioritise ingredients such as ceramides, glycerin, and hyaluronic acid, and avoid fragrance or harsh actives that may increase irritation.

For professional guidance, Monderma offers free online consultations with healthcare professionals who can tailor hydrating formulas to your skin’s needs. Explore your personalised options and share this guide to help others care for their sensitive skin.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. Duarte I, et al. Sensitive skin: review of an ascending concept. An Bras Dermatol. 2017;92(4):521–525.
  2. Pavicic T, et al. Efficacy of cream-based formulations of hyaluronic acid of different molecular weights in anti-wrinkle treatment. J Drugs Dermatol. 2011;10(9):990–1000.
  3. Lodén M. The clinical benefit of moisturizers. J Eur Acad Dermatol Venereol. 2005;19(6):672–688.
  4. Raw V. Is aloe vera good for your skin? Patient.info. 2024.
  5. Wartenberg L. What Is Colloidal Oatmeal? Benefits, Uses, and Safety. Healthline. 2020.
  6. NHS. Allergies: Diagnosis.
Categories
Ingredients

Azelaic Acid & Niacinamide Skin Benefits

Azelaic acid and niacinamide are key ingredients in modern dermatology, recognised for their versatility and suitability across multiple skin types. Used together, they improve skin tone, texture, and radiance with minimal irritation.

This article explores their evidence-based benefits and explains how to incorporate them safely into a skincare routine.

Understanding Azelaic Acid

Azelaic acid is a naturally occurring dicarboxylic acid derived from grains such as wheat and barley. It provides antimicrobial and anti-inflammatory activity, helping to reduce acne, soothe rosacea, and fade post-acne marks. Its mild nature makes it suitable for most skin types, including sensitive or acne-prone skin.

Benefits Of Azelaic Acid

Reduces Acne:
Azelaic acid inhibits Propionibacterium acnes and normalises keratin production, preventing clogged pores. In clinical trials, 20% azelaic acid cream reduced acne lesions by up to 65% over 12 weeks in mild-to-moderate acne [1].

Evens Skin Tone:
By blocking tyrosinase, azelaic acid reduces excess melanin that causes dark spots. A study comparing 20% azelaic acid with 4% hydroquinone showed similar effectiveness in lightening melasma over several months [2].

Soothes Redness:
In rosacea, 15% azelaic acid gel significantly decreased erythema and papules after 15 weeks of treatment [3].

The Power Of Niacinamide

Niacinamide (vitamin B3) is a water-soluble vitamin that enhances barrier strength and regulates sebum. It supports hydration, improves skin resilience, and complements actives such as azelaic acid.

Benefits Of Niacinamide

Boosts Hydration:
Niacinamide increases ceramide production, improving barrier function and reducing moisture loss. Studies show 4–5% concentrations improve hydration within weeks [4].

Reduces Redness:
By calming inflammation, niacinamide alleviates irritation and redness. In rosacea, 4% niacinamide moisturiser improved symptoms after several weeks [5].

Refines Texture & Pores:
Niacinamide regulates oil production, minimising enlarged pores and promoting smoother texture [4].

Supports Anti-Ageing:
It aids collagen synthesis, reducing fine lines and enhancing overall skin radiance [4].

Why Combine Azelaic Acid & Niacinamide

Together, these ingredients form a complementary duo: azelaic acid gently exfoliates and brightens, while niacinamide restores hydration and barrier integrity. This pairing suits acne-prone, sensitive, and hyperpigmented skin, offering results with minimal irritation.

Monderma’s dermatology team can design personalised formulations combining both actives, adjusted to each skin type following a free consultation.

How They Work Together

BenefitDescription
Enhanced BrighteningBoth ingredients target pigmentation; combined use may yield additive effects though direct clinical data are limited [6].
Improved TextureAzelaic acid’s exfoliation pairs with niacinamide’s barrier support to smooth and even skin tone.
Reduced IrritationTheir anti-inflammatory effects make the combination suitable for rosacea and sensitive skin [2,5].

Table 1: Combined benefits of azelaic acid and niacinamide

Formulation Considerations

Both actives are typically formulated in lightweight, water-based serums or creams for better absorption. A pea-sized amount is sufficient for the face. Over-application may increase dryness or irritation, particularly for new users.

Monderma’s formulations are dermatologically supervised to ensure balance and compatibility of active concentrations for each skin profile.

Who Should Use This Combination

This pairing benefits individuals with:

  • Acne or post-inflammatory marks.
  • Uneven tone or dullness.
  • Rosacea or sensitive skin.
  • Early signs of ageing.

Through Monderma’s free online consultation, healthcare professionals assess skin type and recommend tailored combinations of azelaic acid and niacinamide for specific concerns.

Potential Side Effects & Precautions

Both actives are well-tolerated, though mild irritation can occur initially.

Side EffectLikelihoodManagement
Mild irritation or rednessUncommonReduce frequency or buffer with moisturiser
Temporary drynessOccasionalApply hydrating cream after use
SensitivityRareConduct patch test before first use

Table 2: Potential side effects and precautions for combined use

Avoid layering multiple strong actives at once, and seek professional advice if persistent irritation occurs.

About Monderma’s Personalised Skincare

Monderma provides dermatology-directed, prescription-strength skincare for acne, rosacea, pigmentation, and ageing. Each formulation is prepared in a vegan base and may contain active ingredients such as azelaic acid, niacinamide, or tretinoin.

Visible improvements are often reported within weeks when used consistently under professional guidance. To explore how Monderma’s formulas can enhance your skincare routine, complete a free online consultation.

Conclusion

Azelaic acid and niacinamide deliver proven benefits for acne, redness, and pigmentation, while maintaining hydration and comfort. When used together, they promote clearer, brighter, and more balanced skin.

For personalised guidance, Monderma’s dermatology team offers expert consultations and tailored treatments designed to complement your skincare goals safely and effectively.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. Graupe K, Cunliffe WJ, Gollnick HP, Zaumseil RP. Efficacy and safety of topical azelaic acid (20 percent cream). Cutis. 1996;57(1 Suppl):20-35.
  2. Baliña LM, Graupe K. The treatment of melasma: 20% azelaic acid versus 4% hydroquinone cream. Int J Dermatol. 1991;30(12):893-895.
  3. Elewski BE et al. Comparison of 15% azelaic acid gel and 0.75% metronidazole gel in rosacea. JAMA Dermatol. 2003;139(11):1444-1450.
  4. Gehring W. Nicotinic acid/niacinamide and the skin. J Cosmet Dermatol. 2004;3(2):88-93.
  5. Draelos ZD et al. Niacinamide-containing facial moisturizer benefits subjects with rosacea. Cutis. 2005;76(2):135-141.
  6. Hakozaki T et al. Niacinamide reduces pigmentation and melanosome transfer. Br J Dermatol. 2002;147(1):20-31.
Categories
Treatments

Anti-Ageing Skincare Explained Clearly

Skin ageing starts earlier than most expect, often in the mid-20s, and gradually progresses over time. While the process is natural, environmental and lifestyle factors can accelerate visible signs. Understanding these causes helps guide the best anti-ageing skincare choices, from daily sunscreen to prescription creams.

This guide explains what causes skin ageing, how to recognise its signs, and which evidence-based solutions may help improve texture, firmness, and tone.

How And Why We Experience Ageing Skin

Ageing skin results from a combination of intrinsic and extrinsic factors. Intrinsic ageing refers to natural biological changes that begin in the mid-20s, when collagen and elastin production decline by about 1% each year [1]. Extrinsic ageing comes from external influences such as sunlight, pollution, and free radicals.

A large JAMA Dermatology study found that UV exposure accounted for around 80% of visible facial ageing in participants [2]. Over time, the skin becomes thinner, less elastic, and slower to regenerate. Hormonal changes and lifestyle habits also contribute, while lighter skin tones tend to show wrinkles earlier and darker tones more often develop uneven pigmentation [4,8].

Subtypes Of Ageing Skin

SubtypeDescriptionCommon Areas
Intrinsic AgeingNatural, biologically driven changesWhole body
Extrinsic AgeingUV-induced or environmental ageingFace, neck, arms, legs

Table 1: Subtypes of ageing skin and commonly affected areas

Intrinsic ageing occurs in everyone, but genetics influence its pace. Extrinsic ageing varies more widely and is largely preventable. Sun-exposed areas typically show deeper wrinkles and more discolouration than protected skin [2,6].

What Causes Ageing Skin

The main driver of visible ageing is collagen loss. From the mid-20s, collagen and elastin production slow, reducing firmness and hydration [3]. Hormonal shifts, especially decreased oestrogen, further impact skin strength and moisture [8].

