Tretinoin For Skin Renewal
Tretinoin is a vitamin A–derived retinoid, clinically shown to increase skin cell turnover. It is widely used to help improve the appearance of pores, support clearer skin, and reduce the look of fine lines.
First developed in the 1950s and approved for UK use in 1983, tretinoin remains one of dermatology’s most established prescription options for skin renewal.
How Does It Work?
Get your tretinoin formula in 3 simple steps with Monderma:
Complete
a quick, free skin consultation
Start
your personalised monthly formula
Adjust
with progress—cancel, restart anytime
What's In Your Tretinoin Formula?
Shipped in a vegan base with hydrating hyaluronic acid and peptides, your blend may also include up to 2 other active ingredients, namely azelaic acid, clindamycin, hydroquinone, ivermectin, or niacinamide.
GPhC Registered Pharmacy
MHRA Approved Suppliers
Dermatologically Tested
Money Back Guarantee
Recyclable
Vegan Friendly
Cruelty Free
Fragrance Free
Alcohol Free
Paraben Free
Sulfate Free
Gluten Free
Micronised
Highly Spreadable
Non Comedogenic
The Monderma Difference
 |
VS | Retail |
|---|---|---|
| Retinoid | Retinol | |
| 3-In-1 | 3 Creams | |
| Personalised Formula | Batch Produced | |
| Up To 20x Strength | Limited Efficacy | |
| Pharmacist Led | Retail | |
| Dermatological | Cosmetic | |
Tretinoin For Skin Renewal
Monderma tretinoin formulas are prescribed and dispensed by GPhC-registered prescribers and pharmacists, ensuring safe and clinically guided use.
While results vary, many patients notice smoother-looking skin with fewer visible fine lines, more even texture, and clearer pores after consistent use. Some may experience temporary peeling, dryness, or redness as the skin adjusts.
Tried, Tested, Loved: Hear It Firsthand
My skin is looking great and is very happy!
Packaging is very luxurious and the cream itself is a lovely consistency which absorbs in to the skin.
– Loli, Cornwall, UK
Skin feels clearer already!
Really good product to use and excellent results within a few weeks so far.
– Sadie, Surrey, UK
Amazing custom skin formulae high quality and value
It’s been about 3 months since I’ve been using Monderma, and I can say I’ve seen transformative results on my face.
– Emma, Lincoln, UK
Help refine pores, improve the look of breakouts, and smooth the appearance of fine lines with a tretinoin formula.
Shop now to save 50% and enjoy free shipping with Monderma – limited time only.
Still Have Questions?
Monderma's tretinoin is typically applied to your face. It can also be used on your neck and under-eye area with moisturiser. A low strength is recommended for these areas, as they are more sensitive. Avoid applying it too close to your eyelids.
Apply TWO pumps to clean, dry skin on the affected area(s) once daily at NIGHT. After application, wash your hands and follow up with applying a moisturiser. Use a sunscreen of SPF30 or higher daily to protect your skin.
Monderma prescribes tretinoin in strengths ranging from 0.01% to a maximum of 0.1%, in accordance with national guidelines.
The most suitable strength for you varies based on several factors, including whether it is acne, ageing skin, or hyperpigmentation being treated, prior use of retinoids, and individual skin response. Starting too high or increasing strength too quickly can lead to skin irritation.
While some users gradually increase their strength, the majority find that maintaining a consistent, lower concentration provides optimal results for their skin.
You may start to see visible results after 1 week. However, for lasting results, we recommend nightly use for at least 12 weeks.
In most cases, tretinoin is a safe and reliable ingredient for long-term use.
Although tretinoin is designed to treat skin conditions, some users may experience mild side effects. This includes peeling, tingling, and redness, particularly during the initial adjustment period.
To minimise this risk, Monderma recommends starting with a lower strength and applying a moisturiser to support your skin as it adapts.
Tretinoin is not safe for use during pregnancy. If you are trying to conceive, become pregnant, or are breastfeeding, discontinue use immediately and contact us for further guidance.
Tretinoin should not be used with harsh exfoliants, alcohol-based products, retinol, benzoyl peroxide, or salicylic acid at the same time, as these can cause skin irritation. However, it is generally safe to combine with most other over-the-counter skincare products.
If you need to use any other prescription skincare, you must notify Monderma to ensure your tretinoin formula is safe for continued use.
Additionally, always notify each healthcare or procedure provider about your prescription skincare use. Some procedures may require pausing application before and after to minimise the risk of skin sensitivity and adverse reactions.