Leaflet

Before using Monderma’s personalised skincare, please read this information carefully.

Monderma’s personalised skincare contains a combination of active pharmaceutical ingredients, excipients, and a base cream. It is prescribed to treat facial acne, wrinkles, hyperpigmentation, or rosacea. This medicine is available only after completing an online consultation with a GMC or GPhC registered prescriber and is suitable for adults aged 16 and over.

Each prescription is supplied as a 15g off-white cream in an airtight pump container.

Active Pharmaceutical Ingredients

Each prescription contains up to three of the following active pharmaceutical ingredients, selected to target specific skin concerns:

Adapalene: a retinoid and vitamin A derivative that helps regulate cell turnover on the surface of the skin to improve texture and tone.

Azelaic acid: an anti-inflammatory that limits the production of inflammatory-causing molecules to reduce redness and irritation.

Clindamycin: an antibiotic that fights bacteria on the skin to decrease bumps and swelling.

Ectoine: an antioxidant that increases moisture retention to improve hydration and reduce sensitivity.

Hydroquinone: a skin lightening agent that limits the production of melanin to reduce the appearance of areas of darker skin.

Ivermectin: an antiparasitic agent that decreases the number of Demodex mites to reduce redness and swelling.

Niacinamide: an antioxidant and vitamin B3 that helps protect against free radicals by repairing and strengthening the barrier function of the skin to lock in moisture.

Tranexamic acid: a lysine derivative that inhibits melanocyte activation to reduce the appearance of areas of darker skin.

Tretinoin: a retinoid and vitamin A derivative that regulates the growth of cells on the surface of the skin to improve its texture and tone.

The pump container and box include a dispensing label listing the active pharmaceutical ingredients, strengths, directions for use, and key safety information.

Excipients

Monderma uses the following excipients in some formulas to support stability, absorption, and preservation:

Butylated hydroxytoluene: an antioxidant and preservative that prevents the growth of bacteria, yeast, and mould to support stability.

Citric acid: an antioxidant and preservative used to help regulate pH and maintain the skin’s barrier function.

Sodium metabisulfite: an antioxidant and preservative used to reduce oxidation and minimise discolouration.

Each prescription with tretinoin includes butylated hydroxytoluene. Each prescription containing hydroquinone includes citric acid and sodium metabisulfite.

Base Cream

Monderma uses a base cream designed to provide moisture, enhance absorption, reduce inflammation, and help regulate sebum production. Each formula contains the following ingredients:

Water, 1,3-propanediol, edetate disodium dihydrate, hyaluronic acid, candelilla/jojoba/rice bran polyglyceryl-3 esters, glyceryl stearate, cetearyl alcohol, sodium stearoyl lactylate, cetearyl alcohol, undecane, tridecane, simethicone, hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, c13-14 isoalkane, polysorbate 80, decyl glucoside, glycerin, phenoxyethanol, ethylhexylglycerin, hydroxycinnamic acid, bisabolol, butylene glycol, dextran, palmitoyl tripeptide-8, persea gratissima oil, simmondsia chinensis seed oil, rosa canina flower oil, tocopheryl acetate, cocos nucifera oil, lavandula angustifolia herb oil, melaleuca alternifolia leaf oil, rosemarinus officinalis leaf oil, butyrospermum parkii butter, and caprylic/capric triglyceride.

Each prescription is highly spreadable, and suitable for all skin tones and types. It is free of dyes, parabens, mineral oils, sodium lauryl sulfate, propylene glycol, and petroleum.

Apply TWO pumps to clean, dry skin on the affected area(s) once daily at NIGHT.

Wash your hands thoroughly after application and follow with a moisturiser.

Consistent use is important for optimal results. Allow up to 12 weeks for visible improvement.

Take the following precautions when using your prescription:

  • Do not use if you are allergic to any ingredients in your prescription.
  • For external use only; do not swallow.
  • Avoid the eyes and other sensitive areas, and irritated, broken, or sunburned skin.
  • Do not apply to skin tags, moles, warts, or any raised or undiagnosed lesions.
  • Avoid use before or after shaving, and ask your practitioner when to pause before and after hair removal, laser, or injectables.
  • Avoid use immediately before or after shaving or hair removal, and ask your practitioner how long to pause before and after laser or injectable treatments.
  • Avoid using other topical or oral retinoids at the same time.
  • Apply sunscreen daily with a minimum SPF of 30, even on cloudy days, and do not use sunbeds.
  • Stop using immediately if you are trying to conceive, become pregnant, or are breastfeeding.
  • Do not share your prescription with anyone else.

Monderma’s prescriptions are not known to affect your ability to drive or use machinery.

Always ensure the safe and responsible handling of your prescription:

  • Keep your prescription in its original container.
  • Store in a cool, dry place away from direct sunlight; do not store above 25°C and do not refrigerate or freeze.
  • Keep out of the reach and sight of children and animals.
  • Do not use your prescription after the expiry date on its dispensing label.
  • Do not flush unused prescription down the toilet, pour it down the sink, or dispose of it in general waste.
  • Return any unused prescription to a local pharmacy for safe disposal.

When not in use, replace the cap securely to reduce exposure to air and prevent oxidation.

Although your prescription is formulated to treat skin conditions, it may cause side effects, although not everyone will experience them.

It is common to notice mild dryness, peeling, redness, or tingling when first starting retinoids. This is part of the retinisation process and shows that your active ingredients are beginning to work. These symptoms may continue for several weeks. If they persist or become uncomfortable, reduce application to ONE to TWO pumps every other night until symptoms improve.

If you start any new medication or if your medical circumstances change, contact us immediately.

If you experience severe dryness, peeling, redness, or burning, stop using your prescription immediately. Speak to a GP, pharmacist, or nurse, and contact us for further guidance.

If you notice any raised or irregular-shaped lesions or moles, seek advice from a GP, pharmacist, or nurse without delay. Monderma does not diagnose or treat skin cancers.

You can report side effects to the MHRA by completing a Yellow Card at any pharmacy or online.

Your prescription is prepared under section 10 of the Medicines Act 1968 and is supplied as an unlicensed special medicinal product. This means it does not require marketing authorisation or registration.