UV radiation, free radicals, smoking, and high-sugar diets accelerate this decline. Studies show that ultraviolet light alone causes up to 80% of premature skin ageing [2,9]. Lifestyle factors like smoking also stiffen collagen fibres and reduce elasticity [10].

How To Spot Premature Ageing

Early signs of ageing often appear around the late 20s, progressing with each decade.

AgeSignsTypical Features
25–30EarlyFine lines, mild collagen loss
40sModerateWrinkles, reduced elasticity
70+AdvancedFragile, thin skin with deep folds

Table 2: Age-related signs and typical features of premature ageing

By assessing photos or video, Monderma’s healthcare professionals can evaluate areas such as the face and neck, determining severity and providing tailored guidance.

Evidence-Based Treatments For Ageing Skin

Clinical research supports the use of topical retinoids, antioxidants, and sunscreen for maintaining youthful skin [12]. For mild cases, over-the-counter products may help. In more advanced cases, prescription-strength formulations offer greater impact.

Monderma’s personalised anti-ageing cream contains tretinoin, a well-studied retinoid shown to increase collagen and smooth fine lines. The treatment can be integrated easily into an existing routine to target wrinkles, uneven tone, and photoaged skin.

Monderma’s Personalised Custom Formula For Fighting Ageing Skin

IngredientStrengthDescriptionEffect On Ageing Skin
Adapalene0.1–0.3%Third-generation retinoid derived from vitamin ABoosts cell turnover and smooths fine lines
Azelaic Acid3–20%Anti-inflammatory compound derived from yeastReduces pigmentation and refines texture
Hydroquinone2–4%Skin-lightening agent targeting melaninFades age spots and evens tone
Niacinamide2–4%Vitamin B3 with antioxidant actionStrengthens barrier and supports elasticity
Tretinoin0.1–1%Prescription retinoidIncreases collagen, reducing wrinkles and firmness loss [11,16]

Table 3: Key active ingredients in Monderma’s custom anti-ageing formula

Common Complications

Without treatment, fine lines deepen and skin thins, making it prone to dryness and slower healing [14]. Sun damage can also cause persistent hyperpigmentation, which becomes harder to treat with age [15]. Fragile blood vessels may increase the risk of redness or rosacea flare-ups.

Practical Tips For Preventing Skin Ageing

  • Use a broad-spectrum SPF 30 or higher every day, even in winter [13,17].
  • Apply a retinoid or antioxidant serum at night to promote renewal [16].
  • Eat a diet rich in whole foods, fruits, and vegetables.
  • Limit alcohol, sugar, and smoking.
  • Exercise regularly and aim for sufficient sleep.

Consistent, gentle care helps maintain firmness and hydration, while sun protection remains the single most effective anti-ageing measure.

Conclusion

Ageing skin reflects both natural biology and environmental exposure. While no treatment can stop the process, evidence-based skincare and lifestyle choices can slow it significantly.

Monderma’s personalised formulations combine prescription retinoids and antioxidants to help improve firmness, texture, and tone. Begin with a free online consultation to explore a tailored anti-ageing routine designed for your skin.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. Shuster S, Black MM, McVitie E. The influence of age and sex on skin thickness, skin collagen and density. Br J Dermatol. 1975;93(6):639-643.
  2. Flament F et al. Effect of the sun on visible clinical signs of aging in Caucasian skin. Clin Cosmet Investig Dermatol. 2013;6:221-232.
  3. Makrantonaki E et al. Identification of Biomarkers of Human Skin Ageing. PLOS One. 2012;7(11):e50393.
  4. Vashi NA et al. Aging Differences in Ethnic Skin. J Clin Aesthet Dermatol. 2016;9(1):31-38.
  5. Farage MA et al. Intrinsic and extrinsic factors in skin ageing: a review. Int J Cosmet Sci. 2008;30(2):87-95.
  6. Jeremian R et al. Skin photoageing following sun exposure. Br J Dermatol. 2024;190(4):590-592.
  7. Ganceviciene R et al. Skin anti-aging strategies. Dermatoendocrinol. 2012;4(3):308-319.
  8. Thornton MJ. Estrogens and aging skin. Dermatoendocrinol. 2013;5(2):264-270.
  9. Rabe JH et al. Photoaging: mechanisms and repair. J Am Acad Dermatol. 2006;55(1):1-19.
  10. Choi JY et al. Agents Targeting Advanced Glycation End-Products for Skin Anti-Aging. Antioxidants (Basel). 2025;14(4):498.
  11. Kligman AM et al. Topical tretinoin for photoaged skin. J Am Acad Dermatol. 1986;15(4 Pt 2):836-859.
  12. Ganceviciene R et al. Skin anti-aging strategies. Dermatoendocrinol. 2012;4(3):308-319.
  13. Young AR et al. Ultraviolet radiation and the skin: Photobiology and sunscreen photoprotection. J Am Acad Dermatol. 2017;76(5S):S100-S109.
  14. Ashcroft GS et al. Aging and wound healing response in a murine model. J Invest Dermatol. 1997;108(4):430-437.
  15. Vashi NA, Kundu RV. Facial hyperpigmentation: causes and treatment. Br J Dermatol. 2013;169(Suppl 3):41–56.
  16. Mukherjee S et al. Retinoids in the treatment of skin aging. Clin Interv Aging. 2006;1(4):327-348.
  17. Randhawa M et al. Daily Use of Broad-Spectrum Sunscreen Improves Photoaging. Dermatol Surg. 2016;42(12):1354-1361.
Categories
Miscellaneous

Adding Mindfulness To Your Daily Skincare Routine

Mindfulness adds depth to a skincare routine by encouraging presence, calm, and awareness. In a fast-paced world, taking time to slow down can improve both skin health and mental well-being.

This guide details how integrating mindfulness into daily skincare turns an ordinary task into a relaxing ritual that nurtures body and mind.

Understanding Mindfulness

Mindfulness means staying aware of the present moment and observing sensations, emotions, and thoughts without judgement. When applied to skincare, it transforms each step into an opportunity for relaxation and self-connection.

Research shows that mindfulness practices reduce stress, which may benefit skin by lowering inflammation linked to acne and rosacea [1].

Benefits Of A Mindful Beauty Routine

A mindful skincare routine encourages slowing down, easing stress, and improving well-being. Studies have found that mindfulness practices can lower cortisol levels, helping reduce stress-related skin concerns [2].

Focusing on how skin feels during each step also improves awareness of its needs. For example, noticing dryness or tightness may guide you toward hydrating products, while observing oiliness might signal the need for lighter formulas.

Steps To Create A Mindful Daily Skincare Routine

1. Set The Scene

Begin by creating a calm environment. Soft lighting, gentle music, or subtle scents such as lavender oil can help quiet the mind and prepare for relaxation. Aromatherapy studies show lavender may reduce anxiety and support a sense of peace [3].

2. Start With A Clean Slate

Cleansing clears the skin and resets the mind. Focus on the temperature of the water and the feel of the cleanser on your skin. Move slowly and notice each motion. Gentle cleansers protect the natural barrier and help remove oil and impurities without irritation [4].

3. Apply Products With Intention

When applying toner, serum, or moisturiser, pay attention to texture and temperature. Massage slowly, breathing evenly, and visualise stress fading away. This approach promotes absorption, boosts circulation, and calms the mind. Finish with a broad-spectrum SPF 30 or higher to protect against UV damage [5].

4. Observe Emotions & Sensations

As you move through your routine, acknowledge emotions such as calm, fatigue, or stress without judgement. Emotional awareness deepens mindfulness and reveals how stress affects your skin, as emotional strain can trigger breakouts or redness [6].

Incorporating A Wellness Journal Into Your Beauty Routine

A wellness journal helps track both emotional patterns and skin changes, strengthening the connection between self-care and mindfulness.

1. Start A Self-Care Journal

Use a dedicated notebook to record skincare steps, products used, and any visible changes. Document how your skin reacts to ingredients and note how you feel during and after your routine. This reflection supports informed skincare choices [7].

2. Use Self-Care Prompts

Prompts can deepen awareness. Try writing about:

  • What self-care means to you.
  • How you feel after completing your routine.
  • What you are grateful for today.

Gratitude and reflection enhance mindfulness and improve emotional well-being [8, 9].

3. Reflect On Progress

Review entries regularly to celebrate progress, whether fewer breakouts, smoother texture, or improved confidence. Recognising positive changes encourages consistency and reinforces the connection between mindfulness and healthy skin [9].

Staying Present During Skincare

Remaining fully present prevents distraction and brings focus to each motion and sensation. To stay mindful:

  • Breathe deeply while applying each product.
  • Notice texture, scent, and temperature.
  • Appreciate the time spent caring for yourself.

Such small actions cultivate gratitude and self-compassion, key elements of both mindfulness and effective self-care [10].

