Monderma- 28 Feb 2025
- Plant compound that calms skin
- Helps reduce visible redness
- Evidence mostly from lab studies
- Generally gentle for most users
- Supports Monderma’s active ingredients
Bisabolol is a plant derived ingredient that supports calm and comfort in sensitive or irritated skin [1,5]. Many adults notice dryness or redness at times, making gentle ingredients feel especially relevant.
This article explains how bisabolol works, where its evidence comes from, and why it is often included in products designed for skin prone to discomfort or inflammation [1,2,5].
What Is Bisabolol?
Bisabolol is a natural sesquiterpene alcohol found in German chamomile and in the bark of the candeia tree [1,4,5]. It is valued for its soothing properties and its ability to support comfortable feeling skin.
Chemical Composition
Bisabolol is a monocyclic sesquiterpene alcohol that absorbs into the outer layers of the skin [1,5]. Researchers are studying how well it enhances the activity of other skincare ingredients.
Anti Inflammatory Effects
Bisabolol reduces inflammatory signals in preclinical models and cell studies [1,2]. These findings suggest possible benefits for skin prone to redness, sensitivity, or environmental irritation.
Mechanism Of Action
Bisabolol helps reduce irritation by limiting chemical messages that drive inflammation [1,2]. It influences internal pathways in skin cells, which lowers the production of proteins linked with redness and swelling.
Cosmetic Benefits
Bisabolol is included in skincare for its softening and soothing qualities [1,2]. Laboratory work shows mild antimicrobial activity, yet its main value lies in calming and hydrating skin rather than treating infections.
Safety & Tolerability
Bisabolol is generally well tolerated with low sensitisation rates [3]. Patch testing is sensible for those with sensitive skin or a history of allergy. Rare reactions mainly occur in people with atopic backgrounds [3].
Summary Table
| Feature | Description |
|---|---|
| Main actions | Soothing and calming effects [1,2] |
| Evidence base | Mostly laboratory research [1,2,5] |
| Tolerability | Low irritation risk [3] |
| Common use | Sensitive or dry skin products [1,5] |
Table 1: Key bisabolol features
Monderma Support For Skin Concerns
Monderma offers personalised prescription skincare for concerns such as acne, ageing skin, hyperpigmentation, and rosacea. Treatments are prepared after clinical review and adjusted to individual needs.
Conclusion
Most evidence for bisabolol comes from laboratory research, yet its soothing and hydrating qualities make it a useful ingredient for sensitive skin. In practice, many people use bisabolol for comfort, calm, and general support rather than for specific medical conditions.
Those seeking tailored help for ongoing skin needs can explore care through our expert skincare consultation, which connects individuals with pharmacist led guidance.
Content is for informational purposes only. Monderma treatments are prescribed following consultation. Results and timeframes can vary. Use as directed by your prescriber.
References
- Lujain Bader Eddin, Jha NK, Goyal SN, Agrawal YO, Subramanya SB, Bastaki SMA, Ojha S. Health Benefits, Pharmacological Effects, Molecular Mechanisms, and Therapeutic Potential of Alpha Bisabolol. Nutrients. 2022.
- Maurya AK, Singh M, Dubey V, Srivastava S, Luqman S, Bawankule DU. Alpha Bisabolol Reduces Pro Inflammatory Cytokine Production and Ameliorates Skin Inflammation. Current Pharmaceutical Biotechnology. 2014.
- Fiume MM. Safety Assessment of Bisabolol as Used in Cosmetics. Cosmetic Ingredient Review Expert Panel. 2015.
- Sah A, Naseef PP, Kuruniyan MS, Jain GK, Zakir F, Aggarwal G. A Comprehensive Study of Therapeutic Applications of Chamomile. Pharmaceuticals. 2022.
- Albertti LAG, Delatte TL, de Farias KS, Boaretto AG, Verstappen F, van Houwelingen A, Cankar K, Carollo CA, Bouwmeester HJ, Beekwilder J. Identification of the Bisabolol Synthase in the Candeia Tree. Frontiers in Plant Science. 2018.
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