Personalised Skincare With Monderma

Monderma provides prescription skincare treatments for concerns such as acne, ageing, pigmentation, and rosacea. Each formula is tailored to the individual by qualified healthcare professionals.

Using a personalised cream mindfully, paying attention to how it feels and how your skin responds, enhances both effectiveness and relaxation.

Monderma’s free online consultation allows you to explore treatments suited to your skin’s needs while maintaining a mindful, balanced approach to beauty and well-being.

Conclusion

Incorporating mindfulness into your daily skincare routine transforms it from a task into a calming ritual. By setting a peaceful environment, applying products thoughtfully, and journaling reflections, you support both skin health and emotional balance.

Personalised solutions from Monderma can further enhance this practice, combining clinical expertise with mindful self-care for long-term skin confidence and calm.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. Chen Y, Lyga J. Brain-skin connection: Stress, inflammation and skin aging. Inflammation & Allergy-Drug Targets. 2014;13(3):177–190.
  2. Kabat-Zinn J. Full Catastrophe Living. Bantam Books, 2013.
  3. Lee YL et al. A systematic review on the anxiolytic effects of aromatherapy. J Altern Complement Med. 2011;17(2):101–108.
  4. Draelos ZD. The science behind skin care: Cleansers. J Cosmet Dermatol. 2018;17(1):16–22.
  5. Diffey BL. Sunscreens and UVA protection: A major issue of minor importance. Photochem Photobiol. 2009;85(1):15–19.
  6. Jović A et al. The impact of psychological stress on acne. Acta Dermatovenerol Croat. 2017;25(2):113–119.
  7. Smyth JM, Pennebaker JW. Exploring the boundary conditions of expressive writing. Br J Health Psychol. 2008;13(1):1–7.
  8. Baikie KA, Wilhelm K. Emotional and physical health benefits of expressive writing. Adv Psychiatr Treat. 2005;11(5):338–346.
  9. Emmons RA, McCullough ME. Counting blessings versus burdens. J Pers Soc Psychol. 2003;84(2):377–389.
  10. Brown KW, Ryan RM. The benefits of being present: Mindfulness and its role in well-being. J Pers Soc Psychol. 2003;84(4):822–848.
Categories
Ingredients

Exploring Vitamin E Benefits For Skin

Vitamin E plays an important role in maintaining healthy, hydrated, and resilient skin. Recognised for its antioxidant and moisturising properties, it helps defend skin cells from environmental stress such as pollution and UV exposure.

This article explains how vitamin E works, its potential skincare benefits, and practical considerations for safe use as part of a balanced skincare routine.

The Science Behind Vitamin E

Vitamin E refers to a group of eight naturally occurring compounds known as tocopherols and tocotrienols. Alpha-tocopherol is the most biologically active form and the one most often used in skincare formulations [2].

Vitamin E is fat-soluble and accumulates in the outer layer of the skin, where it supports the natural barrier and reduces moisture loss. It also helps neutralise free radicals generated by sunlight and pollution, reducing oxidative stress that contributes to early skin ageing [1, 2].

Is Vitamin E Good For Skin?

Vitamin E offers antioxidant protection and may help reduce dryness while supporting overall skin comfort [2]. Research indicates that people with chronic inflammatory skin conditions such as atopic dermatitis or psoriasis often show lower serum vitamin E levels, suggesting a link between the nutrient and skin health [3].

However, evidence for vitamin E creams or oils as a treatment for eczema or other inflammatory skin diseases remains limited. Topical use should therefore focus on barrier support and hydration rather than disease management [3].

Applications Of Vitamin E In Skincare

Vitamin E appears in many topical products, each with different textures and benefits.

ApplicationDescriptionTypical Benefit
Vitamin E OilConcentrated form for direct useHelps relieve dryness and support barrier repair
Vitamin E SerumLightweight formulaMay improve radiance and firmness
Vitamin E CreamMoisturising base for daily useHelps reduce dryness and support elasticity

Table 1: Common topical forms of vitamin E

Vitamin E In Natural Skincare

Vitamin E is widely included in natural and plant-based skincare because it mixes well with oils such as jojoba and shea butter. These blends enhance hydration and softness while remaining gentle on sensitive skin.

A balanced diet rich in nutrients including vitamin E also contributes to overall skin health and resilience [1].

Vitamin E For Skin Repair & Radiance

Vitamin E may help stabilise collagen and protect against free-radical damage that contributes to fine lines and uneven tone. Evidence for scar reduction is inconsistent, though vitamin C shows stronger data for supporting collagen formation [5, 6].

When combined with vitamin C, vitamin E provides complementary antioxidant activity, which can improve luminosity and help protect from UV-induced oxidative stress [4].

AspectPossible Role Of Vitamin E
Moisture RetentionStrengthens barrier to reduce water loss [2]
Inflammation SupportMay assist mild eczema symptoms [3]
UV ProtectionHelps limit oxidative damage [2]
Wound HealingLinked with tissue repair; evidence limited [6]

Table 2: Summary of vitamin E skin functions

Combining Vitamin E With Other Ingredients

Vitamin E performs well when paired with hydrating and soothing ingredients such as:

  • Jojoba oil or shea butter for deep moisturisation.
  • Aloe vera for calming post-sun care.
  • Vitamin C for enhanced antioxidant protection [4].

Such combinations support both natural and prescription skincare routines focused on gentle barrier repair.

Monderma’s Personalised Approach

Monderma provides prescription skincare for acne, ageing, pigmentation, and rosacea. Each formulation is reviewed by healthcare professionals to ensure suitability.

The base cream used in Monderma prescriptions includes vitamin E (as tocopheryl acetate) along with jojoba oil and shea butter, helping maintain hydration while supporting the action of other active ingredients.

Considerations When Using Vitamin E

Possible Reactions

A small number of users experience irritation or redness when applying vitamin E. Conduct a patch test before full use and discontinue if sensitivity occurs [2].

Effective Strengths

Formulations typically contain 0.5 to 1 percent vitamin E, offering measurable antioxidant support without increasing the risk of irritation [2]. Professional guidance helps determine suitable concentrations for each skin type.

Conclusion

Vitamin E provides proven antioxidant and moisturising benefits that help maintain healthy, hydrated, and radiant skin. Although evidence for certain therapeutic uses remains limited, it remains a valuable supportive ingredient in daily skincare.

For tailored prescription skincare containing vitamin E and complementary actives, complete your free consultation for a professional review.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. NHS. Vitamins and Minerals – Vitamin E. 2020.
  2. Nachbar F, Korting HC. The Role of Vitamin E in Normal and Damaged Skin. J Mol Med (Berl). 1995; 73(1): 7–17.
  3. Liu X et al. Serum Vitamin E Levels and Chronic Inflammatory Skin Diseases. PLoS ONE. 2021; 16(12): e0261259.
  4. Pullar JM et al. The Roles of Vitamin C in Skin Health. Nutrients. 2017; 9(8): 866.
  5. Wang Z et al. Vitamin E Regulates Collagen via Antioxidant Effects and the TGF-β/Smads Pathway. Antioxidants (Basel). 2024; 13(7): 847.
  6. NHS Wales. Scars. 2024.
Categories
Treatments

Skincare For Rosacea: Treatment & Triggers

Rosacea is a chronic inflammatory skin condition affecting around 1.65% of people in the UK [1,9] and over 5% globally [4]. It commonly appears after age 30 and presents with facial redness, visible blood vessels, irritation, and sometimes acne-like bumps [2].

This guide explores rosacea symptoms, triggers, and treatments including dermatologist-supervised skincare to help manage flare-ups safely and effectively.

Understanding The Types Of Rosacea

Rosacea has four recognised subtypes, often overlapping and evolving over time [10].

SubtypeDescription & EffectsPrevalenceCommon Areas
ErythematotelangiectaticRedness, visible vessels, and burning57% [3]Nose, cheeks, chin
PapulopustularRedness with acne-like bumps (no blackheads)43% [3]Forehead, cheeks, chin
PhymatousThickened, bumpy skin (often on the nose)7% [3]Nose, ears
OcularEye dryness, burning, and irritation11% [3]Eyes, eyelids

Table 1: Common rosacea subtypes and prevalence

Subtypes can co-exist or shift over time, requiring professional evaluation for tailored care.

Common Triggers Of Rosacea

Flare-ups are highly individual, but several common triggers frequently worsen redness and irritation [5,6].

TriggerEffect On SkinPrevalenceManagement Tip
Sun ExposureUV rays dilate blood vessels and damage skin barrier81% [6]Apply SPF 30+ mineral sunscreen daily [7]
StressReleases inflammatory neuropeptides79% [6]Use mindfulness or relaxation exercises [5]
Extreme WeatherHeat or wind aggravates flushing75% hot / 46% cold [6]Layer clothing & protect face outdoors
AlcoholExpands blood vessels, increasing redness52% [6]Limit red wine and strong spirits [5]
ExerciseRaises body temperature and facial flushing56% [6]Cool skin, hydrate, apply SPF if outdoors
Spicy FoodCapsaicin widens vessels and triggers burning45% [6]Choose mild flavours [5]
Hot DrinksHeat triggers flushing36% [1]Try iced versions
Harsh SkincareFragrance or alcohol increases sensitivity41% [6]Use gentle, fragrance-free cleansers [5]

Table 2: Common rosacea triggers and management strategies

Tracking triggers with a healthcare professional helps refine personalised management plans.

Diagnosing Rosacea

Diagnosis is clinical and based on visible redness, vascular changes, and inflammation in the absence of blackheads. According to NHS guidance, assessment includes evaluating severity and identifying aggravating factors [7].

Monderma’s clinicians review photographs or video consultations to confirm type and recommend suitable prescription skincare.

Effective Rosacea Treatments

Evidence-Based Ingredients

Topical therapies help calm inflammation, reduce redness, and improve barrier function.

IngredientStrengthWhat It IsHow It Helps Rosacea
Azelaic Acid3–20%Dicarboxylic acid from grainsCalms inflammation & reduces redness [7]
Niacinamide2–4%Vitamin B3 derivativeStrengthens barrier & reduces sensitivity
Ivermectin1%Antiparasitic compoundTargets Demodex mites linked to rosacea [13]

Table 3: Common Prescription Actives For Rosacea Management

Combination formulas prescribed by a healthcare professional can address both inflammation and microbial imbalance.

Prescription Formulations

Monderma offers dermatologist-directed treatments containing medical-grade actives such as azelaic acid, niacinamide, and ivermectin. These ingredients target redness, strengthen skin resilience, and reduce mite-related irritation.

Managing Complications

Without management, rosacea can lead to persistent redness, thickened skin, or eye complications. Around 20% of advanced cases involve ocular symptoms such as dryness or discomfort [8,9,12].

Psychological impacts are also common, highlighting the importance of early, compassionate treatment and ongoing support.

Practical Skincare Tips For Rosacea

  • Use gentle, fragrance-free cleansers twice daily.
  • Apply prescribed rosacea cream as directed by your clinician.
  • Always wear SPF 30+ mineral sunscreen, even on cloudy days [7].
  • Avoid alcohol-based or exfoliating products [6,11].
  • Keep a trigger diary to monitor food, weather, or stress patterns.
  • Stay consistent and review progress regularly with a healthcare professional.

Conclusion

Rosacea management combines identifying triggers, using gentle skincare, and applying targeted prescription treatments. With consistent SPF use, avoidance of irritants, and professional guidance, most people achieve noticeable improvement in redness and comfort.

For expert-led rosacea care, complete a free consultation with Monderma today and share this article to help others better understand rosacea management.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. NICE. Rosacea: Prevalence. Clinical Knowledge Summaries, 2023.
  2. Patient.info. Rosacea. Updated May 2023.
  3. Barakji YA, et al. Assessment of Frequency of Rosacea Subtypes in Patients With Rosacea. JAMA Dermatol. 2022;158(6):678-686.
  4. Gether L, Overgaard LK, Egeberg A, et al. Prevalence and risk of rosacea: a systematic review and meta-analysis. Br J Dermatol. 2018;179(2):282-289.
  5. National Rosacea Society. Coping With Common Rosacea Triggers. 2018.
  6. National Rosacea Society. Rosacea Triggers Survey. Accessed July 2025.
  7. NHS. Rosacea. 2023.
  8. DermNet NZ. Ocular Rosacea. Accessed July 2025.
  9. Spoendlin J, Voegel JJ, Jick SS, Meier CR. Epidemiology of Rosacea in the U.K. Br J Dermatol. 2012;167(3):598-605.
  10. Tan J, Berg M, Gallo RL, Del Rosso JQ. Applying the Phenotype Approach for Rosacea. Br J Dermatol. 2018;179(3):741-746.
  11. Searle T, Ali FR, Carolides S, Al-Niaimi F. Rosacea and Diet: What Is New in 2021? J Clin Aesthet Dermatol. 2021;14(12):49-54.
  12. National Rosacea Society. Ocular Rosacea Can Threaten Sight. Rosacea Review. Winter 2004.
  13. NICE. Rosacea: Management. Clinical Knowledge Summaries, 2023.
Categories
Miscellaneous

Fitzpatrick Skin Types Guide & Sun Protection

Understanding your skin type helps tailor effective sun protection and skincare. The Fitzpatrick scale, developed by Dr. Thomas Fitzpatrick in 1975, classifies skin into six categories based on response to ultraviolet (UV) radiation [1,5]. This system remains central in dermatology for assessing sunburn risk, pigmentation changes, and long-term UV-related damage.

This article outlines each Fitzpatrick skin type and explains how to protect skin from sun exposure safely and effectively.

What Is The Fitzpatrick Skin Type Scale?

The Fitzpatrick scale measures how skin reacts to sunlight, from burning to tanning tendencies. It categorises six skin types, guiding clinicians and individuals in sun protection, skincare, and certain treatment decisions [1,5,6].

Fitzpatrick Skin TypeKey CharacteristicsResponse To SunRisk Level
1Very fair; red or blonde hair, light eyesAlways burns, never tansHigh
2Fair; burns easily, tans minimallyBurns easilyHigh
3Medium; light brown or European skinMay burn, tans graduallyModerate
4Olive; Mediterranean or Hispanic skinRarely burns, tans easilyLower
5Brown; Middle Eastern or Indian skinRarely burns, tans easilyLower
6Dark brown to black; African heritageAlmost never burnsLowest

Table 1: Fitzpatrick skin types and sun responses

Sun Protection For Fair Skin

Skin Type 1: Very Fair Skin

Individuals with skin type 1 have very pale complexions and often red or blonde hair. They burn easily and rarely tan, facing the highest risk of sun damage. Strict protection is essential [1,6].

Recommended Protection:

  • Apply broad-spectrum SPF 30+ daily [2,3].
  • Reapply every 2 hours or after sweating/swimming.
  • Wear wide-brimmed hats, sunglasses, and long sleeves.
  • Seek shade between 11 am and 3 pm [2].

Skin Type 2: Fair Skin

This type also burns readily and tans only slightly. Consistent use of high-SPF sunscreen and protective clothing is vital to prevent early skin ageing and damage.

Sun Protection For Medium & Olive Skin

Skin Type 3: Medium Skin

This type may burn initially but tans gradually over time. Individuals of European descent often fall within this category. Though less vulnerable than fair types, continued sun care prevents cumulative damage [6].

Key Tips:

  • SPF 30+ daily for outdoor activity.
  • Limit midday exposure.
  • Include protective hats and eyewear.

Skin Type 4: Olive Skin

This type burns infrequently and tans easily, common among Mediterranean, Hispanic, and South Asian individuals. Some natural protection exists, but UV exposure still contributes to long-term pigmentation and photoageing [6].

Key Tips:

  • Use SPF 30+ for daily exposure.
  • Reapply during prolonged outdoor activity.
  • Incorporate antioxidant skincare for added protection.

Sun Protection For Darker Skin

Skin Type 5: Brown Skin

People with skin type 5 tan easily and seldom burn. Although UV damage is less visible, it can still cause uneven tone, hyperpigmentation, and long-term ageing [6].

Recommendations:

  • Apply SPF 15+ on exposed areas [2,6].
  • Protect against reflective UV from water and snow.
  • Check for new or changing moles regularly.

Skin Type 6: Dark Brown Or Black Skin

This type rarely burns and offers stronger natural protection. However, melanoma and other sun-induced conditions can still occur [6].

Recommendations:

  • SPF 15+ daily for uncovered areas.
  • Maintain sun protection during extended exposure.
  • Monitor for pigment changes or irregular spots.

Tailored Sun Protection Strategies

All skin types benefit from consistent UV protection. The approach should match your individual risk level, daily habits, and any treatments that may increase photosensitivity.

For Skin Types 1–2:

  • SPF 30+ broad-spectrum sunscreen daily [2,3].
  • Avoid peak UV hours.
  • Combine with UV-protective fabrics.

For Skin Types 3–4:

  • SPF 30+ recommended.
  • Reapply every 2 hours when outdoors.
  • Add antioxidant serums to support skin resilience.

For Skin Types 5–6:

  • SPF 15–30 on exposed skin [2,6].
  • Maintain coverage during prolonged exposure.
  • Continue protective habits even in overcast weather.

The Importance Of Year-Round Protection

UV radiation penetrates clouds and reflects from surfaces like snow and water. This means sun protection is necessary even in winter or overcast conditions [2,3].

In the UK, melanoma skin cancer affects approximately 17,500 people annually, making it the fifth most common cancer [4]. Preventive sun care plays a key role in reducing these risks.

Photosensitising Treatments & UV Sensitivity

Certain prescription skincare ingredients, including tretinoin and azelaic acid, can heighten sun sensitivity. Consistent daily sunscreen use protects skin from irritation and damage while using such treatments [7].

Healthcare professionals recommend introducing SPF as a core part of any skincare regimen, especially for individuals using retinoids or exfoliating acids.

Monderma’s Role In Personalised Skin Health

Monderma provides personalised, prescription-based skincare for concerns such as ageing, pigmentation, and rosacea, all of which can be worsened by UV exposure.

Ingredients like tretinoin support cell renewal for photoaged skin, while azelaic acid helps calm redness and improve uneven tone. Because these ingredients may increase sensitivity to UV radiation, consistent sun protection is vital.

Start with a free consultation to receive a dermatologist-guided skincare plan designed around your skin type and sun protection needs.

Conclusion

Recognising your Fitzpatrick skin type helps you adopt safe, tailored sun protection habits. Whether your skin burns easily or rarely at all, consistent SPF use, reapplication, and sun-smart habits are key to long-term skin health.

Prescription skincare may improve tone and texture but always requires complementary UV protection. For professional guidance, explore Monderma’s personalised skincare options today and share this article to help others protect their skin year-round.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. Sharma AN, Patel BC. Laser Fitzpatrick Skin Type Recommendations. StatPearls. 2025.
  2. NHS. Sunscreen and Sun Safety. 2024.
  3. Cancer Research UK. Sun Safety | Reduce Your Skin Cancer Risk. 2025.
  4. Cancer Research UK. Melanoma Skin Cancer Statistics. 2025.
  5. DermNet NZ. Skin Phototype (Fitzpatrick Skin Type). 2024.
  6. DermNet NZ. Common Skin Lesions: Ageing Skin. 2024.
  7. BMJ Drug & Therapeutics Bulletin. Tretinoin for Sun-Aged Skin. 1996.
Categories
Ingredients

Hydroquinone Cream: How Effective Is It?

Hydroquinone is a prescription-strength topical ingredient widely used for managing hyperpigmentation, melasma, and dark spots. It works by reducing melanin formation, leading to a more even-looking skin tone.

This guide explains how hydroquinone works, its effectiveness, common side effects, safe usage guidelines, and available alternatives.

What Is Hydroquinone?

Hydroquinone is a depigmenting agent that decreases melanin production in the skin. It helps reduce the visibility of dark spots, acne marks, and uneven tone when used under medical supervision.

Clinical studies show that hydroquinone can improve melasma in approximately 70% of users within 12 weeks of regular use [1]. Because of its potency and risk profile, hydroquinone is prescription-only in the UK.

How Hydroquinone Works

Hydroquinone inhibits tyrosinase, an enzyme that converts tyrosine into melanin. By slowing this process, it helps lighten areas of hyperpigmentation.

A 4% hydroquinone formulation is considered clinically effective for post-inflammatory hyperpigmentation, typically showing visible change within 8–12 weeks [2]. Continued use beyond six months is not recommended without medical guidance [8].

Historical Context & Regulation

Hydroquinone was first used in the 19th century in photographic processing. In the 1950s, researchers identified its potential in reducing pigmentation, leading to dermatological use [4].

However, long-term safety concerns, such as ochronosis (a rare blue-black discoloration), led to restrictions in many countries. Hydroquinone is now prescription-only in the UK to ensure safe, monitored use [5].

Common Uses Of Hydroquinone

Hydroquinone targets pigment-related conditions including:

  • Melasma (hormonal pigmentation)
  • Post-acne marks and sun spots
  • Solar lentigines and age-related pigmentation

When combined with other active ingredients such as retinoids, hydroquinone can enhance results for complex hyperpigmentation cases [6]. A healthcare professional ensures suitability and guides safe treatment.

Effectiveness Of Hydroquinone

Real-World Results

Clinical research supports hydroquinone’s efficacy for melasma and dark spot reduction. In a 2006 study, 4% hydroquinone achieved significant pigmentation improvement within 12 weeks [7].

Typical Results Timeline

Time FrameExpected Change
4–6 weeksEarly fading of dark marks
8–12 weeksNoticeably more even tone
>12 weeksSlower improvement, maintenance phase

Table 1: Typical results timeline for hydroquinone

Hydroquinone should be reassessed by a healthcare professional after 3 months to determine ongoing suitability [8].

Potential Side Effects

While generally well tolerated when used correctly, hydroquinone may cause temporary irritation or redness in some users.

Common & Rare Reactions

Side EffectLikelihoodManagement
Mild irritationCommon (5–10%)Reduce frequency, use moisturiser
Allergic reactionUncommon (2–5%)Discontinue & seek medical advice
OchronosisRare (<1%)Stop treatment, consult clinician

Table 2: Common and rare side effects of hydroquinone

A 2013 comparative trial reported mild irritation in about 5% of users at 4% strength [9]. Always perform a patch test before use.

Safe Use & Practical Tips

  • Clean Skin: Apply only to clean, dry skin on affected areas.
  • Sun Protection: Daily SPF 30+ prevents pigmentation rebound [11].
  • Short-Term Use: Limit application to 3–6 months unless directed by a clinician.
  • Avoid Mixing: Do not use with peroxide-based products to reduce irritation risk.
  • Follow Supervision: Always use under healthcare direction.

Personalised Treatment Considerations

Skin Type & Sensitivity

Hydroquinone may not suit highly sensitive or darker skin tones due to higher ochronosis risk [12]. A clinician can advise suitable strengths or alternatives based on your skin history.

Combination Therapy

Combining hydroquinone with tretinoin enhances cell turnover and overall tone correction [13]. Some protocols pair hydroquinone with mild chemical exfoliants or laser therapy, but these should only be done under professional supervision.

Alternatives To Hydroquinone

Those preferring gentler pigment correction may consider:

  • Vitamin C: Brightens and protects against free-radical damage.
  • Kojic Acid: Shown to improve pigmentation over 8 weeks [14].

These alternatives act more gradually but can be better tolerated, especially for sensitive skin.

Conclusion: Is Hydroquinone Right For You?

Hydroquinone remains one of the most studied and effective options for addressing hyperpigmentation and uneven tone. However, its strength means professional supervision is essential. When used responsibly alongside SPF and supportive skincare it can deliver visible improvement within weeks while maintaining skin safety.

For tailored care, complete a free online consultation and share this article to help others understand safe, effective hyperpigmentation treatment.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. McKesey J, Tovar-Garza A, Pandya AG. Melasma Treatment: An Evidence-Based Review. Am J Clin Dermatol. 2020;21(2):173–225.
  2. Chandra M, et al. Hydroquinone therapy for post-inflammatory hyperpigmentation secondary to acne. Acta Derm Venereol. 2012;92(3):232–5.
  3. Searle T, et al. Hydroquinone: Is This Toxic Beauty At Its Best? Clin Exp Dermatol. 2021.
  4. History of Hydroquinone. Indian J Derm Venereol Leprol. 2022.
  5. Charlín R, et al. Hydroquinone-induced exogenous ochronosis. Dermatol Ther. 2007;20:308–13.
  6. Fabian IM, et al. Topical Hydroquinone for Hyperpigmentation: A Narrative Review. Clin Cosmet Investig Dermatol. 2023.
  7. Rendon M, et al. Treatment of Melasma. J Am Acad Dermatol. 2006;54:S272–81.
  8. British Association of Dermatologists. Specials Recommended for Skin Disease. 2018.
  9. Monteiro RC, et al. Comparative Study of 4% Hydroquinone vs 0.75% Kojic Acid. Indian J Derm Venereol Leprol. 2013;79:701–2.
  10. Schwartz C, et al. Hydroquinone. StatPearls. 2023.
  11. Arellano I, et al. Melasma in Latin America: Therapy Options. J Eur Acad Derm Venereol. 2012;26:611–18.
  12. Wawrzyk-Bochenek I, et al. Kojic Acid & Hyperpigmentation Reduction Using Hyperspectral Imaging. J Clin Med. 2023;12(7):2710.
  13. Grimes PE, et al. Treatment of Melasma with 4% Hydroquinone + 0.05% Tretinoin. J Clin Aesthet Dermatol. 2013;6(11):32–38.
Categories
Treatments

A Comprehensive Guide For Treating Acne

Acne is one of the most common skin conditions worldwide, often starting in adolescence and sometimes continuing into adulthood. It can impact self-esteem and overall well-being, making informed treatment vital.

This guide explains acne’s causes, subtypes, and treatment options, helping individuals understand how to achieve clearer, healthier skin safely and effectively.

What Is Acne?

Acne occurs when hair follicles become blocked by oil, dead skin cells, and bacteria, leading to inflammation and spots. It affects up to 95% of people aged 11 to 30 in the UK, with most cases peaking in teenage years [1,3]. Around 10–15% of adults aged 35–44 continue to experience acne [2].

While most common on the face, acne can also appear on the back (up to 60%) and chest (around 15%) [1].

Historical Context & Understanding

Records of acne date back to ancient Egypt, around 1550 BCE, describing skin lesions resembling cystic acne [12]. By the 19th century, scientists recognised the link between hormones and oil production. Modern research now explores the combined roles of genetics, hormones, and environment in acne’s development.

Subtypes Of Acne & Their Features

Acne appears in several forms, from mild to severe. Each type requires different management strategies.

Acne SubtypeDescriptionCommon Areas
BlackheadsSmall, dark, non-inflammatory bumpsForehead, nose, chin
WhiteheadsSmall, light, non-inflammatory bumpsForehead, nose, chin
PapulesTender, red, inflamed bumpsForehead, cheeks, jawline
PustulesRed bumps with white pus tipsForehead, cheeks, jawline
NodulesHard, deep-seated lumpsCheeks, jawline
CystsLarge, boil-like, painful lumpsCheeks, jawline

Table 1: Common acne subtypes and locations

A healthcare professional can identify acne type accurately and suggest a suitable management plan.

What Causes Acne?

Excess sebum (oil) production combines with dead skin and bacteria, blocking follicles and causing inflammation. Hormonal changes, particularly during puberty, are a primary trigger [2].

Genetics also play a strong role. Individuals with parents who had severe acne are more likely to develop similar patterns [1]. Maintaining hydration and using non-comedogenic moisturisers can support skin balance.

Contributing Factors

Hormones, diet, stress, and environment can worsen acne.

  • Diet: A 2020 JAMA Dermatology study linked high-sugar diets with increased acne risk [7].
  • Lifestyle: Smoking has been associated with acne scarring, and humid climates can worsen breakouts [6].
  • Medications: Certain drugs, such as corticosteroids, may temporarily aggravate acne by altering skin turnover.

Diagnosing Acne

A clinician assesses acne severity based on lesion type and count.

  • Mild-to-Moderate: Up to 34 inflammatory lesions or 1–2 nodules
  • Moderate-to-Severe: 35+ lesions or more than 3 nodules

Accurate diagnosis follows NICE guidelines, which recommend reviewing medical history and potential triggers [8].

Monderma’s healthcare professionals review photographs or video consultations to ensure accurate classification before treatment planning.

Conditions That Mimic Acne

Some conditions may resemble acne but require different care.

  • Rosacea: Often shows redness and visible vessels; affects about 1.65 per 1000 UK adults [10].
  • Folliculitis: Caused by infection or shaving irritation, producing small pustules [11].

A healthcare professional can distinguish these for proper management.

Effective Acne Treatment Options

When standard skincare is insufficient, prescription-based topical treatments can help. Monderma’s clinicians provide personalised formulations containing clinically supported ingredients.

Key Active Ingredients & Their Roles

IngredientStrengthWhat It IsHow It Helps Acne
Adapalene0.1–0.3%A third-generation retinoidPrevents clogged pores & reduces breakouts
Azelaic Acid3–20%Natural dicarboxylic acidReduces bacteria & brightens dark marks
Clindamycin1%Topical antibioticTargets acne-causing bacteria
Niacinamide2–4%Vitamin B3 derivativeRegulates oil & calms redness
Tretinoin0.01–0.1%Prescription retinoidBoosts cell turnover to unclog pores

Table 2: Active ingredients commonly used in acne treatment

All ingredients should be used under medical supervision to ensure safety and suitability.

Practical Tips For Acne-Prone Skin

  • Cleanse Gently: Use mild, non-stripping cleansers twice daily.
  • Apply Treatments Sparingly: Use a pea-sized amount to reduce dryness or irritation.
  • Moisturise Daily: Non-comedogenic moisturisers help protect the skin barrier.
  • Sun Protection: SPF 30 or higher prevents photosensitivity from active ingredients.
  • Be Patient: Noticeable results often take 6–8 weeks [9].

Advanced Acne Scar Treatment Options

For persistent scars, dermatologists may recommend:

  • Chemical Peels: Remove surface cells to smooth texture.
  • Laser Resurfacing: Stimulates collagen to refine deep scars.

Both methods can improve acne scarring when performed under professional supervision. Individual results vary depending on scar depth and skin type.

Complications Of Untreated Acne

Without treatment, severe acne can lead to permanent atrophic scars such as ice-pick or rolling scars. Emotional and social effects are also common, highlighting the importance of early intervention.

Monderma’s Personalised Acne Care Approach

Monderma’s clinicians offer evidence-based acne treatments customised to skin type and severity. Through an online consultation, patients receive dermatologist-reviewed plans containing proven active ingredients.

This individualised method supports both skin clarity and long-term maintenance.

Conclusion

Acne is manageable with a tailored, consistent approach. Understanding its causes and treatment options empowers individuals to reduce breakouts, fade scars, and restore confidence.

You can complete a quick, free online consultation reviewed by a GPhC-registered prescriber to see if a prescription-strength formula could be right for your skin.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. NHS. Acne. 2020.
  2. Vasam M, et al. Acne vulgaris: A review of the pathophysiology, treatment, and prevention. Cureus, 2023.
  3. Bhate K, Williams HC. Epidemiology of acne vulgaris. Br J Dermatol. 2013;168(3):474–485.
  4. Del Rosso JQ. The primary role of sebum in the pathophysiology of acne. J Dermatol Treat. 2024.
  5. Teder-Laving M, et al. Genome-wide meta-analysis identifies novel loci conferring susceptibility to acne. Eur J Hum Genet. 2024.
  6. Capitanio B, Sinagra JL, Bordignon V, et al. Acne and smoking. Dermatology, 2009;218(2):119–124.
  7. Penso L, Dréno B, et al. Association Between Adult Acne and Dietary Behaviors. JAMA Dermatol. 2020;156(8):854–862.
  8. NICE. Acne vulgaris: management. NG198, 2021.
  9. Callender VD, Baldwin H, Cook-Bolden FE, et al. Effects of Topical Retinoids on Acne and Post-inflammatory Hyperpigmentation in Patients with Skin of Color. Dermatol Ther (Heidelb). 2021;11(1):1–15.
  10. Spoendlin J, Voegel JJ, Jick SS, Meier CR. A study on the epidemiology of rosacea in the U.K. Br J Dermatol. 2012;167(3):598–605.
  11. Dermatology of Seattle. Folliculitis: Why You Might Mistake It for Acne. 2025.
  12. SLMD Skincare. The (Bumpy!) History of Acne Treatments. 2024.
Categories
Miscellaneous

The Future Of Dermatology With AI Skin Analysis

Technological innovation is reshaping dermatology by combining artificial intelligence (AI), telemedicine, and personalised treatments to improve accessibility and precision in skincare. These advances strengthen diagnostic accuracy, streamline consultations, and empower patients to manage their skin health more effectively.

This article explores how AI and emerging technologies support early detection, enhance personalised dermatological care, and transform everyday skincare.

AI’s Transformative Role In Dermatology

AI is increasingly used to analyse skin images, helping identify abnormalities such as melanoma with sensitivity rates above 90%, comparable to dermatologist assessments [1]. Such precision supports earlier intervention and more efficient triage.

AI also enhances access to dermatology services in rural or underserved areas. Remote skin assessments can deliver timely guidance, reducing healthcare burdens. By 2023, global teledermatology platforms recorded more than one million consultations, demonstrating improved accessibility.

Monderma integrates these advances to offer tailored skincare through digital consultations, enabling users to receive professional guidance before starting treatment.

AI Skin Analysis: Precision & Early Detection

AI-powered image analysis uses deep learning to evaluate moles, rashes, and other skin changes. Sensitivity for detecting malignant lesions has been reported between 64.8% and 92% [2]. These systems complement clinical expertise by supporting decision-making and prioritising urgent cases.

AI skin analysis may also assist in managing conditions such as acne or rosacea, though its use for monitoring treatment progress remains under active research [8].

Platforms like Monderma allow users to begin their journey with a free online consultation, receiving tailored guidance for concerns like pigmentation or breakouts [3].

Online Skin Consultations: Accessibility & Engagement

Online consultations allow patients to connect with dermatology professionals from home. This reduces travel and can speed up assessment times. NHS data from 2022 reported significant reductions in waiting times for non-urgent dermatology cases through teleconsultation [3].

These services also improve continuity of care, allowing ongoing reviews and progress tracking. Monderma’s platform provides secure dashboards where users can monitor results and request adjustments following clinical review.

Genetic Skin Conditions & Personalised Approaches

AI has emerging applications in understanding and managing genetic skin disorders such as psoriasis and epidermolysis bullosa simplex. By analysing genetic data, AI identifies biomarkers and patterns that inform targeted care plans [4].

This enables more individualised regimens, potentially reducing flare-ups and improving quality of life. Such approaches reflect the move toward evidence-based, precision dermatology.

AI In Healthcare Roles & Professional Collaboration

AI enhances, rather than replaces, the role of healthcare professionals. Dermatologists use AI tools to support diagnostic accuracy and workflow efficiency. In 2025, NICE issued an early value assessment recognising AI’s potential for triaging skin lesions in suspected cancer referrals [5].

This partnership allows clinicians to focus on complex cases while integrating AI for early detection and data analysis.

AI is also transforming dermatology training, enabling practitioners to allocate more time to patient communication and long-term care strategies.

Future Innovations In Dermatology

Technological developments continue to drive progress in skin health monitoring and treatment.

Wearable Devices & Skin Monitoring

Wearable technology tracks physiological changes and hydration, offering real-time insights for conditions like atopic dermatitis [7]. Continuous monitoring supports early intervention and long-term management.

AI-Powered Dermatological Products

AI-driven skincare systems assess user data to recommend personalised ingredients or formulations. While adherence improvements vary, personalised digital skincare has been shown to enhance engagement and satisfaction [7].

AI also streamlines product formulation by analysing ingredient safety and compatibility, accelerating the creation of new dermatological products.

Conversational AI & Patient Education

Chatbots and virtual assistants now assist in dermatology education, providing evidence-based responses to common questions. These systems can help users understand acne, eczema, or pigmentation management in real time [6].

Early findings suggest conversational AI improves patient understanding by up to 35% in certain dermatology education studies, though further evaluation is ongoing.

Historical Context & Future Directions

From early herbal remedies to modern AI-enhanced dermatology, skin care has continuously evolved. Combining traditional knowledge with advanced analytics fosters more holistic and sustainable care models.

AI’s predictive capacity could enable earlier identification of risk factors, aligning with the broader move toward preventive and personalised medicine.

Monderma: Personalised Skincare Solutions

Monderma provides prescription-based, dermatologist-reviewed formulations for skin concerns such as acne, ageing, pigmentation, and rosacea. Treatments are personalised following an online consultation with ongoing professional support.

This process reflects the direction of modern dermatology: precise, accessible, and scientifically supported skincare.

Conclusion

AI and digital innovation are redefining dermatology by improving access, precision, and patient engagement. From advanced image analysis to wearable devices, technology enables proactive and personalised care.

Platforms like Monderma are leading this transformation, offering prescription skincare designed to complement professional guidance. Explore your personalised options through a free online consultation with a GPhC-registered prescriber.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. Esteva A, Kuprel B, Novoa RA, et al. Dermatologist-level classification of skin cancer with deep neural networks. Nature. 2017;542(7639):115-118.
  2. Han SS, Kim MS, Lim W, Park GH, Park I, Chang SE. Augmented Intelligence Dermatology: Deep Neural Networks Empower Medical Professionals in Diagnosing Skin Cancer and Predicting Treatment Options for 134 Skin Disorders. Journal of Investigative Dermatology.
  3. NHS England. A teledermatology roadmap: implementing safe and effective teledermatology triage pathways and processes. 2023.
  4. Smith P, Johnson CE, Haran K, et al. Advancing Psoriasis Care through Artificial Intelligence. Curr Dermatol Rep. 2024.
  5. National Institute for Health and Care Excellence (NICE). Artificial intelligence (AI) technologies for assessing and triaging skin lesions referred to the urgent suspected skin cancer pathway: early value assessment. NICE HTE24. 2025.
  6. Kong JD, Kim J, Kim S, et al. The Comparative Sufficiency of ChatGPT, Google Bard, and Bing AI in Answering Diagnosis, Treatment, and Prognosis Questions About Common Dermatological Diagnoses. JMIR Dermatol. 2024;7:e60827.
  7. PubMed. Skin sensing and wearable technology as tools to measure atopic dermatitis. 2024.
  8. How Well Can AI Diagnose and Monitor Acne? Dermatology Times. Published June 1, 2022. Accessed July 8, 2025.
Categories
Ingredients

Tretinoin Before & After Timeline & Results

Tretinoin, a prescription-only vitamin A derivative, is widely used to improve the appearance of acne-prone and photoaged skin [1]. It supports cell renewal and collagen stimulation, making it a key ingredient in dermatologist-directed routines.

This article explores its science, effects, usage, and what to expect from consistent application.

Understanding Tretinoin

Tretinoin is a topical retinoid prescribed for acne and photoaged skin. It is available in various strengths (typically 0.01% to 0.1%) and formulations, such as creams or gels [2]. Tretinoin should only be used under healthcare supervision to ensure suitability for individual skin types.

The Science Behind Tretinoin

Tretinoin interacts with retinoic acid receptors in skin cells, supporting normal cell turnover and collagen production. These actions can help improve the texture and appearance of the skin over time [1].

Developed in the 1960s by Dr. Albert Kligman and Dr. James Fulton, it remains a well-studied topical treatment in dermatology.

Tretinoin Vs Retinol

Retinol is an over-the-counter cosmetic ingredient that must convert into retinoic acid before becoming active. Tretinoin, by contrast, is already in its active form, meaning it works more directly within the skin [1]. Because of its potency, tretinoin is only available on prescription.

Tretinoin & Skin Cell Turnover

By supporting cell renewal, tretinoin helps prevent pore blockage and surface buildup that may contribute to acne formation. Regular use can enhance smoothness and clarity of the complexion [2].

Tretinoin’s Benefits

Wrinkle Reduction & Fine Line Improvement

Tretinoin has been studied for its role in improving the appearance of fine lines and wrinkles. In clinical research, 0.05% formulations used over several months demonstrated measurable changes in photoaged skin [3,4].

Youthful-Looking Skin & Elasticity

Through long-term use, tretinoin supports improved firmness and tone. These effects develop gradually as collagen synthesis and cell renewal continue [1].

Hyperpigmentation & Uneven Tone

Tretinoin may help reduce the visibility of dark spots and uneven tone over time by encouraging cell turnover [1]. It is sometimes prescribed for pigmentation disorders such as melasma under clinical guidance.

Texture & Smoothness

Users often report a smoother feel as rough or uneven areas improve with ongoing treatment [3].

Pore Appearance

By keeping pores clear, tretinoin can help reduce the visible prominence of pores, promoting a more refined appearance [2].

Before & After: What To Expect

Wrinkles & Fine Lines

In studies, regular tretinoin application improved the appearance of photoaged skin over 6 to 12 months [3]. The skin may appear smoother and more even in tone.

Hyperpigmentation & Dark Spots

Gradual fading of sun-induced pigmentation or post-acne marks can occur with consistent use, though results vary by individual [1].

Pores & Texture

Many users notice refinement of texture and pore visibility after months of continuous use [2].

Consistency & Patience

Visible improvements take time. In the first 2–6 weeks, temporary purging or dryness may occur [2]. Regular, correct use over several months typically provides the most noticeable outcomes.

How To Use Tretinoin For Best Results

Start Slow

Introduce tretinoin gradually (once or twice a week), especially for new users. Starting at a lower concentration such as 0.025% helps minimise dryness and irritation [2].

Apply To Clean & Dry Skin

Apply a pea-sized amount to clean, fully dry skin, avoiding sensitive areas like eyes and lips. Allow skin to dry for at least 20 minutes after cleansing [2].

Use A Pea-Size Amount

A small amount (roughly 0.25 g) is sufficient for the face. Applying more will not increase results and may increase irritation [2].

Moisturise & Protect

Always follow tretinoin with a gentle moisturiser. Daily sunscreen (SPF 30 or higher) is essential to prevent sun sensitivity and maintain skin health [2].

Potential Side Effects

Temporary redness, peeling, and dryness are common early reactions. These effects typically settle within several weeks [2]. Persistent discomfort should be reviewed by a prescribing clinician.

Managing Initial Irritation

Hydrating cleansers and moisturisers can help relieve dryness. Avoid combining tretinoin with other potentially irritating actives such as benzoyl peroxide or strong exfoliants unless directed by a clinician [2].

Long-Term Use & Tolerance

With continued use, most users find that their skin adjusts to tretinoin, allowing smoother and more even texture to emerge [3]. Maintaining consistency supports sustained benefits.

When To Seek Professional Advice

If irritation, dryness, or breakouts persist, consult a healthcare professional. They may recommend adjusting application frequency or strength. Clinical guidance ensures tretinoin is used safely and effectively.

Transformational Journeys

Long-term users often describe noticeable improvements in texture, clarity, and tone, contributing to overall skin confidence. Tretinoin has also shown promise in the management of early stretch marks under medical supervision [3].

Conclusion

Tretinoin can improve multiple visible signs of ageing and acne-related concerns when used consistently under professional direction. Results develop gradually, requiring patience, sun protection, and supportive skincare.

Those considering tretinoin should consult a healthcare professional for tailored advice. You can receive personalised guidance through a free online consultation reviewed by a GPhC-registered prescriber.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. Kang, S., et al. (1996). Topical tretinoin (retinoic acid) improves early stretch marks. Archives of Dermatology, 132(5), 519–526.
  2. Noble, S., & Wagstaff, A. J. (1995). Tretinoin: A review of its pharmacological properties and clinical efficacy in the topical treatment of photodamaged skin. Drugs & Aging, 6(6), 479–496.
  3. Schmidt, N., & Gans, E. H. (2011). Tretinoin: A review of its anti-inflammatory properties in the treatment of acne. Journal of Clinical and Aesthetic Dermatology, 4(11), 22–29.
  4. Weinstein, G. D., et al. (1991). Topical tretinoin for treatment of photodamaged skin: A multicenter study. Archives of Dermatology, 127(5), 659–665.
Categories
Treatments

Hyperpigmentation Tips For Uneven Skin Tone

Hyperpigmentation occurs when certain areas of the skin darken due to excess melanin production. It is common and generally harmless, though it can create uneven skin tone.

This article explains the causes, recognised treatments, and skincare steps for managing hyperpigmentation safely.

What Causes Hyperpigmentation

Several triggers can cause hyperpigmentation. Identifying these helps guide an appropriate care approach for different skin types.

Sun Exposure

Sunlight is one of the leading causes of hyperpigmentation. UV rays increase melanin production, forming sun spots on areas such as the face and hands.

Continuous exposure can worsen uneven tone, particularly in darker skin types [1]. Using a broad-spectrum sunscreen with SPF 30 or higher helps protect against this risk [9].

Hormonal Changes

Hormonal fluctuations, including pregnancy or hormonal therapy, can trigger melasma, often called the “mask of pregnancy.” Melasma affects between 8% and 50% of pregnant women, varying by skin tone and location [2].

Broader, symmetrical patches distinguish melasma from other forms. A healthcare professional can recommend suitable management options.

Skin Injuries & Inflammation

Post-inflammatory hyperpigmentation often follows acne, eczema, or minor skin injury. It is particularly common in darker skin tones [3]. Gentle skincare and early treatment support healing and help reduce lingering marks.

Medications

Certain medicines, such as minocycline, may darken the skin as a side effect. Minocycline-related pigmentation occurs in up to 15% of long-term users [4]. If this occurs, seek medical guidance before making changes to treatment.

Genetic Factors

Genetic traits influence the activity of melanocytes and overall pigmentation risk. People with darker complexions often have higher melanin activity [5]. Awareness of family patterns supports preventive skincare planning.

Effective Treatments For Hyperpigmentation

Several treatments can help reduce the appearance of dark spots. Suitability and outcomes depend on the underlying cause, consistency, and professional oversight.

Topical Treatments

Skin creams for hyperpigmentation often include ingredients such as hydroquinone, kojic acid, or vitamin C. Studies show 4% hydroquinone can improve dark patches within 12 weeks [6].

Kojic acid, a natural melanin inhibitor, can enhance skin brightness. Introduce active ingredients gradually to reduce irritation risk.

Hyperpigmentation & Tretinoin

Tretinoin increases cell turnover, helping to fade dark marks and smooth skin texture. It is effective in melasma and post-inflammatory hyperpigmentation when used under clinical supervision [12].

As a prescription-only medicine in the UK, tretinoin should be used as directed by a qualified prescriber and always alongside daily sunscreen.

Chemical Peel For Hyperpigmentation

Chemical peels gently exfoliate the skin and improve texture. Trichloroacetic acid (TCA) peels have shown clinical benefit for uneven pigmentation [7].

Post-treatment hydration supports recovery, and a healthcare professional should carry out the procedure.

Laser Therapy

Laser therapy targets excess melanin in the skin and can help with stubborn pigmentation cases [8]. It should be performed by trained clinicians, as suitability and outcomes vary.

Treatment TypeBenefitTimeframeConsideration
Topical CreamsLightens dark areas8–12 weeksMay cause irritation
TretinoinBoosts skin renewal12–24 weeksPrescription only
Chemical PeelsImproves evenness4–8 weeksProfessional procedure
Laser TherapyReduces persistent marks6–12 weeksHigher cost

Table 1: Common treatments and considerations

Preventing Hyperpigmentation

Preventive skincare habits protect the skin from new pigmentation and maintain a balanced tone.

Daily Sun Protection

Sunscreen for hyperpigmentation helps prevent dark spots and uneven tone. The NHS recommends broad-spectrum SPF 30, reapplied every two hours outdoors [9]. This step benefits all skin tones and is especially important for those with prior pigmentation issues [10].

Gentle Hyperpigmentation Skincare

A consistent routine using vitamin C, niacinamide, or kojic acid supports skin balance. Antioxidants in skincare and diet can help protect skin cells from oxidative stress [11]. Weekly exfoliation and adequate hydration contribute to smoother, healthier-looking skin.

Monderma’s Custom Formula For Hyperpigmentation

Monderma provides prescription-strength formulations created by UK-registered clinicians and dispensed by a GPhC-registered pharmacy. Each treatment is tailored to individual skin needs after a clinical review.

IngredientStrengthDescriptionHow It Supports Even Tone
Adapalene0.1–0.3%Vitamin A retinoidPromotes cell renewal & reduces new marks
Azelaic Acid3–20%Naturally derived acidHelps reduce melanin activity & refine tone
Hydroquinone2–4%Prescription-only agentReduces melanin formation under supervision
Niacinamide2–4%Vitamin B3 derivativeSupports brightness & decreases pigment transfer
Tretinoin0.01–0.1%Prescription retinoidIncreases turnover & improves uneven tone

Table 2: Key ingredients and their benefits for even skin tone

Conclusion

Hyperpigmentation can often be managed through consistent skincare, professional assessment, and daily sun protection. Evidence-based ingredients such as hydroquinone, azelaic acid, and tretinoin may help improve uneven tone when clinically appropriate.

You can complete a quick, free online consultation reviewed by a GPhC-registered prescriber to see if a prescription-strength formula could be right for your skin.

Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.

Bibliography

  1. Del Bino, S. et al. “Variations in skin colour and the biological consequences of ultraviolet radiation exposure.” British Journal of Dermatology, 2013, 169(s3):33-40.
  2. Ogbechie-Godec, O.A. “Melasma: an Up-to-Date Comprehensive Review.” Dermatology Research and Practice, 2017.
  3. Davis E.C., Callender V.D. “Postinflammatory hyperpigmentation: a review of the epidemiology, clinical features, and treatment options in skin of colour.” Journal of Clinical and Aesthetic Dermatology, 2010; 3(7):20-31.
  4. Eisen D., Hakim M.D. “Minocycline-induced pigmentation. Incidence, prevention and management.” Drug Safety, 1998; 18(6):431-440.
  5. Bajpai, V.K., et al. “A genome-wide genetic screen uncovers novel regulators of melanogenesis.” bioRxiv, 2021.
  6. Monteiro, R.C., et al. “A Comparative Study of the Efficacy of 4% Hydroquinone vs 0.75% Kojic Acid Cream in the Treatment of Melasma.” Journal of Clinical and Aesthetic Dermatology, 2012.
  7. Sitohang, I.B.S., et al. “Trichloroacetic Acid Peeling for Treating Photoaging: A Systematic Review.” Journal of Cutaneous and Aesthetic Surgery, 2021.
  8. Sarkar R., Gokhale N., Godse K., et al. “Lasers in Melasma: A Review with Consensus Recommendations by the Pigmentary Disorders Society (PDS), India.” Journal of Clinical and Aesthetic Dermatology, 2017; 10(1):34-45.
  9. NHS. “Sunscreen and Sun Safety,” 2025.
  10. Fatima, S., et al. “The Role of Sunscreen in Melasma and Postinflammatory Hyperpigmentation.” Journal of Clinical and Aesthetic Dermatology, 2020.
  11. Addor, F.A.S. “Antioxidants in Dermatology.” Journal of the European Academy of Dermatology and Venereology, 2013, 27(Suppl 1):19-23.
  12. Moolla S., Miller-Monthrope Y. “Dermatology: How to Manage Facial Hyperpigmentation in Skin of Colour.” Canadian Family Physician, 2022; 68(5):357-359.